<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype G
Gene RT
Mutation V118I
Rx RTI-naive
IncludeMixtures No
References 16
Patients 25
Isolates 25
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Gao (1998)92NG00392NG003U88825NoneNone  M16I, V35T, E40D, V60I, K104R, V118I, K122E, D123N, K173T, Q174E, D177E, I195T, T200A, Q207N, V245Q, E248N, D250E, A272P, T286A, E291D, V292I, I293V, D324E, I329L, Q334C, G335D, F346Y, R356K, M357R, R358G, G359S, T386V, Q394R, A400V, E413D, Q428R, K431T, V435P, F440Y, R448K, R463K, V466I, V467I, S468T, L469I, T470Q, D471E, Q480H, H483Q, L491S, K512R, S519N, A534T, A554SG
Vergne (2002)LVLBV26_05LVLBV26_05AJ313401NoneNone A98GK20R, V35T, T39E, E40D, V60I, K104R, V106I, V118I, D123S, I135V, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, E248D, D250E, S251I, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, P294T, E297T, L301M, P321Q, D324E, I329V, Q334L, G335D, F346Y, R356K, M357K, R358G, G359S, A371V, S379G, T386V, K390R, Q394R, A400VG
Paraskevis (2005)GRSPR58GRSPR58AY940307NoneNone  V60I, V118I, K122V, D123DN, K173T, Q174K, D177E, I178V, T200A, Q207E, F214L, V245QG
 GRSPR22GRSPR22AY940306NoneNone  V60I, V90G, V118I, K122V, K173T, Q174K, D177E, I178M, Q207E, R211RK, P217Q, K238XG
Yamaguchi (2009)944-5944-5FJ389366NoneNone  E6D, V35T, T39K, E40D, V60I, K104KR, V118I, D121Y, K122E, T165I, F171Y, K173E, Q174R, D177E, D192DN, T200A, Q207E, R211K, F214L, V245Q, E248D, D250E, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, T296TS, E297A, L301M, D324E, I329V, Q334L, G335D, Y339YD, F346Y, R356K, M357R, R358G, G359S, V365I, A371V, T386I, Q394R, A400V, K431T, V435L, F440Y, R461RK, R463K, V466I, V467I, S468A, D471E, T477A, Q480H, H483Q, L491S, K512R, S519N, V531I, A534S, A554S, V559IG
Yebra (2009)SP132-287163SP132-287163EU255477NoneNone  V35T, V60I, W88X, K104KR, V118I, K122E, D123S, T165I, K173T, Q174K, D177E, G196GE, T200A, Q207E, F214L, V245Q, E248D, D250E, A272P, L279I, T286A, E291D, V292I, I293V, K311KR, D324E, I329VG
Bonura (2010)1238_1341238_134GU969569NoneNone  K20R, V35T, E40D, V60I, K104R, V118I, K122E, D123S, I135R, T165I, K173IT, Q174K, D177E, I178IM, I195T, G196E, T200A, Q207E, F214L, L228Q, V245HQ, E248D, D250E, A272P, T286A, E291D, V292I, I293V, P294A, I329VG
 1239_1351239_135GU969570NoneNone  K20R, V35T, E40D, V60I, K104R, V118I, K122E, D123NS, I135IR, T165I, K173T, Q174K, D177E, I195T, G196E, T200A, R206RK, Q207E, F214L, L228Q, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, P294A, I329VG
Charpentier (2011)patng_14patng_14HQ021244NoneNone  K20R, V35T, T39Q, V60I, R78RK, V118I, K122E, D123DN, I135T, T139TAS, I142IT, Q174DGNS, D177E, I178M, T200A, Q207E, F214L, L228Q, V245Q, E248N, D250EG
 patng_82patng_82HQ021310NoneNone  E28D, V35T, V60I, K104R, V118I, K122E, D123N, I135R, K173I, Q174K, D177E, T200A, Q207E, F214L, V245K, D250EG
Hamers (2011)CP076303513CP076303513HQ993996NoneNone  P4S, K20R, V35T, T39E, E40D, V60I, V118I, K173T, Q174K, D177E, I178L, T200A, Q207E, R211RK, F214L, V245Q, E248D, S251T, A272P, T286A, E291D, V292I, I293IV, E297AP, L301M, S322AG
