<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation V75I
Rx RTI-naive
IncludeMixtures No
References 10
Patients 14
Isolates 14
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Weidle (2001)PW_UG474PW_UG474AY901278NoneNoneV75I P4T, V35T, T39TA, K49R, I50V, V60I, D121Y, K122E, D123E, K126Q, I132L, I142V, Q174QK, D177E, Q207E, F214L, I244V, V245K, D250E, A272P, T286A, G335D, M357K, G359S, A360V, T377L, T386I, K388KR, K390R, A400TD
Gibb (2002)DMG1818_w0 NoneNoneV75I V35E, K49R, V60I, D121Y, K122E, I132L, K166R, D177E, I178M, T200I, Q207E, R211K, I244V, V245T, D250E, A272S, K277R, L282C, T286A, E297K, I326T, R356K, A360T, T377Q, T386I, K390RD
Hierholzer (2002)SU243SU243AY102500NoneNoneV75I V35T, T39A, E40D, K49R, V60I, K122E, I132L, I135T, D177E, I178M, V179A, T200A, Q207E, R211K, V245E, D250ED
Kassu (2007)ETH-G-230G-230AB285830NoneNoneV75I V35T, T39A, E40D, K49R, V60I, D121H, K122E, K126R, I132L, I135V, S162C, S163T, T165I, D177E, I178V, Q207E, F214L, V245K, D250ED
Eshleman (2009)K39436W207-156978FJ389084NoneNoneV75I A33V, V35T, I37M, T39K, I47IL, K49R, V60I, K122E, D177E, T200I, Q207E, R211K, V245K, D250E, A272S, K281R, L282C, T286AD
Towler (2010)439553-X439553-XHM037830NoneNoneV75I V8I, V35L, T39A, K49R, V60I, D121H, K122E, I132L, I178L, V179I, T200L, Q207G, R211K, P243PT, I244V, V245K, D250E, A272AS, K281R, T286A, E297K, I329VD
Hamers (2011)CP076300792CP076300792HQ995356NoneNoneV75I V35T, T39A, K49R, V60I, D121C, K122E, I132L, I135V, T139A, T165I, D177E, I178M, Q207E, R211K, I244V, V245K, D250E, A272P, K277KR, T286A, I293VD
 CP076301888CP076301888HQ995367NoneNoneV75I V35M, T39A, K49R, V60I, K122E, T165I, D177E, I178M, V179I, Q207E, V245K, D250E, A272P, K281R, T286A, I293V, P294QD
 CP076301893CP076301893HQ995372NoneNoneV75I V35L, T39A, K49R, V60I, D121Y, K122E, I132L, D177E, I178M, V179I, Q207E, K238R, I244V, V245K, D250E, A272P, K277R, T286AD
Frentz (2013)EHR-96853EHR-96853JX301133NoneNoneV75I V35M, T39A, K49R, V60I, D121H, K122E, I132L, I135V, I142IT, Q145H, T165I, E169ED, D177E, I178L, T200A, I202IV, Q207E, R211K, I244V, V245ED
Hawke (2013)2134587 H2134587HKC238060NoneNoneV75I V35T, T39A, K49KR, I50IV, V60I, K82R, D121Y, K122E, I132L, K166KR, D177E, V179A, Q207E, F214FL, V241VI, V245K, D250ED
 2299032522990325KC238076NoneNoneV75IV179DV35A, T39A, K49R, D121Y, K122E, K126Q, I132L, T165I, Q174R, D177E, Q197R, T200A, I202V, Q207E, F214L, V245R, E248D, D250ED
Lee (2014)MBA1460MBA1460KJ907139NoneNoneV75I P4T, V35A, T39TA, K49R, V60I, D121Y, K122E, D123G, K126P, I132L, T165I, D177E, I178L, G196KR, T200A, E204D, Q207E, F214FL, K238R, I244V, V245E, D250E, T286A, A327V, G335D, M357K, G359S, K366R, A371V, I375A, T377L, T386I, K390R, A400TD
 MBA1413MBA1413KJ907098NoneNoneV75I V35M, T39A, K49R, V60I, K101R, K122E, D123E, I132L, I135T, D177E, I178M, T200A, Q207ED