<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L10M
Rx PI-naive
IncludeMixtures No
References 23
Patients 24
Isolates 24
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Shafer (2003)A384_11541154aEF548989None   L10M, I13V, K14R, L19I, E35D, M36I, N37D, R41K, R57K, D60E, H69K, L89M, F99XA
Servais (2004)SJ_Pat31SJKLM041AJ412961None   L10M, I13V, G16E, E35N, M36I, P39S, R41K, H69K, K70R, P81PL, L89MA
Marechal (2006)JF_101JF_101DQ443692None   L10M, I13V, L33V, E35D, M36I, R41K, H69K, L89MA
Niama (2006)ARV80ARV80FM164887None   L10M, I13V, K20IV, E35D, M36I, R41K, H69Q, V77VI, L89MA
Vidal (2006)NV_KSS01302.KSS013AM041049None   L10M, I13V, K14R, G16A, K20I, E35D, M36I, R41K, R57K, H69K, K70R, L89MA
Baker (2007)P0185P0185-130605EF186145None   L10M, I13V, E35D, M36I, R41K, R57K, L63P, H69Q, L89MA
Ibe (2008)250250AB356272None   L10M, I13V, G16E, E35D, M36I, N37D, R41K, R57K, G68E, H69K, I72R, L89MA
Nyombi (2008)TMS011TMS011EU251791None   L10M, I13V, E35D, M36I, R41K, K45R, R57K, L63V, H69K, L89MA
Aghokeng (2009)CYV085CYV085GU191582None   L10M, I13V, G16E, K20R, E35D, M36I, R57K, L63T, H69K, L89MA
Avi (2009)U95U95FJ154011None   L10M, K14R, E35D, M36I, R41K, H69K, L89M, I93LA
Ayouba (2009)29132913HALDPRGQ351971None   I3L, L10M, V11M, I13V, K14R, K20I, M36I, R41K, H69K, L89MA
Steegen (2009)BV255BV255-1EU872130None   L10M, I13V, K14R, I15V, L19I, E35D, M36I, N37D, R41K, R57K, H69K, L89MA
Vercauteren (2009)pt13675024434105GQ399657None   L10M, I13V, G16E, E35D, M36I, N37D, L63S, E65D, H69K, K70KR, L89MA
Tovanabutra (2010)KECst_001KECst_001FJ623487None   L10M, I13V, E35D, M36I, N37D, R41K, K45R, R57K, E65D, H69K, L89MA
Towler (2010)337081-S337081-SHM037852None   L10M, I13V, K14R, M36I, R41K, L63V, H69K, L89MA
Charpentier (2011)232CP 001 1420 None   L10M, I13V, M36I, R41K, K43KR, H69K, L89IA
Ndembi (2011)AICPS035AICPS035HQ702682None   L10M, I13V, K14R, I15V, G16E, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
De Gascun (2012)IRL05422IRL05422JN622295None   L10M, I13V, K20R, E35D, M36I, P39Q, R41K, R57K, D60E, Q61E, I62V, C67Y, H69K, K70R, L89MA
Antoniadou (2013)GR134GR134KF671842None   L10M, I13V, K14N, E35D, M36I, R57K, L63T, H69K, K70KR, I72IT, V77I, L89MA
 GR140GR140KF671849None   L10M, I13V, K14N, E35D, M36I, R57K, L63T, H69K, V77I, L89MA
Hassan (2013)RS09000956RS09000956HQ441696None   L10M, I13V, E35D, M36I, N37D, R41K, R57K, D60E, Q61E, C67Y, H69K, K70R, L89MA
Pircher (2013)A1018A1018JX110267None  V11II3V, L10M, T12S, I13V, L19I, E21EK, M36I, R41K, H69K, L89IA
Sigaloff (2013)MBA047_0MBA047_0JX182018None   L10M, I13V, M36I, R41K, C67Y, H69K, L89MA
Lee (2014)MBA1151MBA1151KJ906849None   L10M, I13V, M36I, R41K, R57K, H69K, L89MA