<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation K43R
Rx >= 1 PI
IncludeMixtures No
References 4
Patients 5
Isolates 5
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Seyler (2007)265CS_265 IDV66  L10V, I13V, L19P, K20I, M36I, R41K, K43R, L63LP, H69K, L89MA
Kouri (2012)CU1908-09CU1908-09JQ585320PINAM46I, I54V, V82F, L90ML33F, T74PK20I, E35N, M36I, R41K, K43R, F53Y, R57K, I62V, L63P, H69K, I85V, R87RK, L89MA
Grossman (2014)421421 IDV, LPV52  L10M, I13V, K20KR, E35D, M36I, R41K, K43R, R57K, L63LIPT, H69K, L89MA
Diaz (2015)RenG15076RenG15076KT746104PINAM46I, V82FF53L, N83DW6V, L10V, I13A, A22V, E35D, M36I, R41K, K43R, R57K, Q61N, I62V, L63P, H69R, T74S, L89I, I93LA
 RenG11119RenG11119KT742147PINAI50LL33LF, F53LG17E, K20R, E35D, M36I, N37DE, R41K, K43R, K45N, R57K, D60N, Q61N, L63T, I72T, V82VI, L89MA