<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation K70R
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 3
Patients 23
Isolates 24
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patVERD00_VERD709AJ578173AZT, DDI, 3TC, D4TNoneM41L, D67N, K70R, M184V, T215Y, K219Q V35T, T39N, E40D, V60I, K122E, I135V, K173T, Q174R, D177E, I178L, T200A, I202V, Q207E, R211KG
Non-B Workgroup (2005)PL3379057583AY901539D4T, 3TCNoneK70R, M184V V35T, K43R, K49KR, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, E194Q, T200A, R211S, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297A, L301M, D320E, D324EG
 PL2750057633AY901540DDC, AZT, 3TC, D4TNoneD67N, K70R, M184V, K219E K20KR, V35T, V60I, A98S, V118VG, D123V, I135V, S162AD, K173I, Q174K, D177E, T200A, Q207EK, R211S, F214L, V245Q, E248A, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297A, D324EG
 PL848759877AY901565DDC, AZT, 3TCNoneD67N, K70R, M184V, K219E V35T, K43R, V60I, T69N, A98S, K122E, D123S, Y127CS, T128A, F130Y, I135X, K173R, Q174K, D177E, T200A, Q207K, R211S, F214L, V245Q, E248D, D250E, A272P, K277KR, T286A, E291D, V292I, I293V, E297AG
 PL3820264223AY901598AZT, DDINoneM41ML, D67N, K70R, T215Y, K219Q V35T, K43R, V60I, A98S, K122E, D123S, K173L, Q174K, D177E, I178M, T200A, Q207K, R211S, D218E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329VG
 PL3820164222AY901599AZT, DDI, D4T, 3TCNoneM41L, D67N, K70R, M184V, T215Y, K219E V35T, K43R, V60I, S68G, A98S, K122E, D123S, I135T, K173T, Q174K, D177G, T200A, Q207K, R211S, L228H, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L301M, D320E, D324E, I329VG
 PL2397263353AY901601D4T, 3TCNoneD67N, K70R, M184V K11KR, E28A, V35T, V60VI, K122E, D123S, I135T, S162C, K173T, Q174K, D177E, T200A, Q207K, R211S, F214FL, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
 PL3814564117AY901611DDC, AZT, 3TC, D4TNoneD67N, K70R, M184V, K219Q V35T, K49R, V60I, A98S, K122E, D123S, K173I, Q174K, D177E, I178L, E203K, Q207E, R211K, V245T, D250E, A272P, Q278N, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
 PL1003066215AY901629AZT, DDI, D4T, 3TCNoneM41L, D67N, K70R, M184V, T215Y, K219E V35T, K43R, V60I, A98S, K122E, D123S, I135T, K173R, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, E297A, D324E, I329VG
 PL4043369148AY901674DDC, AZT, 3TC, D4T, DDINoneM41L, D67N, K70R, V75M, T215Y, K219EK103N, G190AI2IV, V35T, K43R, E44ED, V60I, A98S, S117A, K122E, D123S, T139M, K173I, Q174K, D177E, T200A, E203ED, Q207K, R211S, L228H, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329VG
 PL3414765713AY901703AZT, DDINoneM41L, K70R, T215Y V35T, V60I, D67X, A98S, K122E, D123S, S162C, Q174E, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L310LM, I329VG
 PL1003066215 AZT, DDI, 3TC, D4TNoneM41L, D67N, K70R, M184V, T215Y, K219E V35T, K43R, V60I, A98S, K122E, D123S, I135T, K173R, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, E297A, D324E, I329VG
 PL2750672107 AZT, 3TCNoneM41L, K70R, M184V, T215Y V21VI, V35K, T39M, K43R, V60I, T69N, A98S, K122E, D123S, I135T, K173T, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297T, D320E, D324E, I329V, Q334LG
 PL32676102203 AZT, DDINoneM41L, D67N, K70R, T215FY, K219Q V35T, E40ED, K43R, V60I, A98S, K122E, D123N, I135L, S162F, K173L, Q174K, E194D, T200A, Q207G, R211S, L228H, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, E297T, A304E, D324E, I329VG
 PL3765463093 AZT, DDINoneM41L, D67N, K70R, T215F, K219E V35T, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297AG
 PL40388105421 3TC, D4TNoneD67N, K70R, M184V, K219Q V35T, K43KR, V60I, A98S, K122E, D123S, I135IT, K173R, Q174K, D177E, I195KT, T200A, R211NS, D218DE, V245Q, E248D, D250E, A272P, K275Q, V276T, K277R, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
 PL4236173571 D4T, DDI, AZT, 3TCNoneM41L, D67N, K70R, V75M, F77FL, M184V, T215Y, K219E V35T, K43R, K49R, V60I, K82KR, A98S, K122E, D123S, I135T, F171L, K173I, Q174K, D177E, T200A, E203D, Q207K, R211S, F214Y, D218DY, L228H, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297AG
 PL4315675500 AZT, DDI, 3TC, D4TNoneM41L, D67N, K70R, M184V, T215Y, K219E V35T, E40D, K43R, V60I, S68G, K104KR, D121DH, K122E, D123S, K173IM, Q174K, D177E, T200A, Q207K, R211ST, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
 PL4489979693 AZT, 3TCNoneD67N, K70R, M184V V35T, V60I, A98S, K122E, D123S, I135V, K166R, K173A, Q174K, D177E, I178M, T200A, E203K, Q207E, R211S, K219G, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, N306T, D324E, I329V, K331NG
 PL5119596176 ABC, AZT, 3TCNoneD67N, K70R, M184V V35T, E36ED, K49R, V60I, A98S, K101Q, K102R, K122E, D123S, K173R, Q174K, T200A, Q207K, R211S, V245Q, E248D, D250E, S251N, A272P, T286A, E291D, V292I, I293V, E297T, K311KR, P321S, D324E, I329VG
 PL86570861 DDC, AZT, 3TC, D4TNoneD67N, K70R, M184V, K219Q V35T, K43R, V60I, T69TN, K122E, D123S, I135T, K173R, Q174K, D177E, T200A, Q207K, R211S, F214FL, V245Q, E248D, D250E, A272P, R284RK, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
 PL1197773201 3TC, D4T, AZTNoneM41L, D67G, K70R, M184V, K219Q L34I, V35T, T39A, V60I, T69N, A98S, V111I, K122E, D123S, I135V, S162Y, Q174E, D177E, T200A, Q207K, R211S, F214L, V245Q, E248D, D250E, A272P, K277RG
 PL4322PL4322 ABC, AZT, 3TCNoneD67N, K70R, M184V, T215F, K219Q V35T, N54I, V60I, T69TN, A98S, K122E, D123S, I135L, I167IV, K173A, Q174K, D177E, T200A, Q207QK, R211N, D218E, V245Q, E248D, D250E, A272P, T286A, A288AT, E291D, V292I, I293V, E297A, D324E, I329V, K331NG
Knops (2010)Pat12Pat12GU991873AZT, 3TCNoneD67N, K70R, M184V, K219Q V35T, V60I, R83RK, K104R, K122E, D123S, K173R, Q174R, D177E, I178M, T200A, Q207E, R211K, F214L, K238R, V245Q, E248D, D250E, A272P, V276I, K277R, L283I, T286A, V292I, I293V, E297A, V317A, D324E, I329VG