<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation S68G
Rx RTI-naive
IncludeMixtures No
References 18
Patients 36
Isolates 36
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Njouom (2003)23rev23revAY204334NoneNone  V35T, E36D, S68G, V90I, D123E, I135V, S162A, T165I, K173A, Q174K, D177E, T200A, Q207E, L234X, K238GG
 01rev01revAY204349NoneNone  V35T, T39M, V60VI, S68G, V90I, S162A, K173T, Q174K, D177E, I178M, T200A, Q207G, R211K, V245EG
Toni (2003)TTDDP50TTDDP50AY207939NoneNone  K30E, V35T, T39R, V60I, S68G, D123E, I135V, S162A, F171Y, K173A, Q174K, P176PS, D177E, T200A, Q207EG
Lawrence (2006)04TE0404TE04DQ251592NoneNone  T39A, E40D, K49KR, S68G, K104R, I135R, S162A, K173I, Q174K, D177E, T200A, Q207E, R211RG, F214L, V245QG
Marechal (2006)JF_129JF_129DQ443614NoneNone  V35T, T39K, V60I, S68G, K122KPQT, D123N, I142V, A158S, K173A, Q174K, D177E, T200A, Q207K, H208HL, R211T, V245EG
Cuevas (2009)X2558_1X2558_1GU326136NoneNone  K20R, V35I, S68G, A98S, K122E, D123S, I135T, T139S, Y144F, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, K277R, V292I, I293V, E297RG
Brennan (2010)ARC-A127ARC-A127GU565659NoneNone  K11R, V35K, V60I, S68G, K104KR, K122E, D123N, I135T, S162SN, K173T, Q174R, D177E, T200A, Q207E, R211K, V245Q, E248S, D250E, A272P, K281R, T286A, E291D, I293V, P294A, S322T, I326VG
Castro (2010)PHI-24PHI-24GQ131619NoneNone  T27S, V35T, T39A, V60I, S68G, K104R, K122E, D123N, I135T, K173T, Q174R, D177E, I178M, V189I, I195T, T200A, Q207D, R211K, V245Q, E248D, D250EG
Soares (2010)CM05_103CM05_103GU366156NoneNone  V35T, T39A, K43R, S68G, T69S, I135R, S162A, K173T, Q174N, D177E, T200A, Q207E, R211K, V245EG
Charpentier (2011)patng_08patng_08HQ021238NoneNone  V35T, E36AD, E40ED, V60I, S68G, V90VI, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, V245QG
 patng_32patng_32HQ021261NoneNone  V35T, V60I, S68G, I135V, S162A, E169A, K173AT, Q174E, D177E, I178M, T200A, E203D, Q207K, R211K, V245Q, E248NG
 patng_34patng_34HQ021263NoneNone  V35T, V60I, S68G, T69TA, K122E, D123NS, K173R, Q174K, D177E, I178M, G196E, T200A, Q207E, R211K, P243SG
 patco_17patco_17HQ021330NoneNone  V35T, V60I, S68G, I135V, E138A, S162A, T165TI, K173T, Q174K, D177E, T200A, Q207E, R211KG
 patco_03patco_03HQ021331NoneNone  V35VAIT, E36D, T39TAIV, K49R, V60I, S68G, K122KE, D123DN, I135IT, S162A, K173T, Q174K, D177E, I178M, T200A, I202IV, Q207X, R211K, F214FLG
 patco_97patco_97HQ021365NoneNone  V35T, K49R, V60I, S68G, I135V, I159V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207EG
 patco_53patco_53HQ021370NoneNone  V35K, V60I, K66N, S68G, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207DEG
Hamers (2011)CP076303498CP076303498HQ993986NoneNone  K20R, V35T, T39K, E40D, V60I, S68G, K122E, D123N, I135T, T165I, K173T, Q174S, D177E, T200A, Q207E, V245T, D250E, S251H, A272S, K275KQ, K277R, Q278S, T286A, E291D, V292I, I293V, E297A, L301MG
