<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation K20I
Rx PI-naive
IncludeMixtures No
References 66
Patients 143
Isolates 146
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Cornelissen (1997)92UG05992UG059AF009403None   I13V, G16E, L19W, K20I, M36I, R41K, H69K, L89MA
Eshleman (2001)SE173SE173AF388137None   T12TA, I13V, K14R, I15V, G16E, K20I, E35D, M36I, R41K, H69K, L89MA
 SE702SE702AF388114None   I13V, G16E, K20I, E35D, M36I, R41K, H69K, L89MA
 SE653SE653AF388109None   T12I, I13V, K14KR, I15V, G17E, K20I, E35D, M36I, R41K, R57K, L63S, I64L, H69K, L89MA
Toni (2003)TTDdp10TTDdp10AY207662None   L10I, I13V, K14R, I15V, G16E, K20I, E35D, M36I, R41K, H69K, L89MA
Wilbe (2003)UG266UG266AY352657None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, L89MA
Servais (2004)SJ_Pat33SJKLM042AJ412962None  L33FI13V, K14R, I15V, G16E, K20I, E35D, M36I, R41K, R57K, H69K, L89MA
Arien (2005)VI75VI75DQ177223None   I13V, K14R, K20I, E35D, M36I, R41K, K45R, H69K, L89MA
K'Aluoch (2005)OK_TC024604TC024604DQ079826None   L10I, L19P, K20I, M36I, R41K, H69K, L89MA
Weber (2005)F54577F54577AY677382None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, H69K, V82I, L89MA
Marechal (2006)JF_099JF_099DQ443691None   L10I, T12A, I13V, K14R, I15IV, G16E, K20I, E35N, M36I, P39S, R41K, R57K, L63S, E65D, I72V, P79PH, L89MA
Razafindratsimandresy (2006)RR_MAD-TI058MAD-TI058DQ345017None  L33FI13V, K14R, K20I, E35D, M36I, R41K, K45R, R57K, L63P, C67Y, H69K, K70R, L89MA
Vidal (2006)NV_KBS18702.KBS187AM041032None   T12S, I13V, G17E, K20I, E35D, M36I, N37Q, H69K, L89MA
 NV_KSS01302.KSS013AM041049None   L10M, I13V, K14R, G16A, K20I, E35D, M36I, R41K, R57K, H69K, K70R, L89MA
 NV_KSTB00702.KSTB007AM040992None   I13V, K14R, K20I, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
Baker (2007)1354KP02-1354KPAY803460None   L10I, I13V, K20I, E35N, M36I, R41K, H69Q, L89MA
 9073NR03-9073NRAY803461None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, L89MA
 300NG01-300NGAY803462None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, T74S, L89MA
 TC0251TC025104AY803485None   T12A, I13V, K20I, E35D, M36I, R41K, Q61N, I64M, H69K, L89MA
 P0034P0034-090205EF186134None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, L89MA
 P0218P0218-130705EF186146None   I13V, K20I, E35D, M36I, R41K, H69K, L89MA
 A1025MBA1025-180805EF186206None   L10I, I13V, K14R, I15V, K20I, E35D, M36I, R41K, R57K, L63S, H69K, L89MA
 AR016MBAR016-020505EF186225None   I13V, K20I, E35D, M36I, R41K, R57K, D60E, C67A, H69K, L89MA
 AR019MBAR019-260505EF186227None   I13V, K20I, M36I, H69K, L89MA
Brumme (2007)1365PRRT_1365EF368675None   I13V, K14R, K20I, M36I, R41K, H69K, V82I, L89MA
Church (2007)653-134024g653EF612097None   T12I, I13V, K14KR, I15V, G17E, K20I, E35D, M36I, R41K, R57K, L63PS, I64L, H69K, L89MA
 702-136536A702EF612115None   I13V, G16E, K20I, E35D, M36I, R41K, H69K, L89MA
Gatanaga (2007)C04-5555-5799-1C04-5555-5799-1AB640397None   I13V, K20I, E35D, M36I, R41K, I62IV, H69K, T74S, L89MA
