<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation E35N
Rx >= 1 PI
IncludeMixtures No
References 10
Patients 12
Isolates 12
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Chantratita (2005)NP304NP304DQ130384PINAG48V, I54T, V82A L10V, T12P, I13V, G16A, K20I, E35N, M36I, R41K, R57K, L63P, H69K, T74S, L89MA
Non-B Workgroup (2005)TK4006TK4006 NFV83N88SL10FI13V, I15V, K20I, E35N, M36I, R41K, K45R, R57Q, H69K, L89IA
Baxter (2006)48-50215021-30606DQ878555PINAI54V, V82F, I84IV, L90ML33F, F53LL10I, V11L, I13V, I15V, G16E, L19P, K20I, E35N, M36I, K45V, L63T, H69K, L89MA
Kouri (2012)CU544-09CU544-09JQ585255PINAM46I, I47V, I54V, I84V, L90ML10F, V11VI, L33I, Q58E, G73S, T74P, N88G, L89VI13AV, K14R, K20IT, E35N, M36I, N37D, R41K, I62V, L63V, H69K, K70RA
 CU1908-09CU1908-09JQ585320PINAM46I, I54V, V82F, L90ML33F, T74PK20I, E35N, M36I, R41K, K43R, F53Y, R57K, I62V, L63P, H69K, I85V, R87RK, L89MA
Mollan (2012)MK186MK186w26 RTV, ATV25  I13V, E35N, M36I, R41K, R57K, H69K, L89MA
Reynolds (2012)J7227J0722-2JN652210LPV   I13V, K20I, A22AV, E35N, M36I, R41K, H69K, V77I, L89MA
Agyingi (2014)LB086LB086KF576441PINA  E21X, E35N, M36I, N37D, R41K, L63P, C67Y, H69K, V77I, L89MA
Jenabian (2015)DR06DR06KF735817PINA  L10V, I13V, K14R, G16E, L19V, K20KR, E35N, M36I, N37D, R41K, Q61G, L63T, E65D, H69K, L89MA
 DR05DR05KF735816PINA  I13V, K20R, E35N, M36I, N37D, R41K, K43R, R57K, L63P, H69K, K70R, L89MA
Sutherland (2015)44_POSTKT351836LPV M46MI, V82VA L10I, I13V, K14KR, K20I, E35N, M36I, R41K, R57K, H69K, V77I, L89MA
Ndahimana Jd Riedel (2016)21412141KT982484LPV M46I, I54V, L76V, I84V L10I, I13A, K14R, I15V, K20I, E35N, M36I, R41K, K45R, K55R, R57K, I66F, H69K, L89I, I93VA