<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype F
Gene RT
Mutation V118I
Rx RTI-naive
IncludeMixtures No
References 15
Patients 23
Isolates 23
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Soares (2003)BRP2398BRP2398AF527318NoneNone  I37L, T39R, K101R, V106I, V118I, I135C, S162C, E169D, K173A, Q174K, T200A, Q207K, R211K, F214L, E224GF
Eshleman (2004)ABB95ABB95AY444274NoneNone  V35T, T39A, V118I, K122R, D123E, I135IV, K173A, Q174K, D177E, I180V, Q207E, R211K, F214L, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297A, Q334HF
 3781137811AY444273NoneNone  V35T, T39R, V106I, V118I, S162C, E169A, K173T, Q174K, Q207E, R211RK, F214L, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, E297VF
Marechal (2006)JF_002JF_002DQ443550NoneNone  V35M, T39A, E40D, V106VI, V118I, K122EQ, D123DE, T139TA, K173T, Q174K, D177E, I178M, T200A, R211T, F214L, K220KN, W229WL, P236PHF
Gonsalez (2007)06HIV_06GU288763NoneNone  V35I, V118I, D123E, K173I, Q174K, Q207E, R211K, F214LF
 79HIV_79GU288768NoneNone  E6K, V35T, T39K, V118I, K122E, I135V, S162C, D177E, T200I, E204K, Q207E, F214L, V245Q, E248DF
Bartolo (2009)CSE12601AOCSE126EU068351NoneNone  V35T, I47N, V60I, V118I, K122E, D123E, K173I, Q174K, D177E, T200E, Q207A, R211K, F214L, V245Q, E248N, A272S, K281R, T286A, E291D, V292I, I293V, E297AF
 ML14301AOML143EU068425NoneNone  K20R, V35K, V60I, S117P, V118I, L120S, K122E, D123E, F130I, K173R, Q174K, T200A, Q207E, F214L, V245Q, A272P, T286A, E291D, V292I, I293V, E297AF
Cardoso (2009)BRGO3024BRGO3024FJ548805NoneNone  V35L, V118I, I135V, E138A, S162C, K173T, Q174K, G196GE, Q207D, R211K, F214LF
Castelbranco (2010)090026A090026AHM357745NoneNone  V60I, V106I, V118I, I135V, E138A, I142V, S162C, K173T, Q174K, D177G, T200A, Q207E, R211K, F214L, V245QF
Gaspareto (2012)MAM18MAM18TRHM752205NoneNone  G18X, V35T, T39L, V60I, V118I, T139S, K173A, Q174K, Q207E, R211K, F214LF
 SPO74SPO74TRHM752240NoneNone  V35T, T39L, I50V, V118I, K122E, I135T, S162C, E169A, K173T, Q174K, D177N, Q207E, R211K, F214LF
Alencar (2013)PE2-0008PE2-0008JQ237997NoneNone  V35T, E40D, V106I, V118I, D123E, I135V, S162C, E169D, K173A, Q174K, T200A, Q207E, R211K, F214LF
 RJ2-0053RJ2-0053JQ238042NoneNone  V35T, T39A, E40D, V106VI, V118I, K122E, I135T, E138A, S162C, E169D, R172K, K173T, Q174K, I202V, Q207E, L210M, R211RK, F214LF
 PE2-0102PE2-0102JQ238208NoneNone  V35T, T39R, E40D, V118I, D121H, K122KE, D123E, I135T, S162C, E169D, K173A, Q174K, D177E, I178V, Q207E, R211K, F214LF
Ferreira (2013)BR09SP534BR09SP534HM534040NoneNone  K20R, V35T, T39N, V60I, V118I, D123E, I135T, T165I, E169D, K173A, Q174R, I178L, V179A, T200A, Q207E, R211K, F214L, V245EF
Temereanca (2013)SR40SR40JX966516NoneNone  T7P, V21I, V35G, I37L, T39A, E40D, V60I, V118I, D123E, I135L, N136X, S162C, Q174R, I195L, G196K, T200I, Q207A, R211K, L228Q, V245Q, E248N, A272P, K277R, T286A, E291D, V292I, I293V, T296S, E297T, L303W, A304K, E305R, D324EF
Bartolo (2014)09AOHDP3309AOHDP33KF853715NoneNone V179DP4Q, K20R, E28EK, V35T, I50V, V118I, I135V, S162C, Q174K, N175H, D177E, T200A, Q207E, R211K, F214L, P243T, V245Q, K281R, T286A, E291DG, V292I, I293V, E297RF
 09AOHDP23709AOHDP237KF853673NoneNone  K20R, V35T, T39S, V60I, V118I, D123E, I135L, N136T, K154R, K173I, Q174K, D177E, V179VG, T200A, Q207E, R211K, F214L, P243S, V245Q, D250E, A272P, K281R, T286A, E291D, V292I, I293V, E297AF
Velasco-de-Castro (2014)05BRRJRS2605BRRJRS26KF922201NoneNone  E6K, V35T, Y56X, V118I, K122E, S162G, E169D, K173A, Q174K, I178L, Q207E, R211K, F214LF
Alexiev (2015)11BG128111BG1281KJ765481NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39M, V60I, V118I, I135T, K173L, Q174K, T200A, Q207E, R211K, F214L, V245QF
Guimaraes (2015)BRSP502-13BRSP502-13KP115465NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39L, V118I, K122E, E169D, K173T, Q174R, I178V, Q207D, R211K, F214LF
 BRSP433-12BRSP433-12KP115440NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39K, K43Q, K49R, V106I, V118I, D123EG, I135V, S162Q, E169D, K173T, Q174K, D177E, T200A, Q207E, R211K, F214LF