 C04-5555-5800-1C04-5555-5800-1AB640398None   I13V, K20I, E35D, M36I, R41K, H69K, T74S, L89M, I93LA
McNulty (2007)Cam32Cam32PLDQ869193None   L10I, I13V, G16E, K20I, E35D, M36I, L63GISV, H69K, L89MA
  Cam32DBSDQ869192None   L10I, I13V, G16E, K20I, E35D, M36I, L63GISV, H69K, L89MA
von Wyl (2007)1234924217EF449976None  V11VIL10I, I13V, K14KR, I15V, G16E, K20I, E35D, M36I, R41K, K43R, R57RK, L63LH, H69Q, K70KR, I72V, L89MA
Ndembi (2008)IAEM031IAEM031EU306763None   I13V, K14R, K20I, M36I, R41K, L63P, H69K, L89MA
 IAEM078IAEM078EU306794None   I13V, K14KR, I15V, K20I, E35D, M36I, R41K, I64M, H69K, L89MA
Nyombi (2008)TBK018TBK018EU251725None   I13V, K20I, E35D, M36I, R41K, R57K, L63P, H69K, I72L, V82I, L89MA
Avi (2009)N32N32FJ154015None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, L89MA
Bartolo (2009)CSE11801AOCSE118EU068201None  V11IL10I, I13V, I15V, G16E, K20I, E35D, M36I, N37K, R41K, L63T, H69Q, L89M, I93LA
 HJM0601AOHJM06EU068249None   T12K, I13V, K14R, G16E, K20I, E35D, M36I, H69K, I72V, V77I, L89MA
 LFA9001AOLFA90EU068271None   L10I, I13V, K20I, E35D, M36I, L63T, H69K, L89MA
 SNS2201AOSNS22EU068291None   I13V, G16E, L19I, K20I, E35D, M36I, R41K, H69K, K70R, V77I, L89MA
 SNS4901AOSNS49EU068304None   L10I, I13V, K20I, E35D, M36I, L63T, H69K, L89MA
 HM18901AOHM189EU068327None   I13V, K14R, G16E, K20I, E35D, M36I, R41K, H69K, K70R, V77I, L89MA
Eshleman (2009)K35135R908-101587FJ389132None   I13V, K14R, K20I, E35D, M36I, R41K, L63P, H69K, L89MA
Vercauteren (2009)pt2162245005610GQ398862None   L10I, T12R, I13V, I15V, L19I, K20I, E35D, M36I, N37D, R41K, H69Q, V82I, L89MA
 pt16993158547710GQ399325None   L10LI, I13V, K14R, G17GE, K20I, M36I, N37D, H69K, L89MA
 pt13285252073064GQ399696None   I13V, K14GR, K20I, M36I, H69K, L89MA
Castelbranco (2010)090017A090017AHM357744None   I13V, K14NS, G16E, K20I, E35D, M36I, R41K, H69K, K70KR, V77I, L89MA
Ndembi (2010)DT0010_05_P110GQ409593None   I13V, I15V, K20I, E35D, M36I, R41K, I62V, L63P, I64M, G68E, H69R, L89MA
 DT3482_05_P13482GQ409617None   I13V, K14R, G16E, K20I, M36I, R41K, H69K, L89MA
Towler (2010)2436546-PHM037826None   I13V, K14R, K20I, M36I, P39Q, R41K, L63P, H69K, L89MA
  519810-RHM037891None   I13V, K14R, K20I, M36I, P39Q, R41K, L63P, H69K, L89MA
Aghokeng (2011)SK9027-PISK9027-PIHQ864373None   I13V, G17E, K20I, E35D, M36I, R57K, D60E, L63P, H69K, L89MA
El Annaz (2011)1732217322HQ393322None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, L89MA
Hamers (2011)CP076301755CP076301755HQ993744None   L10IV, I13V, I15V, Q18QH, L19I, K20I, E35D, M36I, R41K, R57K, L89MA
 CP076303567CP076303567HQ994039None   L10I, I13V, K14R, I15V, G16E, K20I, E35D, M36I, R41K, L63A, H69Q, L89MA
 CP076300716CP076300716HQ994922None   I13V, K14R, K20I, E35D, M36I, R41K, L63T, I64M, H69K, L89MA
 CP076301853CP076301853HQ994994None   T12A, I13V, I15V, K20I, M36I, R41K, L63P, H69K, L89MA
 CP076301873CP076301873HQ995005None   I13V, K20I, E35D, M36V, R41K, R57K, L63P, H69K, L89MA
