<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype F
Gene RT
Mutation E44D
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 4
Patients 5
Isolates 5
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Dumans (2004)223223AY390175AZT, DDI, 3TCNoneM41L, D67N, M184I, L210W, T215CY181VE44D, V118I, D123E, I135V, S162C, K173A, Q174K, N175Y, V179I, T200A, E203K, Q207E, H208Y, R211KF
Machado (2004)cs150cs150AY313420AZT, DDINoneM41L, D67N, L210W, T215Y T39R, K43E, E44D, K49R, S162C, E169D, Q174K, Q207E, R211KF
Rodrigues (2005)BR0274502AY643224AZT, DDI, 3TC, D4TNoneM41L, V75M, M184V, L210W, T215Y P4S, V35T, T39L, E44D, V90I, V118I, K122E, I135V, S162Y, E169D, K173A, Q174K, Q207E, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, E297T, V317AF
 BLF_Pat35BR03SP71AY643250DDC, AZT, 3TC, D4TNoneM41L, M184V, L210W, T215Y E6A, K20R, V35T, T39Q, E44D, K122E, I135V, S162C, E169D, K173A, Q174K, I178L, Q207E, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294T, E297AF
von Wyl (2010)18015601801560GQ848114AZT, 3TCNoneM41L, D67N, M184V, L210W, T215Y V35T, T39A, K43KE, E44D, V118VI, D123E, I135V, S162C, E169A, K173S, Q174K, G196GE, E203K, Q207D, R211K, V245Q, E248D, A272P, K275R, T286A, E291D, V292I, I293V, E297T, V317A, R356K, M357I, G359S, T377V, Q394L, K395R, E399D, A400TF