<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype F
Gene RT
Mutation S68G
Rx RTI-naive
IncludeMixtures No
References 8
Patients 31
Isolates 31
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Paraschiv (2007)23012301_2004JQ082994NoneNone V179DV35T, T39A, E40D, S68G, D123E, I135L, I142IT, S162H, K173I, Q174K, D177E, I195L, G196E, T200A, E203D, Q207T, R211K, V245Q, E248N, A272P, K277KR, T286A, E291D, V292I, I293V, P294T, E297A, I326MF
Diop-Ndiaye (2010)923hald923haldFN599757NoneNone  E28K, K32E, V35T, T39KR, S68G, K122E, S162SN, K173A, Q174K, D177E, T200A, Q207E, V245Q, A272P, Q278QH, T286A, E291D, V292I, I293V, E297A, E308EQ, D324E, R356K, G359S, T377M, S379C, K390KQ, P392PS, I393IM, K395R, T403IF
Florea (2011)1635_20071635_2007JQ083029NoneNone  V35I, S68G, D123E, I135T, S162C, K173V, Q174K, I178L, I195L, T200A, Q207A, R211EK, V245Q, E248DN, A272P, K277V, T286A, E291D, V292I, I293V, E297A, A327AVF
 4635_20084635_2008JQ083060NoneNone  V35T, V60I, S68G, K101R, D123E, I135T, I142V, S162H, S163I, K166KPQT, K173V, Q174K, D177E, E194D, I195L, G196E, T200A, Q207A, V245Q, E248N, A272P, K277R, T286A, E291D, V292I, I293V, L295P, E297T, A304EF
 4644_20074644_2007JQ083066NoneNone  V35T, V60I, S68G, D123E, I135T, I142V, S162H, K173V, Q174K, D177E, E194D, I195L, G196E, T200A, Q207A, V245Q, E248N, A272P, T286A, E291D, V292I, I293V, E297T, A304EF
Santos (2011)J202J202_PR_RT_CN_RHJN010611NoneNone  V35VA, T39A, K49R, V60I, S68G, K104KR, D123E, I135T, K173KT, Q174QK, T200A, Q207R, R211K, V245Q, L246V, A272P, K277R, K281R, T286A, E291D, V292I, I293V, E297A, I329V, K374T, T377R, K390R, E399D, A400T, K431T, V435A, A446S, L452K, R461K, V466A, D471E, T477A, Q480Y, L491S, E492K, S519N, K527N, L533M, A534S, V559IF
 J349J349_PR_RTJN010732NoneNone  K20R, V21I, V35T, T39M, S68G, D123E, S162C, E169D, K173A, Q174K, T200I, Q207A, R211K, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, E297TF
Frentz (2013)EHR-12976EHR-12976JX299747NoneNone  V35T, V60I, S68G, D123E, I135T, I142V, S162H, K173V, Q174K, D177E, E194D, I195L, G196E, T200A, Q207A, V245QF
 EHR-88776EHR-88776JX301048NoneNone  V35T, V60I, S68G, K101R, D123E, I135T, I142V, S162H, S163I, K166KPQT, K173V, Q174K, D177E, E194D, I195L, G196E, T200A, Q207A, V245QF
Bartolo (2014)09AOHDP25909AOHDP259KF853688NoneNone V179VFP4T, I5V, V35T, V60I, S68G, K122P, D123E, I135V, K173T, Q174K, D177E, G196E, Q207E, R211K, F214L, E224D, L228Q, V245K, D250E, A272P, K281R, A288S, E291D, V292I, I293V, E297A, L301MF
Meixenberger (2014)11-0136811-01368KJ771512NoneNone  V35T, K43N, V60I, S68G, K104KR, K122R, D123E, I135T, I142IT, S162HY, K173D, Q174K, D177E, I178L, T200A, Q207A, R211K, V245Q, E248N, A272P, T286A, E291DF
Niculescu (2014)DU5390DU5390KJ194792NoneNone  S48SP, K49R, V60I, S68G, K104R, V106I, D123E, S162H, K166Q, E169Q, Q174K, D177E, I195L, T200A, Q207E, V245Q, E248N, A272P, E291D, V292I, I293V, E297T, I326VF
 DU910DU910KJ194751NoneNone  V35T, K49R, V60I, S68G, V106I, D123E, I135T, S162H, K166Q, Q174K, D177E, I195L, T200A, Q207E, V245Q, E248N, A272P, E291D, V292I, I293V, E297T, V317A, I326VF
 DU3559bhDU3559bhKJ194822NoneNone  I5M, E6K, T39A, E40D, K49R, V60I, S68G, V106I, D123E, I135T, S162H, K166Q, E169K, K173E, Q174R, D177E, I178V, I195L, T200TA, Q207E, V245Q, E248N, A272P, E291D, V292I, I293V, E297A, K311KQR, I326VF