 CP076303569CP076303569HQ994041NoneNone V179EV35T, K49R, V60I, S68G, D123E, I135T, T165I, K173T, Q174K, D177E, I178IM, I195T, T200A, Q207G, R211K, P243PST, V245Q, E248DN, D250E, A272P, T286A, V292I, I293V, V317A, I329VG
 CP076303597CP076303597HQ994061NoneNone  V35T, T39A, E40ED, V60I, S68G, D123DEKN, I135R, K173I, Q174K, D177E, T200A, Q207E, R211RK, V245Q, E248EDKN, D250DE, S251SN, A272P, T286A, A288AS, E291D, V292VI, I293V, P321S, D324E, I329VG
 CP076303617CP076303617HQ994077NoneNone  V35T, T39TS, K43R, V60I, S68G, K104KR, K122E, D123NS, I135T, K173IM, Q174K, D177E, I178M, T200A, Q207E, R211RK, V245Q, E248D, D250E, A272P, V276VI, T286A, E291D, V292I, I293V, P294T, D324E, I329VG
Frange (2012)370215AOL370215AOLJQ292237NoneNone  K49R, S68G, I135V, S162A, K173T, Q174K, D177E, T200A, Q207N, R211E, P243A, V245Q, D250EG
 920603JSB920603JSBJQ292266NoneNone  S68G, K122E, D123E, I135V, E138A, R143RK, S162A, K173T, Q174E, D177EG
 920214GSX920214GSXJQ292353NoneNone  V35T, T39R, K43E, V60I, S68G, I135V, S162A, K173T, Q174K, D177E, T200A, Q207EG
 750741DWD750741DWDJQ292380NoneNone  V60I, S68G, K122E, D123N, I135K, S162C, K173R, Q174K, D177E, I178M, Q207E, R211K, V245Q, E248DG
 540108GYT540108GYTJQ292383NoneNone  V60I, S68G, K102Q, K122E, D123S, I135K, K173T, Q174K, I178L, I195L, T200A, R211K, P243AG
 750907OTT750907OTTJQ292390NoneNone  T27P, V35T, V60I, S68G, K102Q, D123S, K166R, K173T, Q174R, D177E, I178L, T200A, Q207N, R211E, V245Q, E248D, D250EG
Bartolo (2014)09AOHDP3709AOHDP37KF853717NoneNone  K11AT, V21VI, T27S, V35T, T39K, E40D, K43Q, V60I, S68G, K122E, D123G, I135V, S162A, K173R, Q174K, D177E, T200A, Q207K, R211S, V245Q, D250E, S251D, A272P, I274IV, K275Q, K277R, Q278HN, K281R, T286A, E291D, V292I, I293V, E297AG
Meixenberger (2014)09-0284609-02846KJ771075NoneNone  K32R, V35T, V60I, S68G, K122E, I135V, S162A, Q174R, D177E, I178M, D192N, T200A, E204D, Q207G, R211K, V245Q, E248N, D250E, A272P, V276T, K277R, T286A, E291DG
Alexiev (2015)907_1108907_1108JQ259157NoneNone  T39A, S68G, D121H, K122E, I135T, G141GR, S162A, K173T, Q174K, D177E, T200A, Q207G, V245QG
 908_1208908_1208JQ259158NoneNone  T39A, S68G, D121H, K122E, I135T, S162A, K173T, Q174K, D177E, T200A, Q207D, V245QG
Carvalho (2015)3838KM206040NoneNone  V60I, S68G, A98S, K122E, D123S, I135L, Q151QE, S162G, K173R, Q174K, D177E, I195K, G196E, T200A, E203Q, R211RK, V245QG
Dauwe (2015)iAG_11004RiAG_11004RKT864308NoneNone  V60I, S68G, K122E, S162A, Q174R, D177E, T200A, E204D, Q207G, R211KG
 NA_05_64NA_05_64KT864329NoneNone  T39A, S68G, K122E, I135T, K173A, Q174K, D177E, I178M, I195L, T200A, R211KTG
Diallo (2015)1-1-1371-1-137JX084075NoneNone  V35T, V60I, S68G, K166R, F171Y, K173A, Q174K, D177E, I178M, T200V, Q207D, R211K, P243T, V245QG
 2-1-0352-1-035JX084155NoneNone  E6D, V35T, V60I, S68G, K104R, K173T, Q174K, D177E, I178M, T200A, Q207E, V245Q, E248NG
Onywera (2017)15313021531302KX790983NoneNone V179EP4S, V35T, T39S, V60I, S68G, D123E, A158S, Q174E, D177E, I178M, I195L, T200A, Q207E, R211K, V245Q, D250EG