 CP076302055CP076302055HQ995022None   I13V, K14R, K20I, E35D, M36I, R41K, L63T, H69K, T74S, L89MA
 CP076303076CP076303076HQ995254None   I13V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MA
 CP076300714CP076300714HQ995316None   I13V, K20I, E35D, M36I, R41K, H69K, V77VI, L89MA
 CP076300763CP076300763HQ995335None   I13V, G16E, K20I, E35D, M36I, R41K, R57K, D60E, H69K, L89MA
 CP076300769CP076300769HQ995338None   I13V, G16E, K20I, E35D, M36I, R41K, L63LP, H69K, K70R, V75I, L89MA
 CP076301924CP076301924HQ995395None   I13V, K14R, G16E, K20I, E35D, M36I, R41K, K45R, R57K, L63P, H69K, L89MA
 CP076301930CP076301930HQ995398None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63A, H69K, V82VI, L89MA
 CP076302904CP076302904HQ995473None   I13V, G16E, K20I, E35D, M36I, R41K, H69K, K70KR, I72V, L89MA
 CP076302905CP076302905HQ995474None   I13V, K20I, E35D, M36I, R41K, H69K, V77VI, L89MA
Ndembi (2011)NTCPS716NTCPS716HQ702631None   I13V, K14R, K20I, E35D, M36I, N37S, R41K, L63A, H69K, K70Q, L89MA
 AICPS495AICPS495HQ702640None   I13V, K20I, E35D, M36I, R41K, R57K, D60E, L63P, H69K, T74A, L89MA
 AICPS336AICPS336HQ702650None   I13V, K20I, E35N, M36I, R41K, H69K, V77I, L89MA
Caron (2012)Gab021296Gab021296HQ541947None   I13V, K14R, G16E, L19I, K20I, E35D, M36I, N37K, R41K, H69K, L89MA
Dvali (2012)R154R154GQ268528None   I13V, K14R, K20I, M36I, R41K, H69K, L89MA
Karlsson (2012)SE_185SE_185JQ698793None   I13V, K14S, K20I, E35D, M36I, R57K, L63T, I64L, H69K, I72T, T74S, L89MA
Nazziwa (2012)50463025046302JX499002None   I13V, K14R, G16A, K20I, E35D, M36I, R41K, H69K, L89MA
 51376305137630JX499010None   I13V, K20I, E35D, M36I, N37S, R41K, R57K, H69K, T74S, L89MA
Ndase (2012)5500571255005712KC900763None   I13V, K14KR, K20I, E35D, M36I, R41K, I64V, H69K, L89MA
 5507327255073272KC900547None   I13V, K14R, K20I, E35ED, M36I, R41K, L63P, H69K, L89MA
Reynolds (2012)J7227J7227-0JN652166None   I13V, I15IV, K20I, E35N, M36I, P39PT, R41K, H69K, V77IM, L89MA
  J7227-1JN652202None   I13V, K20I, E35N, M36I, R41K, H69K, V77I, L89MA
Sigaloff (2012)KELKN251KELKN251JN628514None   I13V, L19P, K20I, E35D, M36I, R41K, K45R, R57K, L63S, E65D, H69K, V77I, L89MA
 KELKN252KELKN252JN628515None   I13V, L19P, K20I, E35D, M36I, R41K, K45R, R57K, L63S, E65D, H69K, L89MA
Ssemwanga (2012)RCC_TDR_358561RCC_TDR_358561JQ266029None   I13V, K14R, K20I, E35D, M36I, R41K, L63P, H69K, L89M, I93VA
Ssemwanga (2012)3272HR3272HRJF800198None   I13V, K20I, E21K, M36I, R41K, L63N, H69K, V82I, L89MA
Youngpairoj (2012)cm8bbcm8bbDQ166432None   L10I, I13V, G16E, K20I, E35D, M36I, L63V, H69K, L89MA
Aghokeng (2013)HJ3031HJ3031JX983024None   L10I, I13V, I15L, G16E, L19P, K20I, L33V, M36I, R41K, L63I, H69K, L89MA
Antoniadou (2013)GR064GR064KF671786None   L10I, I13V, K14R, G16E, K20I, E35D, M36I, R41K, K45R, R57K, D60E, L63P, H69Q, L89MA
 GR083GR083KF671797None   L10I, I13V, I15V, G16E, L19V, K20I, E35D, M36I, P39PLS, R57K, L63AT, E65ED, H69K, T74S, L89M, T91TIA