 DU2922bhDU2922bhKJ194814NoneNone  V35T, E40D, K49R, V60I, S68G, V106I, D123E, I135T, S162H, K166Q, E169K, K173E, Q174R, D177E, I178V, I195L, T200A, Q207E, V245Q, E248N, A272P, E291D, V292I, I293V, E297A, I326IVF
 DU461DU461KJ194746NoneNone  V35T, T39A, E40D, V60I, S68G, K104KR, V106VI, D123E, S162H, K166Q, Q174K, D177E, I195L, T200A, Q207E, R211RK, V245Q, E248DN, A272P, K277KR, T286A, E291D, V292I, I293V, P294T, E297T, I326IV, I329IVF
 DU1652DU1652KJ194759NoneNone  V35T, K49R, V60I, S68G, V106I, D123E, I135T, S162H, K166Q, Q174K, D177G, T200A, Q207E, V245Q, E248N, A272P, E291D, V292I, I293V, E297A, I326VF
 DU2593bhDU2593bhKJ194805NoneNone  V35T, E40D, K49R, V60I, S68G, K104R, V106I, D123E, S162H, K166Q, E169A, Q174K, D177E, I195L, T200A, Q207A, R211K, V245Q, E248N, A272P, E291D, V292I, I293V, E297T, I326VF
 DU772DU772KJ194804NoneNone  V35T, E40D, K49R, V60I, S68G, K104R, V106I, D123E, S162H, K166Q, Q174K, D177E, I195L, T200A, Q207E, V245Q, E248N, A272P, E291D, V292I, I293V, E297A, I326VF
 DU5323DU5323KJ194790NoneNone  V35T, T39A, V60I, S68G, K104R, V106I, D123E, I135L, S162H, K166Q, Q174K, D177E, I195L, T200A, Q207E, V245Q, E248N, A272P, G273R, E291D, V292I, I293V, E297T, I326VF
 DU3044DU3044KJ194777NoneNone  V35T, E40D, K49R, V60I, S68G, K104R, V106I, D123E, S162H, K166Q, Q174K, D177E, I195L, T200A, Q207E, L228F, V245Q, E248N, A272P, E291D, V292I, I293V, E297T, I326IV, I329IVF
 DU2087DU2087KJ194760NoneNone  V35T, K43N, V60I, S68G, D123E, I135T, S162F, K173E, Q174K, D177E, I178L, T200A, Q207N, R211K, V245Q, E248N, A272P, V276I, T286A, E291D, V292I, I293V, P294S, E297T, A304E, K311R, D324E, A327VF
 DU2880DU2880KJ194798NoneNone  K49R, V60I, S68G, V106I, D123E, I135T, S162H, K166Q, Q174K, D177E, I195L, T200A, Q207G, V245Q, E248D, V261I, A272P, T286A, E291D, V292I, I293V, E297A, I326VF
 DU3436bhDU3436bhKJ194818NoneNone  L12G, V35T, E40D, K49R, V60I, S68G, V106I, D123E, I135T, S162H, K166Q, Q174K, D177E, I195L, T200A, Q207E, V245Q, E248N, A272P, T286A, E291D, V292I, I293V, E297A, I326MF
 DU2837DU2837KJ194766NoneNone  V35T, E40D, K49R, V60I, S68G, V106I, D123E, S162H, K166Q, Q174K, D177G, V179VG, I195IL, T200A, Q207E, V245Q, E248N, A272P, E291D, V292I, I293V, E297A, I326VF
 DU1903DU1903KJ194803NoneNone  V35T, E40D, K49R, V60I, S68G, V106I, D123E, I135T, S162H, K166Q, E169K, K173E, Q174R, D177E, I178V, I195L, T200A, Q207E, V245Q, E248N, A272P, E291D, V292I, I293V, E297A, I326VF
 DU2673bhDU2673bhKJ194809NoneNone  K13M, D17A, V21S, Q23L, V35T, E40D, V60I, S68G, K104R, V106I, D123E, S162H, K166Q, Q174R, D177E, I195L, T200A, Q207E, V245Q, E248N, A272P, E291D, V292I, I293V, E297A, I326VF
 DU281DU281KJ194741NoneNone  V35T, E40D, K49R, Y56N, N57K, V60I, S68G, V106I, D123E, I135T, S162H, K166Q, Q174E, D177G, T200A, Q207E, V245Q, E248N, N265NK, A272P, E291D, V292I, I293V, E297A, K311N, I326VF
 DU3721bhDU3721bhKJ194828NoneNone  V35T, E40D, K49R, V60I, S68G, K104R, V106I, D123E, S162H, K166Q, K173R, Q174K, D177E, I195L, T200A, Q207E, V245Q, E248N, A272P, E291D, V292I, I293V, E297T, E312Q, I326VF
 DU3041DU3041KJ194776NoneNone  V35T, E40D, K49R, V60I, S68G, V106I, D123E, I135T, S162H, K166Q, Q174K, D177E, I195L, T200A, Q207E, F214L, V245Q, E248N, A272P, E291D, V292I, I293V, E297T, I326VF
 DU3589bhDU3589bhKJ194823NoneNone  V35T, E40D, K49R, V60I, S68G, V106I, D123E, I135T, S162H, K166Q, Q174K, D177G, T200A, Q207E, V245Q, E248N, A272P, E291D, V292I, I293V, E297A, V317A, A327AVF