Protease Inhibitors

HOME Genotype-Rx Genotype-Pheno Genotype-Clinical hivdb program

Protease Inhibitors

Subtype	A
Gene	PR
Mutation	M36L
Rx	PI-naive
IncludeMixtures	No

References	21
Patients	25
Isolates	26

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	PIs	OtherMut	Subtype
Nkengasong (2000)	JN_IC28	JN_IC28	AF216987	None	I13V, L19I, K20I, M36L, L38F, R41K, L63P, H69K, L89M	A
Eshleman (2004)	ESH_Pat22	ESH45	AY435228	None	I13V, K14R, E35D, M36L, R41K, R57K, L63P, H69K, L89M	A
Eshleman (2004)		SE45_7d	AY428672	None	I13V, K14R, E35D, M36L, R41K, R57K, L63P, H69K, L89M	A
Kijak (2004)	1152NG	01CM.1152	AY371163	None	L10V, I13V, E35D, M36L, R41K, H69K, L89M	A
Vazquez de Parga (2005)	IR63B	IR63B	EU345674	None	I13V, K14R, E35D, M36L, R41K, H69K, V77I, L89M, I93L	A
Koizumi (2006)	YK_04CM072	YK_04CM072	DQ461860	None	I13V, E35N, M36L, N37D, R41K, H69K, L89M	A
Marechal (2006)	JF_007	JF_007	DQ443629	None	L10V, I13V, E35D, M36L, R41K, R57K, L63T, H69K, L89M	A
	JF_016	JF_016	DQ443637	None	L10IV, T12TS, I13V, K14KN, G16E, L19LI, M36L, N37NHRS, R41K, L63T, I72V, L89M	A
Vessiere (2006)	AV_M4606N	AV_M4606N	DQ297201	None	I13V, G16E, G17DE, K20KR, E35D, M36L, R41K, L63A, H69K, K70R, L89M, T91V, I93L	A
Church (2007)	045-109688N	045	EF612002	None	I13V, K14R, E35D, M36L, R41K, R57K, L63P, H69K, L89M	A
von Wyl (2007)	70	492471	EF450026	None	I13V, M36L, N37S, R41K, I64IV, H69K, L89I	A
Aghokeng (2009)	HG_0943	HG_0943	GU191658	None	I13V, I15V, L19I, E35D, M36L, R41K, R57RK, I62IV, H69K, V77I, L89M	A
Vercauteren (2009)	pt864	7odC6dxTFE	GQ400160	None	L10V, I13V, E35D, M36L, R41K, L63P, H69K, I72M, L89M	A
Djoko (2010)	683	CD4078	FR666683	None	L10I, I13V, G17E, E35D, M36L, R57RK, L63T, C67F, H69K, I72IV, L89M	A
Tovanabutra (2010)	KECst_017	KECst_017	FJ623488	None	L10V, I13V, I15V, L19V, E35D, M36L, N37D, R41K, R57K, D60E, Q61E, L63V, E65D, H69K, L89M	A
Aghokeng (2011)	SK8034-PI	SK8034-PI	HQ864342	None	L10IV, I13V, K20KT, E35DN, M36L, N37D, R41K, R57K, L63P, H69K, L89M	A
	SK8040-PI	SK8040-PI	HQ864343	None	I13IV, I15V, E35D, M36L, R41K, I62IV, L63T, I64M, H69K, L89M	A
Charpentier (2011)	6	CP 001 071		None	P1PS, L10LIV, T12TAIV, I13IV, I15IV, G16GE, M36L, R41K, L63T, H69K, I72IT, L89M	A
	179	CP 001 1982		None	G16A, E35D, M36L, R41K, I62V, H69K, T74S, L89M	A
Hamers (2011)	CP076301722	CP076301722	HQ993715	None	T12TP, I13V, G16E, E35D, M36L, R41K, R57K, L63T, I64L, H69K, L89M	A
	CP076302000	CP076302000	HQ995182	None	K14R, G16E, M36L, R41K, H69K, L89M	A
	CP076303109	CP076303109	HQ995285	None	I13V, E35D, M36L, P39Q, R41K, R57K, L63P, I64L, H69K, L89M	A
Ndembi (2011)	NTCPS724	NTCPS724	HQ702622	None	I13V, K14R, E35D, M36L, R41K, K45R, R57K, L63T, H69K, V77I, L89M	A
De Gascun (2012)	IRL15546	IRL15546	JN622345	None	L10V, I13V, K14R, I15V, G16E, L19L*Q, M36L, R41K, L63T, C67CR, H69K, L89M	A
Ssemwanga (2012)	RCC_TDR-482974	RCC_TDR-482974	JQ266085	None	L10I, I13V, M36L, R41K, H69Q, L89I	A
Frentz (2013)	EHR-65414	EHR-65414	JX300641	None	L10V, I13V, K14R, G16E, M36L, N37S, R41K, L63T, H69K, L89M	A

Protease Inhibitors

Database

Resources

Team