 CP076305212CP076305212HQ994146NoneNone  V35T, I47S, S48T, V60I, V106I, V118I, K122E, D123DN, I135R, K173T, Q174K, D177DE, I178L, T200A, I202V, Q207E, F214L, V245M, E248EDKN, D250DE, A272P, T286A, E291D, V292I, I293V, I329VG
Caron (2012)Gab051004Gab051004HQ541916NoneNone  V21I, V35T, T39K, E40D, V60I, V118I, D121H, K122E, I142V, S162N, K173T, Q174A, D177E, I178M, T200A, Q207E, R211K, V245Q, E248D, D250EG
De Gascun (2012)IRL38692IRL38692JN622330NoneNone  V60I, K64KR, V118I, K122E, I142T, K173AT, Q174K, D177E, T200A, Q207DN, R211K, F214LG
Frange (2012)440153MQ440153MQJQ292399NoneNone  T39K, V60I, V118I, S162A, T165I, K173T, Q174R, D177E, I178L, T200A, Q207E, R211K, F214LG
Frentz (2013)EHR-13657EHR-13657JX299764NoneNone  K32I, V35T, T39K, V60I, K64KR, V118I, K122P, E138A, I142V, T165TI, K173A, D177E, T200A, I202V, E204D, Q207K, R211K, F214L, V245QG
Telan (2013)1106382211063822AB747478NoneNone  E6D, K20R, V35T, T39E, E40D, V60I, V118I, K122E, I135T, K173A, Q174K, D177E, I178M, I195L, T200A, Q207E, L210M, R211K, F214L, V245Q, E248D, D250E, S251N, A272P, Q278H, L279IG
Dauwe (2015)AG_06_01AG_06_01KT864121NoneNone  T39A, E40D, V118I, D123E, I135V, T165I, K173A, Q174K, D177E, T200A, Q207E, F214LG
Diallo (2015)2-1-0462-1-046JX084163NoneNone  K20R, V35T, T39K, E40D, V60I, F87FL, V118I, I159V, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, K238R, V245Q, E248DG
 1-1-1571-1-157JX084094NoneNone  P4PS, V35T, T39L, V60I, K64KR, V118I, K122KEIV, E138A, K173T, Q174K, T200A, I202V, Q207E, R211K, F214L, P243PS, V245Q, E248DG
 2-1-0362-1-036JX084156NoneNone  V35T, K43R, V60I, K104KR, V118I, K122E, D123S, S162SDGN, T165TI, F171FY, K173T, Q174K, D177E, I178M, T200A, Q207E, F214L, V245Q, E248DG
 1-1-0921-1-092JX084032NoneNone  V35T, V60I, V118I, K122AV, D123NS, K173T, Q174K, D177E, I178L, T200A, Q207E, R211RK, F214L, P243S, V245Q, E248DG
Heipertz (2016)NG060248NG060248KX389646NoneNone  V35T, T39A, E40D, V60I, V118I, D123S, I135T, K173T, Q174K, D177E, G196E, T200A, I202V, Q207D, R211K, F214L, T240M, V245Q, E248D, D250E, S251N, A272P, T286A, E291D, V292I, I293V, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, V381I, T386V, Q394K, A400V, E413D, K431T, V435L, F440Y, L452I, R461K, R463K, V466I, V467I, S468T, L469I, T470Q, D471E, Q480H, H483Q, L491S, S519N, A534T, A554SG
 NG010261NG010261KX389626NoneNone  K20R, V35T, E40D, V60I, V118I, K122Q, D123S, I135V, S163T, K173I, Q174K, D177E, T200A, Q207E, F214L, V245Q, A272S, K277R, T286A, K287KE, E291D, V292I, I293V, E297T, Q334S, G335D, F346Y, R356K, M357R, R358G, G359S, K366R, I375V, T386V, K390R, Q394R, A400V, E413D, Q428R, K431T, V435L, F440Y, E449D, R463K, V466I, V467I, S468T, L469I, T470Q, D471E, T477A, E478EK, Q480H, H483Q, L491A, K512R, S519N, K527N, A534T, A554SG
 NG020133NG020133KX389620NoneNone  P4T, E6K, K20R, V35T, V118I, K122E, D123N, T165I, K173A, Q174K, D177E, T200A, Q207E, F214L, V245Q, E248N, D250E, S251N, A272P, T286A, E291D, V292I, I293V, I329V, Q334L, G335D, F346Y, R356K, M357R, R358E, G359S, K366R, A371V, T377K, I382T, T386V, Q394R, A400V, Q428R, K431T, V435P, E438D, F440Y, V458I, R461K, R463K, V467I, S468T, L469I, T470Q, D471E, H483Q, L491S, L503I, S519N, A534T, A554SG