<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L33F
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 21
Isolates 22
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Weidle (2001)PW_UG4399PW_UG4399a RTV69V82AL33FL10V, I13V, K20R, E35D, M36I, R41K, R57K, C67Y, H69K, L89MA
Non-B Workgroup (2005)TK3001TK3001 SQV90L90ML33FI13V, K14R, K20T, M36I, R41K, K43N, R57K, H69K, V82I, I85V, L89MA
Weber (2005)M41984M41984AY677484IDV139 L33FI13V, K14R, E35D, M36I, R41K, K43KR, R57K, H69K, L89MA
Baxter (2006)12-20242024-30709DQ876698PINAM46L, I54VL33F, N83DL10V, I13V, K14R, E35D, M36IL, N37ND, R41K, R57K, H69Q, L89MA
 48-12021202-30702DQ877746PINAI54V, V82A, L90ML33F, N83DI13V, G16E, K20R, E35D, M36I, N37D, R41K, R57RK, L63N, H69K, K70R, L89I, T91V, I93LA
 48-12041204-30709DQ877748PINAM46I, G48Q, I54T, V82FL33F, Q58E, N83DL10V, I13V, G16E, E35D, M36L, P39S, R57K, I62V, L63V, H69K, T74A, L89MA
 48-12541254-30617DQ877779PINAG48VL33F, N83DL10LI, I13V, E35D, M36V, N37NS, P39T, R41K, R57K, L63S, H69K, L89MA
  1254-40601DQ877780PI, RTV, TPV>50 L33FT12A, I13V, E35D, M36IV, P39AT, R41K, R57K, L63S, H69K, L89MA
 48-50215021-30606DQ878555PINAI54V, V82F, I84IV, L90ML33F, F53LL10I, V11L, I13V, I15V, G16E, L19P, K20I, E35N, M36I, K45V, L63T, H69K, L89MA
 48-50735073-30807DQ878583PINAI54V, V82A, L90ML33F, T74TPT4TS, I13V, K20R, E35D, M36I, N37D, R41K, F53I, I62IV, I66IF, H69R, L89IA
 48-50775077-30903DQ878587PINAM46L, I54V, V82AL24I, L33F, F53L, T74PL10I, I13V, L19I, K20R, E35D, M36I, N37D, Q61R, L63P, H69K, L89MA
Kouri (2012)CU1908-09CU1908-09JQ585320PINAM46I, I54V, V82F, L90ML33F, T74PK20I, E35N, M36I, R41K, K43R, F53Y, R57K, I62V, L63P, H69K, I85V, R87RK, L89MA
Avidor (2013)196196 APV M46I, I84VL10FI, L33FI13V, K20R, L24LV, E35D, M36I, N37D, R41K, K45R, R57K, I62IV, H69K, L89M, I93VA
Van Zyl (2013)O11961593KC423255LPV52 L33FI13V, K20R, M36I, R41K, D60E, Q61E, H69K, L89M, I93VA
Acharya (2014)DGP185DGP185KJ185355RTV, ATV M46I, I54V, V82A, N88SL24I, L33F, Q58EL5I, L10V, I13V, I15V, E35D, M36I, N37E, R41K, R57K, D60E, H69K, A71V, L89MA
Kolomeets (2014)307307_405KJ870500APV  L33F, F53FLL10LI, K14R, G16E, K20R, E35D, M36I, R41K, H69K, L89M, I93LA
 316316_419KJ870510APV  L33F, T74PI13V, K14R, E34EG, E35D, M36I, R41K, R57RK, D60DE, I62IT, L63LI, H69K, V77I, L89M, I93LA
 193193_342KJ870451APV I47IVL33F, F53LI13V, I15V, K20T, E35D, M36I, R41K, H69K, V77I, L89MA
Nerrienet (2014)U0407179U0407179JN675767LPV M46I, I84V, L90ML10F, L33F, F53L, Q58E, G73GS, N88G, L89VI13V, K20T, E35D, M36I, R41K, K55R, R57K, L63P, I66IF, H69K, A71VA
 U0907156U0907156JN675771LPV V32I, M46I, I47V, I54M, L90ML33F, Q58E, N83DL10V, I13V, G16A, M36I, N37D, R41K, K55R, D60N, L63P, I64V, H69K, K70R, A71IV, G73GD, L89IA
Ndahimana Jd Riedel (2016)20292029KT982523LPV I54V, V82VAL33F, T74PL10I, I13V, E35D, M36I, R41K, R57K, L63T, H69K, V77I, L89MA
 21652165KT982498LPV M46I, I54V, V82AL10F, L33FI13V, E35D, M36I, N37D, P39Q, R41K, K45I, R57K, D60NS, Q61E, L63P, H69Q, L89I, T91SA