<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L33F
Rx PI-naive
IncludeMixtures No
References 40
Patients 65
Isolates 65
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Cornelissen (1997)92RW00892RW008AF009407None  L33FI13V, K14R, E35D, R41K, K45R, R57K, H69K, L89MA
Becker-Pergola (2000)171.005BPG171-005AF177351None  L33FI13V, E35D, M36I, R41K, K45R, R57K, G68E, H69K, L89MA
Eshleman (2001)SE660SE660AF388111None  L33FI13V, E35D, M36I, R41K, R57K, H69K, L89MA
 SE655SE655AF388110None  L33FI13V, K14R, E35D, M36I, R41K, R57K, H69K, L89MA
Koch (2001)NK-18NK-18AY007747None  L33FL10I, I13V, K14R, K20R, M36I, R41K, R57K, L63V, H69Q, K70R, L89MA
Servais (2004)SJ_Pat33SJKLM042AJ412962None  L33FI13V, K14R, I15V, G16E, K20I, E35D, M36I, R41K, R57K, H69K, L89MA
Yang (2004)99KE59199KE591AY492781None  L33FI13V, E35D, M36I, N37D, R41K, R57K, E65D, H69K, L89MA
Brown (2005)BB_92UG_02992UG_029AY713407None  L33FI13V, E35D, M36I, R41K, K45R, R57K, Y59H, H69K, L89MA
Razafindratsimandresy (2006)RR_MAD-TI058MAD-TI058DQ345017None  L33FI13V, K14R, K20I, E35D, M36I, R41K, K45R, R57K, L63P, C67Y, H69K, K70R, L89MA
Church (2007)133750R133750REF612185None  L33FI13V, E35D, M36I, R41K, R57K, H69K, L89MA
Galluzzo (2007)23340RW_23340JQ220047None  L33FI13V, K14R, Q18QH, E35D, M36I, R41K, R57K, H69K, K70KR, V77VI, L89MA
Razafindratsimandresy (2007)1414HIV-SEYEF143506None  L33FI13V, G16GE, K20R, M36I, R41K, R57K, H69K, K70R, L89MA
von Wyl (2007)15766307EF449883None  L33FI13V, K14R, I15V, G16E, E35D, M36I, R41K, K45R, R57K, H69K, L89MA
Balode (2010)S2303S2303GU945173None  L33FI13V, K14R, E35D, M36I, P39PL, R41K, L63T, C67E, H69K, V77I, L89M, I93LA
Hattori (2010)C05-2066263C05-2066263AB864008None  L33FI13V, E35D, M36I, R41K, R57K, E65D, H69K, R87K, L89MA
Mosha (2010)S5polS5polJQ071453None  L33FI13V, K14R, M36I, R41K, K45R, R57K, H69Q, L89MA
von Wyl (2010)2267214922672149GQ848156None  L33FI13V, E35D, M36I, P39AITV, R41K, R57K, I62V, L63S, I64V, C67CS, H69K, L89MA
Hamers (2011)CP076301540CP076301540HQ993583None  L33FI13V, K14R, M36I, R41K, R57K, E65ED, H69K, L89MA
 CP076301591CP076301591HQ993629None  L33FL10V, E35D, M36I, N37D, R41K, K45R, R57K, Q61H, L63P, H69K, I72IT, I85V, L89MA
 CP076302282CP076302282HQ993832None  L33FI13V, K14R, E35D, M36I, P39PS, R41K, R57K, H69K, L89MA
 CP076302304CP076302304HQ993850None  L33FL10V, I13V, K14R, E35D, M36I, N37D, R41K, K45R, R57K, Q61E, L63LAPV, C67Y, H69K, V77VI, L89MA
 CP076303070CP076303070HQ995250None  L33FI13V, E35D, M36I, R41K, R57K, H69K, L89MA
 CP076303104CP076303104HQ995280None  L33FI13V, M36I, R41K, R57K, I62V, L63S, H69K, L89MA
 CP076301996CP076301996HQ995450None  L33FI13V, M36I, R41K, E65D, H69K, V77I, L89MA
 CP076302011CP076302011HQ995453None  L33FI13V, K20R, E35D, M36I, R41K, R57K, H69K, L89MA
Ndembi (2011)AICPS283AICPS283HQ702652None  L33FI13V, E35D, M36I, R41K, I62V, L63P, I64L, H69K, K70R, L89M, F99LA
 AICPS001AICPS001HQ702677None  L33FI13V, K14R, G17D, E35D, M36T, R41K, R57K, L63V, E65D, H69K, V77I, L89MA
Yang (2011)KN-12KN-12JQ616914None  L33FT12S, I13V, K14R, E35D, M36I, N37D, R41K, R57K, I62IV, E65D, H69K, L89MA
 KN-19KN-19JQ616918None  L33FT12S, I13V, K14R, E35D, M36I, R41K, R57K, H69K, L89M, I93MA
Nazziwa (2012)10116011011601JX498971None  L33FI13V, M36I, R41K, R57K, H69K, L89MA