Brooks (2013)CAN2013-094CAN13-094KF727733None   T12TA, I13V, K14KR, I15V, K20I, E35D, M36I, R41K, L63PS, H69K, I72M, L89MA
Frentz (2013)EHR-01921EHR-01921JX299577None   L10I, I13V, K14R, I15V, G16E, L19P, K20I, E35N, M36I, R41K, K45R, R57K, L63S, H69K, K70R, L89MA
 EHR-13657EHR-13657JX299764None   I13V, K14R, G17E, K20I, L33V, E35N, M36I, R41K, D60E, L63P, H69K, T74S, L89MA
 EHR-96853EHR-96853JX301133None   P1T, I13V, K14R, I15V, K20I, E35D, M36I, R41K, I64M, H69K, L89MA
Hassan (2013)RS09000857RS09000857HQ441602None   I13V, K20I, E35D, M36I, R41K, H69K, L89MA
Kemal (2013)77177717JQ364523None   I13V, K14N, G16E, L19I, K20I, E35D, M36I, K45R, R57K, L63H, H69K, L89MA
Kiertiburanakul (2013)R71TS114R71TS114KC921592None   V11C, T12H, I13A, K20I, E35D, M36I, R41K, R57K, H69K, L89MA
Nzeyimana (2013)102_1039102_1039HG780761None   L10I, I13V, I15IV, G16A, K20I, E35D, M36I, R41K, H69Q, L89MA
Pircher (2013)B1109B1109JX110296None   T12S, I13V, G17E, L19I, K20I, E35N, M36I, I62V, L63P, H69K, K70N, I72V, V77I, L89MA
Rusine (2013)759H759HKC841770None   L10LM, I13V, K20I, E35N, M36I, P39Q, R41K, K45R, R57K, Y59H, Q61N, L63P, H69KQ, I72IM, V77I, L89MA
 703H703HKC841728None   I13V, K14R, K20I, M36I, R41K, L63LP, H69K, K70KR, L89MA
 408H408HKC841668None   T12A, I13V, K20I, M36I, R41K, K45R, Q61E, L63S, H69K, L89MA
 733H733HKC841754None   I13V, K14R, G16E, K20I, E35N, M36I, R41K, I64M, H69Q, I72V, L89MA
Sigaloff (2013)JCR017_0JCR017_0JX181984None   I13V, K14R, K20I, M36I, R41K, H69K, L89MA
Bartolo (2014)09AOHDP9309AOHDP93KF853888None   T12P, I13V, K14KR, G16E, L19LV, K20I, E35DN, M36I, R41K, H69K, K70R, I72IT, V77VI, L89MA
 09AOHDP25009AOHDP250KF853824None   I13V, G16E, L19I, K20I, E35D, M36I, R41K, R57K, L63H, H69K, K70R, V77I, L89MA
 09AOHDP4809AOHDP48KF853862None   I13V, K14R, G16GE, K20I, A22D, D25A, E35D, M36I, R41K, H69K, K70R, V77I, L89MA
 09AOHDP15609AOHDP156KF853774None   I13V, K14R, G16E, K20I, E35D, M36I, N37S, R41K, H69K, K70E, V77I, T80P, L89MA
Hassan (2014)RS11000370RS11_370KC568501None   L10I, T12R, I13V, I15V, G16E, L19I, K20I, E35D, M36I, R41K, R57K, H69K, L89MA
Lee (2014)MBA1249MBA1249KJ906943None   I13V, K14R, K20I, E35D, M36I, R41K, L63P, H69K, K70KR, L89MA
 MBA1291MBA1291KJ906982None   I13V, K14R, K20I, E35D, M36I, R41K, L63P, H69K, L89MA
 MBA1083MBA1083KJ906783None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, L89MA
 MBA1471MBA1471KJ907149None   L10I, I13V, K14R, G16E, K20I, E35D, M36I, R41K, I64IV, H69K, K70R, L89MA
 MBA1363MBA1363KJ907049None   I13V, K14R, K20I, E35ED, M36I, R41K, K43KR, Q61QH, L63PS, I64IM, H69K, L89MA
 MBA1251MBA1251KJ906945None   I13V, K20I, E35D, M36I, R41K, L63P, G68E, H69R, L89MA
 MBA1403MBA1403KJ907088None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, L89MA
 MBA1430MBA1430KJ907113None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MA
 MBA1455MBA1455KJ907134None   I13V, L19I, K20I, M36I, R41K, I64IM, L89MA
