<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype F
Gene RT
Mutation K70R
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 9
Patients 19
Isolates 20
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Balotta (2000)CB-231CB-231AF252092DDC, AZT, 3TCNoneK70R, M184V, K219Q V35T, E40D, T69N, D123E, I135L, S162W, K166R, K173A, Q174K, V179I, T200A, Q207G, R211K, V245QF
Brindeiro (2002)TVSP16TVSP16AY145813AZT, 3TC, D4TNoneD67N, K70R, M184V, K219Q V35K, K102R, D123E, I135L, S162W, E169D, K173A, Q174K, D177E, I178V, S191T, T200A, E203K, Q207E, R211K, F214L, V245Q, A272P, T286P, E291D, V292I, I293V, E297TF
Apetrei (2003)AC_Pat21RO.00.IS.21AY333610AZT, 3TCNoneK70R V35T, T39A, E40D, K49R, D123E, I135L, S162Y, E169A, K173A, Q174K, I178M, I195L, Q207E, R211KF
  RO.01.IS.21AY333611AZT, 3TCNoneK70R V35T, T39A, E40D, K49R, E53G, D123E, I135L, S162Y, E169A, K173T, Q174K, I195L, Q207E, R211KF
 AC_Pat45RO.00.IS.45AY333585AZT, 3TCNoneK70R, M184V V35T, T39A, E40D, E53G, D123E, I135L, S162H, K166R, K173A, Q174R, I195L, T200A, Q207A, R211KF
 AC_Pat47RO.00.IS.47AY333586AZT, 3TCNoneK70R V35T, T39A, K102Q, D123E, I135L, S162H, K173A, Q174R, D177N, I195L, T200A, Q207A, R211KF
Soares (2003)BR60BR60AY275750D4T, DDINoneD67N, K70R, T215Y, K219QA98GV35T, T39L, V60I, I135T, I142V, S162Y, K173T, Q174K, T200A, Q207E, F214LF
Machado (2004)CS257CS257AY569970AZT, DDI, 3TCNoneD67N, K70R, M184V D121A, K122E, I135V, S162C, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, F214LF
Machado (2004)cs121cs121AY313411AZT, DDINoneM41L, D67N, T69D, K70R, T215F K49R, K122E, S162C, K173T, Q174K, D177E, I178L, Q207E, R211KF
 cs126cs126AY313376AZT, DDI, 3TCNoneD67N, K70R, M184V E40D, K49R, I135V, S162C, E169D, K173A, Q174K, I178L, T200A, E203K, Q207E, R211AF
 cs128cs128AY313378AZT, DDI, 3TCNoneD67N, T69D, K70R, M184V, T215F, K219Q K49R, I135V, S162C, E169D, K173A, Q174K, I178L, T200A, R211AF
 cs138cs138AY313417AZT, DDINoneM41L, D67N, K70R, T215Y, K219E T39K, V60I, K102Q, D123E, S162C, E169D, K173A, Q174K, Q207E, R211K, K220NF
 cs139cs139AY313418AZT, DDI, 3TCNoneD67N, K70R, M184V, T215V T39M, I47F, V60I, T69A, V90I, K122E, I135L, S162H, K173T, Q174K, G196E, R211KF
Non-B Workgroup (2005)BR37BR37AY901429AZT, DDINoneD67N, K70R, T215F K49R, I135V, S162C, E169D, K173A, Q174K, T200A, Q207E, R211KF
 PL4051769351 AZT, 3TC, D4T, DDINoneM41L, D67N, K70R, T215F, K219Q V35T, V60I, D123E, S162C, E169D, K173A, Q174K, I178L, E203D, Q207E, R211K, D218E, K223Q, L228H, V245Q, E248D, A272P, E291D, V292I, I293V, P294T, E297T, S322T, I329LF
Rodrigues (2005)BR01380397AY643263AZT, DDINoneM41L, D67N, K70R, T215Y, K219Q E28D, V35I, T39A, I135L, S162C, E169D, K173A, Q174K, I178L, T200A, Q207E, H208Y, R211KF
 BLF_Pat16BR03SP111AY643232AZT, DDI, 3TCNoneM41L, D67N, K70R, M184V, T215Y, K219E V35MT, K43E, E44A, T107S, L109I, D123E, S162C, K173A, Q174K, D177E, T200A, E203D, Q207D, H208Y, R211K, W212L, H221Y, L228H, V245Q, E248D, S251D, A272P, T286A, E291D, V292I, I293V, E297T, V317A, Q334CF
Dumans (2009)RENA140RENA140FJ405170AZT, 3TCNoneD67N, K70R, M184V, T215FY, K219E E28K, V35T, K122Q, I135V, S162C, E169D, K173T, Q174K, I178L, T200A, I202V, Q207A, R211Q, V245Q, E248D, A272P, T286A, A288T, E291D, V292I, I293V, E297A, I329LF
 RENA390RENA390FJ405175AZT, DDI, 3TCNoneK70R, M184V V35T, T39N, K122E, D123E, S162C, E169D, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, E297AF
 RENA332RENA332FJ405177AZT, 3TC, D4T, DDINoneD67N, K70R, M184V, K219EQV179D, Y181CK20R, V90I, K102Q, K103R, D123E, I135V, S162C, E169D, K173A, Q174K, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, A288T, E291D, V292I, I293V, E297A, V317AF