<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype F
Gene RT
Mutation T215F
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 5
Patients 10
Isolates 10
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Brindeiro (2002)TVGG18TVGG18AY145826AZT, 3TCNoneM41L, M184V, T215F K20R, V35T, T39A, E40D, K49R, I135V, E169D, K173T, Q174R, I178L, T200A, Q207E, H208Y, R211K, V245Q, E248D, A272P, K277R, T286A, A288T, E291D, V292I, I293V, E297V, S322TF
 TVGG21TVGG21AY145827AZT, DDI, 3TC, D4TNoneM184V, T215F E6N, V35T, S68G, V118I, K122E, K173I, Q174K, Q207E, R211K, F214L, V245Q, T253S, A272P, T286A, E291D, V292I, I293V, P294T, E297AF
 TVSP1TVSP1AY145830AZT, 3TC, D4TNoneM41L, M184V, T215F K22N, V35T, E44K, I135V, S162C, E169A, K173A, Q174K, Q207E, R211K, V245Q, E248D, A272P, T286A, V292I, I293V, E297TF
Machado (2004)cs121cs121AY313411AZT, DDINoneM41L, D67N, T69D, K70R, T215F K49R, K122E, S162C, K173T, Q174K, D177E, I178L, Q207E, R211KF
 cs128cs128AY313378AZT, DDI, 3TCNoneD67N, T69D, K70R, M184V, T215F, K219Q K49R, I135V, S162C, E169D, K173A, Q174K, I178L, T200A, R211AF
Montes (2004)MB_patBAR99_BAR710AJ577733AZT, DDI, 3TCNoneM184V, T215F V35T, K49R, I135L, S162C, E169D, K173A, Q174K, Q207E, R211K, T240AF
Non-B Workgroup (2005)BR37BR37AY901429AZT, DDINoneD67N, K70R, T215F K49R, I135V, S162C, E169D, K173A, Q174K, T200A, Q207E, R211KF
 PL4051769351 AZT, 3TC, D4T, DDINoneM41L, D67N, K70R, T215F, K219Q V35T, V60I, D123E, S162C, E169D, K173A, Q174K, I178L, E203D, Q207E, R211K, D218E, K223Q, L228H, V245Q, E248D, A272P, E291D, V292I, I293V, P294T, E297T, S322T, I329LF
Dumans (2009)RENA463RENA463FJ405129AZT, 3TC, D4T, DDINoneM41L, T215F V35T, V118I, K173T, Q174K, Q207E, R211K, V245Q, E248D, D250S, K281R, T286A, I293V, E297KF
 75PR75PRFJ405164AZT, 3TCNoneM41L, D67N, L74I, L210W, T215F, K219W P4S, V35T, T39M, K43Q, S162C, E169D, K173A, Q174K, I178L, I202V, Q207E, H208Y, R211K, K223Q, L228RF