<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation K20T
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 11
Isolates 12
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Shafer (2003)A384_09830983bEF548169NFV43  L10V, I13V, K20T, E35D, M36I, R41K, R57K, H69K, L89M, I93MA
Non-B Workgroup (2005)UK1516UK1516 PI, LPVNAI54L L10I, I13V, G16E, K20T, E35D, M36I, R41K, R57K, L63T, H69K, T74S, V82VI, I85V, L89MA
 TK3001TK3001 SQV90L90ML33FI13V, K14R, K20T, M36I, R41K, K43N, R57K, H69K, V82I, I85V, L89MA
 TK3029TK3029 SQV, NFV149L90M L10V, I13V, K20T, E35D, M36I, R41K, H69K, T74S, L89IA
 TK5002TK5002 NFV189N88SL10FI13V, K14R, I15V, K20T, E35D, M36I, R41K, K45R, R57K, H69K, L89IA
Weber (2005)F51354F51354AY677444SQV, NFV115  L10V, I13V, K14R, G16E, K20T, E35D, M36I, R41K, R57K, L63T, H69K, I72T, T74TA, L89MA
Baxter (2006)12-21202120-30715DQ876783PINAM46I, I47V, L90ML10F, L33I, F53L, G73GS, N88G, L89VI13V, K14R, K20T, E35D, M36I, R41K, R57K, I62V, L63P, H69K, A71IA
  2120-40510DQ876754PI, RTV, TPV>43M46I, I47V, L90ML10F, L33I, F53L, G73S, N88G, L89VI13V, K14R, K20T, E35D, M36I, R41K, R57K, I62V, L63P, H69K, A71IA
Dau (2010)11741A11741AGU582052PINAN88SL10F, L89VI13V, K20T, E35D, M36I, R41K, I62V, L63P, H69K, T74SA
Dvali (2012)R005R005FJ456894NFV M46MI, N88NSL23LI, K43KTK14R, I15IV, K20T, E35D, M36I, N37D, R41K, L63P, H69K, A71AV, L89M, I93LA
Kouri (2012)CU737-10CU737-10JQ585413PINAV32I, M46I, I47V, L90ML33F, F53L, L89VR8G, I13V, K20T, E35D, M36I, R41K, H69K, G73D, V82IA
Avidor (2013)989_MT989_MTKC184397NFV L90ML10LFI13V, K20T, E35D, M36I, R41K, H69K, A71AV, T74S, L89I, I93LA