<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation L74V
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 2
Patients 5
Isolates 6
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patHEN02_HEN716AJ577914ABC, AZT, 3TC, DDI, D4TNoneL74V, M184VV106A, G190AK22N, L26F, V35P, T39A, E40D, K43R, V60I, N81T, A98S, K122E, D123S, I135T, E138A, I142V, S162A, K173T, Q174K, D177E, I178V, T200A, Q207E, R211S, F214LG
Non-B Workgroup (2005)PL3551458316AY9015443TC, D4T, DDINoneL74V, V75A, M184V V35T, K43R, V60I, K73Q, K122E, D123S, Q174E, D177E, T200A, Q207K, R211S, H221HY, V245Q, E248N, D250E, A272P, T286A, E291D, V292I, I293V, E297T, A304E, D320E, D324EG
 PL3515957564AY901677AZT, 3TC, DDI, ABC, D4TNoneM41L, L74V, M184V, T215Y V35T, V60I, A98S, K122E, D123S, I135V, K173IT, Q174K, D177E, T200A, Q207K, R211NS, V245Q, E248D, D250E, A272P, K281R, T286A, E291D, I293V, D324EG
 PL1481477297 AZT, DDI, 3TC, D4TNoneM41L, L74V, M184V, L210W, T215Y K20R, K32I, V35T, T39K, K43E, K49R, V118I, K122E, D123NS, I135V, E169A, K173A, Q174K, D177E, I178M, T200A, E203D, Q207E, H208Y, R211K, V245Q, E248D, A272P, E291D, V292I, I293V, E297A, D324E, I329VG
  78800 AZT, DDI, 3TC, D4TNoneM41L, L74V, M184V, L210W, T215Y K20R, K32I, V35A, T39K, K43E, K49R, V118I, K122E, D123N, I135V, E169A, K173A, Q174K, D177E, I178M, T200A, E203D, Q207E, H208Y, R211K, V245Q, E248D, A272P, E291D, V292I, I293V, E297AG
 PL2909097083 AZT, DDI, 3TC, D4TNoneM41L, D67N, L74V, M184V, L210W, T215Y V21I, V35T, T39A, K43Q, V60I, V118I, K122E, D123N, I135T, K173I, Q174K, D177E, I178M, T200A, Q207E, R211K, I244IV, V245K, D250E, A272P, T286A, E291D, V292I, I293V, E297A, A304E, D324E, I329VG

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