Ndase (2012)5213507052135070KC900539None  L33FI13V, M36I, P39S, R41K, R57K, E65D, H69K, L89MA
 5803920258039202KC900564None  L33FI13V, E35D, M36I, R41K, R57K, C67E, H69K, I72V, L89MA
 5208551252085512KC900632None  L33FI13V, M36I, P39S, R41K, R57K, E65D, H69K, L89MA
 5213138052131380KC900538None  L33FI13V, M36I, P39S, R41K, R57K, E65D, H69K, L89MA
 5805601258056012KC900627None  L33FI13V, E35D, M36I, R41K, R57K, C67E, H69K, I72V, L89MA
 5301549253015492KC900659None  L33FI13V, K14R, E35D, M36I, N37D, R41K, R57K, H69K, K70R, V77VI, L89MA
 5805449258054492KC900600None  L33FI13V, E35D, M36I, R41K, R57K, C67E, H69K, I72V, L89MA
 5206508252065082KC900692None  L33FI13V, K14KR, M36I, R41K, K43KR, R57K, E65D, H69K, L89MA
Sigaloff (2012)KELKN266KELKN266JN628524None  L33FI13V, K14R, E35D, M36I, R41K, R57K, L63V, H69K, L89M, L97IA
Antoniadou (2013)GR029GR029KF671764None  L33FI13V, E35D, M36I, R41K, K45R, R57K, L63S, E65D, H69K, K70R, L89M, I93LA
Frentz (2013)EHR-20653EHR-20653JX299879None  L33FI13V, K14R, E35D, M36I, P39PL, R41K, L63T, C67E, H69K, V77I, L89M, I93LA
Hassan (2013)RS09000855RS09000855HQ441600None  L33FT12V, I13V, M36I, R41K, R57K, G68E, H69K, L89MA
 RS09000856RS09000856HQ441601None  L33FI13V, E35D, M36I, N37D, R41K, R57K, I64IT, H69K, L89MA
Kiptoo (2013)SNH072SNH072KC516965None  L33FI13V, K14R, E35D, M36I, R41K, R57K, G68E, H69K, K70R, L89M, I93IVA
Rusine (2013)705H705HKC841730None  V11VI, L33FI13V, K14R, M36I, R41K, R57K, H69KQ, L89MA
 444H444HKC841694None  L33FI13V, K20KR, M36I, P39S, R41K, H69K, I85IV, L89M, L97LIA
Van Zyl (2013)O1196836KC424307None  L33FI13V, K20R, M36I, R41K, D60E, Q61E, H69K, L89M, I93VA
Hassan (2014)RS09000753RS09_753KC568476None  L33FL10V, L19R, K20R, M36I, N37D, R41K, R57K, H69K, L89MA
Khairunisa (2014)TD42TD42KM212915None  L33FI13V, M36I, P39L, R41K, K55R, H69K, K70R, I72T, L89MA
Lee (2014)AMU034AMU034KJ906654None  L33FI13V, E35D, M36I, R41K, R57K, H69K, L89MA
 MBA1308MBA1308KJ906997None  L33FI13V, E35D, M36I, R41K, K45R, R57K, H69Q, I72IV, L89MA
 MBA1152MBA1152KJ906850None  L33FT12P, I13V, K14R, E35D, M36I, R41K, K45R, R57RK, L63LIPT, G68E, H69K, K70R, L89MA
Wallis (2014)4151741517KM458599None  L33FE35D, M36I, R41K, K45R, R57K, C67CG, H69K, L89MA
Budambula (2015)MK122MK122KP792116None  L33FI13V, M36I, R41K, R57K, G68E, H69K, L89MA
 MK101MK101KP792095None  L33FR41K, H69K, L89MA
Dauwe (2015)A1_11001A1_11001KT863593None  L33FI13V, K14R, Q18H, M36I, R41K, R57K, H69K, L89MA
Kotaki (2015)DN9DN9KJ865352None  L33FL10I, I13V, M36I, P39L, R41K, K45R, H69K, K70R, I72T, L89MA
 UA15UA15KJ865339None  L33FI13V, K20R, M36I, P39S, R41K, I62V, L63P, G68E, H69K, K70R, L89IA
Meini (2015)109266109266KM438248None  L33FI13V, G16E, E35D, M36I, R41K, R57K, L63A, H69K, L89MA
Chow (2016)MYNBB192MYNBB192KU536032None  L33FG16E, E35D, M36I, R41K, K45R, I62V, L63P, H69K, K70R, A71V, L89M, I93L, L97IA
 MYNBB206MYNBB206KU536042None  L33FG16E, E35D, M36I, R41K, K45R, I62V, L63P, H69K, K70R, L89M, I93L, L97IA
Gashnikova (2016)Tyumen26Tyumen26KX640138None  L33FI13V, M36I, R41K, L63LI, G68E, H69K, L89M, I93LA
Ndahimana (2016)14251425KU922785None  L33FL10V, I13V, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
 968968KU922768None  L33FV11A, I13V, E35D, M36I, R41K, R57K, I62V, C67Y, H69K, L89MA
Zeh (2016)0513800_040513800_04KU248597None  L33FE35D, R41K, R57RK, H69K, K70R, V77VI, L89MA