Protease Inhibitors

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Protease Inhibitors

Subtype	A
Gene	PR
Mutation	V11I
Rx	PI-naive
IncludeMixtures	No

References	11
Patients	17
Isolates	17

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	PIs	PIMinorDRMs	OtherMut	Subtype
Eshleman (2004)	225_692	225_692	AY444195	None	V11I	I13V, G16E, K20R, E35D, M36I, R41K, L63V, G68E, H69K, K70R, L89M, T91V, I93L	A
Vazquez de Parga (2005)	BL97002	BL97002	EU345609	None	V11I	I13V, K14R, E35D, M36I, R41K, I64V, H69K, L89M, I93L	A
	BL97004	BL97004	EU345611	None	V11I	L10I, I13V, K14R, E35D, M36I, R41K, I64V, H69K, L89M, I93L	A
	RU99011	RU99011	EU345784	None	V11I	I13V, K14R, G16E, L24F, E35D, M36I, R41K, I64V, H69K, L89I, I93L	A
Vidal (2006)	NV_KTB002	02.KTB002	AM041033	None	V11I	L10I, I13V, K14R, L19P, K20I, M36I, R41K, L63S, H69K, I72V, L89M	A
Bartolo (2009)	SNS106	01AOSNS106	EU068287	None	V11I	T12K, I13V, K14R, K20I, E35D, M36I, N37E, R41K, D60E, H69K, L89M	A
	SNS39	01AOSNS39	EU068300	None	V11I	L10I, T12R, I13V, I15V, L19I, M36I, N37D, R41K, H69Q, V82I, L89I	A
	HDC249	93AOHDC249	EU068314	None	V11I	T12E, I13V, K20I, E35D, M36I, N37S, R41K, H69K, K70R, L89M	A
	HDC250	93AOHDC250	EU068315	None	V11I	I13V, K14R, K20I, M36I, R41K, H69K, L89M	A
Vercauteren (2009)	pt623	9269506418	GQ400401	None	V11I	L10V, I13V, K14R, G16E, K20R, E35D, M36I, R41K, H69K, L89M	A
Djoko (2010)	634	CD4617	FR666634	None	V11I	I13V, G16E, E35D, M36I, R41K, R57K, H69R, K70R, L89M	A
Yang (2010)	2010693452	2010693452	JQ616891	None	V11I	L10I, T12K, I13V, L19V, M36I, N37D, R41K, I62V, L63A, H69Q, V82I, L89M	A
Charpentier (2011)	23	CP 001 2052		None	V11I	L10I, I13V, K20R, M36I, L63T, I64L, H69K, L89M	A
Hamers (2011)	CP076300874	CP076300874	HQ995131	None	V11I	I13V, G16A, M36I, R41K, R57K, L63V, H69K, L89M	A
Hassan (2012)	RS09000961	RS09000961	HQ441699	None	V11I	L10I, I13V, K14KR, I15IV, E35D, M36I, N37D, R41K, R57K, H69K, L89M	A
	RS11000256	RS11000256	JQ698355	None	V11I	L10I, I13V, E35D, M36I, R41K, R57K, I62V, L63S, I64L, H69K, L89M	A
Karlsson (2012)	SE_34	SE_34	JQ698689	None	V11I	I13V, K14R, I15V, G16GE, K20R, E35D, M36I, R41K, R57K, L63T, H69K, L89M	A

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