<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation S68N
Rx RTI-naive
IncludeMixtures No
References 7
Patients 10
Isolates 10
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Becker-Pergola (2000)501.045BPG501-045AF188501NoneNone  V35T, K49R, V60I, S68N, D121Y, K122E, R125K, G141E, K173T, D177E, I178IM, T200V, Q207G, R211K, E224ED, V245K, D250E, A272P, K277R, L282C, T286A, I293VD
Richard (2004)RN_Pat2RNJLT01AAY556772NoneNone  V35T, T39L, K49R, V60I, S68N, D121Y, K122E, R125K, D177E, I178M, V189I, T200MD
Vidal (2007)U191602BU.U1916AM260230NoneNone  V35K, T39A, K49R, V60I, S68N, D121Y, K122E, D177E, I178M, E194D, T200M, Q207G, R211K, K238R, V245Q, D250E, L260I, A272P, L282C, I293V, L303M, G335D, P345Q, F346Y, R356K, M357L, R358K, K374R, T377Q, S379C, K388R, K390R, E399G, A400T, E404DD
Eshleman (2009)B08298B607-156912FJ389062NoneNone  V35M, T39A, E40D, K43T, K49R, V60I, S68N, D121Y, K122E, D123E, I159V, D177E, G196E, T200I, Q207G, R211K, V245K, D250E, A272P, V276VI, K277KR, L282C, L283I, T286A, I293VD
Ndembi (2011)NTCPS732NTCPS732HQ702629NoneNone  V35I, K49R, S68N, V90I, D121Y, K122E, I142M, D177E, T200M, Q207GD
Lee (2014)MBA1325MBA1325KJ907013NoneNone  P4S, K11T, V35T, V60I, S68N, K104KR, D121Y, K122E, R125K, D177E, T200I, Q207E, R211K, V245E, D250E, A272P, K275R, K277R, L279I, L282C, L283I, T286A, I293V, P294PT, I329V, G335D, P345Q, F346HY, R356K, M357ML, I375IV, T377Q, S379C, K390R, A400TD
 MBA1150MBA1150KJ906848NoneNone  V35I, V60I, S68N, V118I, D121Y, K122E, I135T, A158S, T165I, E169D, T200I, Q207E, R211K, V245E, D250E, A272P, L282C, T286A, V292VI, I293V, E297K, I309L, K311R, G335D, P345Q, F346Y, R356K, M357V, T377Q, S379C, K390R, A400TD
 MBA1496MBA1496KJ907173NoneNone  V35T, T39A, E40D, K49R, V60I, S68N, D121H, K122E, I135T, I159V, T200A, Q207E, R211K, P243PS, I244IV, V245E, D250E, A272P, K277R, Q278N, L282C, L283I, I293V, E297A, K311R, I329V, G335D, P345Q, F346Y, R356K, A360T, T377Q, S379C, K388R, K390R, E399D, A400TD
 MBA1346MBA1346KJ907032NoneNone  V35T, T39K, K43E, K49R, V60I, S68N, D121Y, K122E, R125K, D177E, T200TI, Q207E, R211K, V245K, D250E, A272P, K277R, L282C, L283I, T286I, I293V, E297EA, R307RK, K311KR, S322A, G335D, P345Q, F346Y, R356K, T377Q, S379C, K390R, A400TD
Reynolds (2016)B105781R16B105781R16KX944663NoneNone  K20R, V35T, K49R, V60I, S68N, D121Y, K122E, R125K, S162A, D177E, I178M, V189I, Q207E, R211K, V245E, D250E, A272P, L282C, L283I, I293V, V317AD