<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L10F
Rx >= 1 PI
IncludeMixtures No
References 13
Patients 23
Isolates 25
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Montes (2004)MB_patMUZ00_MUZ714AJ577959NFV18 L10FI13V, E35D, M36I, R41K, R57K, H69K, L89IA
Non-B Workgroup (2005)TK1010TK1010b IDV, Unknown>229 L10FT12I, I13V, G16E, E35D, M36I, R41K, R57K, I62V, L63H, H69K, K70R, L89MA
 TK4006TK4006 NFV83N88SL10FI13V, I15V, K20I, E35N, M36I, R41K, K45R, R57Q, H69K, L89IA
 TK5002TK5002 NFV189N88SL10FI13V, K14R, I15V, K20T, E35D, M36I, R41K, K45R, R57K, H69K, L89IA
Weber (2005)M41971M41971AY677401IDV, NFV, LPV181I54V, V82AL10F, L33IT4TS, I13V, G16E, L19LI, K20R, E35D, M36I, N37D, R41K, K45V, K55T, R57K, L63H, H69K, K70R, L89M, T91TSA
 01M612201M6122AY677413NFV224N88SL10FI13V, K20I, E35D, M36I, R41K, H69K, L89MA
Baxter (2006)12-21202120-30715DQ876783PINAM46I, I47V, L90ML10F, L33I, F53L, G73GS, N88G, L89VI13V, K14R, K20T, E35D, M36I, R41K, R57K, I62V, L63P, H69K, A71IA
  2120-40510DQ876754PI, RTV, TPV>43M46I, I47V, L90ML10F, L33I, F53L, G73S, N88G, L89VI13V, K14R, K20T, E35D, M36I, R41K, R57K, I62V, L63P, H69K, A71IA
 48-32643264-30703DQ878168PINAM46I, I54V, I84V, L90ML10F, L89VI13V, K14KR, G16E, K20L, M36I, D60E, Q61H, L63R, I66V, H69K, K70R, A71T, P79A, I93L, C95FA
  3264-40322DQ878169PI, RTV, TPV>38M46I, I54V, I84V, L90ML10F, L89VI13V, G16E, K20L, L23M, M36I, D60E, Q61H, L63R, I66V, H69K, K70R, A71T, P79A, I93L, C95VA
 48-41534153-30326DQ878387PINAM46I, I54L, L76V, I84VL10FI13V, G16E, K20I, L33L_L, E35D, M36I, R57K, Q61R, L63T, H69K, L89I, T91TSA
 48-50325032-30421DQ878558PINAI54V, L90ML10F, L33I, L89VI13V, E35D, M36I, R41K, R57K, I62IV, L63LP, H69KA
Dau (2010)11741A11741AGU582052PINAN88SL10F, L89VI13V, K20T, E35D, M36I, R41K, I62V, L63P, H69K, T74SA
Charpentier (2011)CR-43CR-43FJ688249PINAM46I, V82FL10FI13V, K14R, I15V, K20I, E35D, M36I, N37D, R41K, L63T, H69K, T74TA, L89M, I93MA
 CR-13CR-13FJ688219PINAM46IL10F, L89VI13V, K20I, M36I, R41K, L63LP, H69K, I93MA
Barber (2012)4882648826JQ361679LPV V32I, M46I, I47AL10F, L33I, L89VI13V, K20R, E35D, M36I, R41K, R57K, I62V, H69K, K70R, T74SA
Jones (2012)160444160444JN669977PINAI54IVL10F, F53FLI13V, E35D, M36I, N37D, R41K, L63V, H69K, K70R, T74A, L89M, T91VA
 178278178278JN670478PINAI54V, V82VA, L90LML10F, F53LI13V, K20I, E35D, M36I, N37D, R41K, I62V, L63V, H69K, K70R, T74A, L89M, T91VA
Kouri (2012)CU544-09CU544-09JQ585255PINAM46I, I47V, I54V, I84V, L90ML10F, V11VI, L33I, Q58E, G73S, T74P, N88G, L89VI13AV, K14R, K20IT, E35N, M36I, N37D, R41K, I62V, L63V, H69K, K70RA
Kolomeets (2014)175175_272KJ870393PINAM46LL10FI13V, M36I, R41K, H69K, T74S, V77I, L89MA
Nerrienet (2014)U0407179U0407179JN675767LPV M46I, I84V, L90ML10F, L33F, F53L, Q58E, G73GS, N88G, L89VI13V, K20T, E35D, M36I, R41K, K55R, R57K, L63P, I66IF, H69K, A71VA
 R1113090R1113090JN675748LPV M46I, I47V, L76V, I84VL10FI13V, G16Q, L19V, K20I, E35D, M36I, P39S, R41K, K55R, D60E, I66F, H69K, A71AV, L89MA
Abdellaziz (2016)1505115051KT339029PINAV32I, M46I, V82AL10F, K43T, L89VI13V, K20M, M36I, L63P, H69K, A71VA
Ndahimana Jd Riedel (2016)21332133KT982485LPV M46I, I54V, V82A, I84VL10FI13V, G16E, K20R, E35D, M36I, N37E, R41K, K45I, R57K, Q61N, L63H, H69K, K70R, I72IT, L89MA
 21652165KT982498LPV M46I, I54V, V82AL10F, L33FI13V, E35D, M36I, N37D, P39Q, R41K, K45I, R57K, D60NS, Q61E, L63P, H69Q, L89I, T91SA