<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation M36L
Rx PI-naive
IncludeMixtures No
References 29
Patients 34
Isolates 35
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Nkengasong (2000)JN_IC28JN_IC28AF216987None   I13V, L19I, K20I, M36L, L38F, R41K, L63P, H69K, L89MA
Eshleman (2004)ESH_Pat22ESH45AY435228None   I13V, K14R, E35D, M36L, R41K, R57K, L63P, H69K, L89MA
Eshleman (2004) SE45_7dAY428672None   I13V, K14R, E35D, M36L, R41K, R57K, L63P, H69K, L89MA
Kijak (2004)1152NG01CM.1152AY371163None   L10V, I13V, E35D, M36L, R41K, H69K, L89MA
Vazquez de Parga (2005)IR63BIR63BEU345674None   I13V, K14R, E35D, M36L, R41K, H69K, V77I, L89M, I93LA
Koizumi (2006)YK_04CM072YK_04CM072DQ461860None   I13V, E35N, M36L, N37D, R41K, H69K, L89MA
Marechal (2006)JF_007JF_007DQ443629None   L10V, I13V, E35D, M36L, R41K, R57K, L63T, H69K, L89MA
 JF_016JF_016DQ443637None   L10IV, T12TS, I13V, K14KN, G16E, L19LI, M36L, N37NHRS, R41K, L63T, I72V, L89MA
Niama (2006)ARV64ARV64FM164892None   L10V, T12V, I13V, M36L, N37D, I62V, L63P, H69K, L89MA
Vessiere (2006)AV_M4606NAV_M4606NDQ297201None   I13V, G16E, G17DE, K20KR, E35D, M36L, R41K, L63A, H69K, K70R, L89M, T91V, I93LA
Church (2007)045-109688N045EF612002None   I13V, K14R, E35D, M36L, R41K, R57K, L63P, H69K, L89MA
von Wyl (2007)70492471EF450026None   I13V, M36L, N37S, R41K, I64IV, H69K, L89IA
Aghokeng (2009)HG_0943HG_0943GU191658None   I13V, I15V, L19I, E35D, M36L, R41K, R57RK, I62IV, H69K, V77I, L89MA
Vercauteren (2009)pt8647odC6dxTFEGQ400160None   L10V, I13V, E35D, M36L, R41K, L63P, H69K, I72M, L89MA
Djoko (2010)683CD4078FR666683None   L10I, I13V, G17E, E35D, M36L, R57RK, L63T, C67F, H69K, I72IV, L89MA
Tovanabutra (2010)KECst_017KECst_017FJ623488None   L10V, I13V, I15V, L19V, E35D, M36L, N37D, R41K, R57K, D60E, Q61E, L63V, E65D, H69K, L89MA
Aghokeng (2011)SK8034-PISK8034-PIHQ864342None   L10IV, I13V, K20KT, E35DN, M36L, N37D, R41K, R57K, L63P, H69K, L89MA
 SK8040-PISK8040-PIHQ864343None   I13IV, I15V, E35D, M36L, R41K, I62IV, L63T, I64M, H69K, L89MA
Charpentier (2011)6CP001071 None   P1PS, L10LIV, T12TAIV, I13IV, I15IV, G16GE, M36L, R41K, L63T, H69K, I72IT, L89MA
 179CP0011982 None   G16A, E35D, M36L, R41K, I62V, H69K, T74S, L89MA
Hamers (2011)CP076301722CP076301722HQ993715None   T12TP, I13V, G16E, E35D, M36L, R41K, R57K, L63T, I64L, H69K, L89MA
 CP076302000CP076302000HQ995182None   K14R, G16E, M36L, R41K, H69K, L89MA
 CP076303109CP076303109HQ995285None   I13V, E35D, M36L, P39Q, R41K, R57K, L63P, I64L, H69K, L89MA
Ndembi (2011)NTCPS724NTCPS724HQ702622None   I13V, K14R, E35D, M36L, R41K, K45R, R57K, L63T, H69K, V77I, L89MA
De Gascun (2012)IRL15546IRL15546JN622345None   L10V, I13V, K14R, I15V, G16E, L19L*Q, M36L, R41K, L63T, C67CR, H69K, L89MA
Ndase (2012)5800916258009162KC900719None   I13V, G16E, E35D, M36L, P39S, R41K, R57K, L63T, H69K, V77I, L89MA
 5600924256009242KC900755None   I13V, K14KR, E35D, M36L, N37D, R41K, R57K, D60E, H69K, L89MA
Ssemwanga (2012)RCC_TDR-482974RCC_TDR-482974JQ266085None   L10I, I13V, M36L, R41K, H69Q, L89IA
Frentz (2013)EHR-65414EHR-65414JX300641None   L10V, I13V, K14R, G16E, M36L, N37S, R41K, L63T, H69K, L89MA
Hassan (2014)RS11000460RS11_460KC568520None   E35D, M36L, N37E, R41K, R57K, L63LV, H69K, L89MA
Bruzzone (2015)MB0197FMB0197FEU914180None   L10V, I13V, I15V, E35D, M36L, R41K, L63T, H69R, L89MA
Laga (2015)AM033AM033KF720959None   I13V, K14R, G16A, E35D_IN, M36L, R41K, L63P, H69K, V77I, L89M, I93LA
Boillot (2016)MAT03MAT03KT315971None   I13V, M36L, R41K, L63LFPS, H69K, L89M, Q92QPA
Gashnikova (2016)Tyumen69Tyumen69KX640176None   I13V, E35D, M36L, R41K, H69K, L89M, I93LA
Zeh (2016)0012440_040012440_04KU248525None   M36L, R41K, R57RK, L63LP, E65EK, G68GE, H69K, L89MA