 MBA1029MBA1029KJ906732None   I13V, K14R, K20I, L23LV, E35D, M36I, R41K, H69K, K70KR, V82I, L89MA
 MBA1418MBA1418KJ907103None   I13V, K14KR, L19IM, K20I, E35N, M36I, R41K, H69K, L89MA
 MBA1269MBA1269KJ906961None   I13V, G16E, K20I, E35D, M36I, P39Q, R41K, L63H, H69K, K70R, V77I, L89MA
 MBA1437MBA1437KJ907119None   I13V, G16GE, K20I, E35DN, M36I, R41K, H69K, L89MA
 MBA1002MBA1002KJ906707None   I13V, K14R, K20I, E35D, M36I, P39Q, R41K, L63P, H69K, V82VI, L89MA
 MBA1233MBA1233KJ906927None   I13V, G16GE, K20I, E35D, M36I, R41RK, I64L, H69K, L89MA
 AMU009AMU009KJ906633None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MA
 MBA1473MBA1473KJ907151None   I13V, K14R, G16E, K20I, E35N, M36I, R41K, L63LI, H69K, V77VIM, L89MA
 MBA1413MBA1413KJ907098None   I13V, K20I, E35D, M36I, R41K, R57K, L63P, H69K, L89MA
 MBA1383MBA1383KJ907069None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, L89MA
 MBA1284MBA1284KJ906975None   I13V, K14KR, G16GE, K20I, E35D, M36I, R41K, H69K, L89MA
 MBA1246MBA1246KJ906940None   I13V, K14R, K20I, E35D, M36I, R41K, L63P, H69K, L89MA
 MBA1086MBA1086KJ906786None   I13V, K20I, E35D, M36I, R41K, I64IM, H69K, L89MA
Meixenberger (2014)11-0017611-00176KJ771465None   I13V, L19P, K20I, E35D, M36I, R41K, L63P, H69K, L89MA
Bruzzone (2015)HM0122FHM0122FEU914164None   K14R, G16A, K20I, E35D, M36I, R41K, K45RT, R57K, H69K, I72V, L89MA
 HM0050FHM0050FEU914160None   T12P, I13V, K14R, G16A, K20I, E35D, M36I, R41K, K45R, R57K, L63P, G68E, H69K, I72V, L89MA
Budambula (2015)MK38MK38KP792032None   I13V, K14R, K20I, E35D, M36I, R41K, K45R, R57K, Q61H, I64M, H69K, I72E, V82I, L89MA
Cheriro (2015)NLHG-135NLHG-135KT370885None   I13V, G16A, K20I, E35ED, M36I, R41K, H69K, I72IM, L89MA
Dauwe (2015)iH_07089iH_07089KT863912None   I13V, K14R, G16E, K20I, E35D, M36I, N37E, R41K, H69K, K70R, V77I, L89MA
Sutherland (2015)99_PREKT351847None   I13V, K20I, E35D, M36I, R41K, H69R, L89MA
 44_PREKT351837None   I13V, K14KR, K20I, E35N, M36I, R41K, H69K, V77VI, L89MA
Boillot (2016)VIR10VIR10KT315988None   L10I, I13V, K14R, G17E, K20I, E35D, M36I, R41K, K45R, I64M, H69Q, L89MA
 MAK01MAK01KT315964None   I13V, K14R, G16E, L19I, K20I, E35D, M36I, R41K, H69K, L89MA
 VIR09VIR09KT315987None  V11IL10I, I13V, K14KR, I15V, G16GE, K20I, E35DN, M36I, R41K, L63S, H69K, L89MA
Gashnikova (2016)Tyumen46Tyumen46KX640155None   I13V, I15V, L19I, K20I, E35D, M36I, R41K, Q61E, I64M, H69K, L89MA
Ndahimana (2016)14151415KU922788None   L10V, I13V, K14R, K20I, M36I, R41K, L63LP, I64IM, H69K, L89MA
 823823KU922832None   L10LIM, I13V, K20I, E35N, M36I, R41K, H69K, L89MA
Otecko (2016)410309410309KX306440None   I13V, K20I, E35D, M36I, R41K, D60E, H69K, L89MA
 408206408206KX306417None   T12I, K14R, I15V, G16E, K20I, E35N, M36I, R41K, K45R, R57K, L63S, I64M, H69K, L89MA
Pouran Yousef (2016)436211-00176KX467003None   I13V, L19P, K20I, E35D, M36I, R41K, L63P, H69K, L89MA
Onywera (2017)06206020620602KX791013None   L10V, I13V, G16E, K20I, E35D, M36I, N37D, R41K, R57K, H69K, K70R, T74K, L89MA