<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L33F
Rx PI-naive
IncludeMixtures No
References 29
Patients 40
Isolates 40
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Cornelissen (1997)92RW00892RW008AF009407None  L33FI13V, K14R, E35D, R41K, K45R, R57K, H69K, L89MA
Becker-Pergola (2000)171.005BPG171-005AF177351None  L33FI13V, E35D, M36I, R41K, K45R, R57K, G68E, H69K, L89MA
Eshleman (2001)SE660SE660AF388111None  L33FI13V, E35D, M36I, R41K, R57K, H69K, L89MA
 SE655SE655AF388110None  L33FI13V, K14R, E35D, M36I, R41K, R57K, H69K, L89MA
Koch (2001)NK-18NK-18AY007747None  L33FL10I, I13V, K14R, K20R, M36I, R41K, R57K, L63V, H69Q, K70R, L89MA
Servais (2004)SJ_Pat33SJKLM042AJ412962None  L33FI13V, K14R, I15V, G16E, K20I, E35D, M36I, R41K, R57K, H69K, L89MA
Yang (2004)99KE59199KE591AY492781None  L33FI13V, E35D, M36I, N37D, R41K, R57K, E65D, H69K, L89MA
Brown (2005)BB_92UG_02992UG_029AY713407None  L33FI13V, E35D, M36I, R41K, K45R, R57K, Y59H, H69K, L89MA
Tee (2005)04MYKLCCK04_CCKAY904600None  L33FM36I, R57K, H69K, L89MA
Razafindratsimandresy (2006)RR_MAD-TI058MAD-TI058DQ345017None  L33FI13V, K14R, K20I, E35D, M36I, R41K, K45R, R57K, L63P, C67Y, H69K, K70R, L89MA
Church (2007)133750R133750REF612185None  L33FI13V, E35D, M36I, R41K, R57K, H69K, L89MA
Galluzzo (2007)23340RW_23340JQ220047None  L33FI13V, K14R, Q18QH, E35D, M36I, R41K, R57K, H69K, K70KR, V77VI, L89MA
Razafindratsimandresy (2007)1414HIV-SEYEF143506None  L33FI13V, G16GE, K20R, M36I, R41K, R57K, H69K, K70R, L89MA
von Wyl (2007)15766307EF449883None  L33FI13V, K14R, I15V, G16E, E35D, M36I, R41K, K45R, R57K, H69K, L89MA
Eshleman (2009)H28745W207-156961FJ389079None  L33FT4TN, I13V, M36I, R41K, R57K, E65D, H69K, L89MA
Balode (2010)S2303S2303GU945173None  L33FI13V, K14R, E35D, M36I, P39PL, R41K, L63T, C67E, H69K, V77I, L89M, I93LA
Hattori (2010)C05-2066263C05-2066263AB864008None  L33FI13V, E35D, M36I, R41K, R57K, E65D, H69K, R87K, L89MA
Mosha (2010)S5polS5polJQ071453None  L33FI13V, K14R, M36I, R41K, K45R, R57K, H69Q, L89MA
Hamers (2011)CP076301540CP076301540HQ993583None  L33FI13V, K14R, M36I, R41K, R57K, E65ED, H69K, L89MA
 CP076302282CP076302282HQ993832None  L33FI13V, K14R, E35D, M36I, P39PS, R41K, R57K, H69K, L89MA
 CP076302304CP076302304HQ993850None  L33FL10V, I13V, K14R, E35D, M36I, N37D, R41K, K45R, R57K, Q61E, L63LAPV, C67Y, H69K, V77VI, L89MA
 CP076303070CP076303070HQ995250None  L33FI13V, E35D, M36I, R41K, R57K, H69K, L89MA
 CP076303104CP076303104HQ995280None  L33FI13V, M36I, R41K, R57K, I62V, L63S, H69K, L89MA
 CP076301996CP076301996HQ995450None  L33FI13V, M36I, R41K, E65D, H69K, V77I, L89MA
 CP076302011CP076302011HQ995453None  L33FI13V, K20R, E35D, M36I, R41K, R57K, H69K, L89MA
Ndembi (2011)AICPS283AICPS283HQ702652None  L33FI13V, E35D, M36I, R41K, I62V, L63P, I64L, H69K, K70R, L89MA
 AICPS001AICPS001HQ702677None  L33FI13V, K14R, G17D, E35D, M36T, R41K, R57K, L63V, E65D, H69K, V77I, L89MA
Afonso (2012)ANG44ANG44JN937057None  L33FE35D, M36I, R41K, L63H, H69K, K70R, I72V, V77I, L89MA
Nazziwa (2012)10116011011601JX498971None  L33FI13V, M36I, R41K, R57K, H69K, L89MA
Sigaloff (2012)KELKN266KELKN266JN628524None  L33FI13V, K14R, E35D, M36I, R41K, R57K, L63V, H69K, L89M, L97IA
Yang (2012)KN-12KN-12JQ616914None  L33FT12S, I13V, K14R, E35D, M36I, N37D, R41K, R57K, I62IV, E65D, H69K, L89MA
 KN-19KN-19JQ616918None  L33FT12S, I13V, K14R, E35D, M36I, R41K, R57K, H69K, L89M, I93MA
Antoniadou (2013)GR029GR029KF671764None  L33FI13V, E35D, M36I, R41K, K45R, R57K, L63S, E65D, H69K, K70R, L89M, I93LA
Frentz (2013)EHR-20653EHR-20653JX299879None  L33FI13V, K14R, E35D, M36I, P39PL, R41K, L63T, C67E, H69K, V77I, L89M, I93LA
Hassan (2013)RS09000855RS09000855HQ441600None  L33FT12V, I13V, M36I, R41K, R57K, G68E, H69K, L89MA
 RS09000856RS09000856HQ441601None  L33FI13V, E35D, M36I, N37D, R41K, R57K, I64IT, H69K, L89MA
Kiptoo (2013)SNH072SNH072KC516965None  L33FI13V, K14R, E35D, M36I, R41K, R57K, G68E, H69K, K70R, L89M, I93IVA
Rusine (2013)705H705HKC841730None  V11VI, L33FI13V, K14R, M36I, R41K, R57K, H69KQ, L89MA
 444H444HKC841694None  L33FI13V, K20KR, M36I, P39S, R41K, H69K, I85IV, L89M, L97LIA
Van Zyl (2013)1196836KC424307None  L33FI13V, K20R, M36I, R41K, D60E, Q61E, H69K, L89M, I93VA