<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation E40D
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 4
Patients 11
Isolates 12
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patHEN01_HEN734AJ577913ABC, AZT, 3TC, DDINoneM184I V35T, T39A, E40D, K43R, V60I, A98S, K122E, D123S, I135T, E138A, I142V, S162A, K173T, Q174K, D177E, I178V, T200A, Q207E, R211S, F214LG
  02_HEN716AJ577914ABC, AZT, 3TC, DDI, D4TNoneL74V, M184VV106A, G190AK22N, L26F, V35P, T39A, E40D, K43R, V60I, N81T, A98S, K122E, D123S, I135T, E138A, I142V, S162A, K173T, Q174K, D177E, I178V, T200A, Q207E, R211S, F214LG
 MB_patVERD00_VERD709AJ578173AZT, DDI, 3TC, D4TNoneM41L, D67N, K70R, M184V, T215Y, K219Q V35T, T39N, E40D, V60I, K122E, I135V, K173T, Q174R, D177E, I178L, T200A, I202V, Q207E, R211KG
Delaugerre (2005)Pt1Pt1AY311593ABC, AZT, 3TC, DDI, TDFNoneK65R, K70E, M184V K20R, V35T, T39K, E40D, V60I, K122E, D123S, P157S, K166R, K173T, Q174K, D177E, I178M, T200A, Q207A, R211K, V245Q, E248D, D250EG
Non-B Workgroup (2005)PL3607159529 AZT, 3TCNoneM184V V35T, E40D, K49R, V60I, V90I, A98S, S162N, K173IT, Q174K, D177E, G196E, Q207E, V245T, D250E, A272P, V276VI, Q278N, T286A, E291D, V292I, I293V, P294T, E297D, R307K, D320E, D324E, I329VG
 PL3655160625AY901560AZT, 3TCNoneM184V V21I, V35T, E40D, K43R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, F214L, V245Q, E248N, D250E, A272P, K277R, T286A, I293V, E297A, D320E, D324EG
 PL3349961173AY901563DDC, AZT, 3TC, DDI, D4TNone  V35T, E40D, K43R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, Y319Y*G
 PL3713261949AY901574AZT, 3TCNoneD67DN, K70KR, M184V, K219KQ V35T, E40D, K43R, V60I, A98S, K122E, D123S, I135X, E138A, K173IT, Q174K, T200E, Q207K, R211S, F214FL, V245Q, E248D, D250E, A272P, T286A, E291D, V292VI, N306XG
 PL3679561171AY901577AZT, 3TCNone  V35T, E40D, K43R, V60I, A98S, K122E, D123S, I135T, K173R, Q174K, D177E, T200AV, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320EG
 PL4315675500 AZT, DDI, 3TC, D4TNoneM41L, D67N, K70R, M184V, T215Y, K219E V35T, E40D, K43R, V60I, S68G, K104KR, D121DH, K122E, D123S, K173IM, Q174K, D177E, T200A, Q207K, R211ST, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, E297A, D324E, I329VG
 PL4512280255 ABC, AZT, 3TCNoneV75I, F77L, F116Y, Q151M, M184V V21I, V35T, E40D, V60I, A98S, K122E, D123S, S163T, K173T, Q174K, D177E, T200A, R211S, V245Q, E248A, D250E, A272P, Q278H, T286A, E291D, V292I, I293IV, E297A, A304E, I329V, K331NG
Inzaule (2013)519519JQ914088AZT, 3TCNone  V21I, V35T, E40D, K43R, V60I, K122E, Q174K, D177E, I178M, T200A, Q207K, R211NG