<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation M41L
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 6
Patients 13
Isolates 13
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Rousseau (2000)MNR18MNRMP1263AJ405965DDC, AZT, D4T, 3TC, DDINoneM41L, D67N, L210W, T215Y V35T, T39D, K49R, V60I, V118I, K122E, I135T, E169D, D177E, G196E, I202V, Q207E, R211K, V245N, D250E, A272P, K277R, T286A, I293V, E297R, G335D, R356K, G359S, T377M, T386I, K390R, A400T, E404D, V435ID
Montes (2004)MB_patDOI00_DOI704AJ577882AZT, DDC, DDI, D4T, 3TC, ABCNoneM41L, D67N, K70R, V75M, M184V, L210W, T215Y, K219E V35T, E40F, K43E, V60I, V118I, D121H, K122E, I135T, S162A, D177E, Q207E, H208Y, R211K, K223Q, L228HD
 MB_patESTU01_ESTU702AJ577887DDC, AZT, 3TC, D4T, DDINoneM41L, D67N, L210W, T215Y, K219Q V35T, T39A, K49R, V60I, V118I, K122E, S134N, I135T, T139I, I142T, D177E, I178M, Q207ED
Richard (2004)RNJCR32RNJCR32AY556780AZT, 3TC, D4T, DDINoneM41L, D67N V35T, K49R, V60I, V118I, K122E, D123E, D177E, I178M, G196E, T200AD
 RNJCR01RNJCR01AY556804AZT, DDINoneM41L P4T, V35T, K49R, V60I, K104N, K122E, I135T, I142T, E169D, I178L, T200A, I202VD
 RNJCR02RNJCR02AY556778AZT, 3TC, DDINoneM41L, D67N, K70R V35T, T39L, E40D, E44D, V60I, K104R, V118I, D121Y, K122E, D177E, I178M, G196E, T200AD
 RNJCR23RNJCR23AY556779AZT, 3TC, D4T, DDINoneM41L, D67N K22N, K32R, V35T, E44D, V60I, V118I, D121H, K122E, A158G, D177E, I178M, T200ID
 RNJCR24RNJCR24AY556791D4T, 3TC, DDINoneM41L, V75T, M184V V35T, K49R, V60I, D121C, K122E, D177E, I178M, Q197E, T200ED
Non-B Workgroup (2005)IL105IL105bAY901747AZT, 3TC, D4T, DDINoneM41L, D67DN, M184V, T215Y V60I, K122E, D123E, G152GS, W153R, D177E, I178L, E194EK, G196E, R199*, Q207E, P225PT, V245TD
 TK4014TK4014 AZT, 3TC, ABCNoneM41L, D67N, M184V, L210W, T215Y V35T, E44D, K49R, V60I, T69S, K122E, D123S, I135KR, S162X, D177E, I178M, V179VI, T200I, Q207E, R211RK, V245EK, D250E, A272P, K277R, L282C, L283I, A288AT, I293V, E297KD
 TK5013TK5013a AZT, 3TC, D4TNoneM41L, D67N, T69D, M184V, L210W, T215YA98GV35I, E44D, S48E, V60I, V118VI, D121H, K122E, D177E, T200IL, I202IV, Q207E, R211K, V245K, A272P, K281KR, L282C, T286A, I293V, D324ED
von Wyl (2007)1285248038EF449884NRTINoneM41L, D67N, T215Y V35T, E36D, E40D, K43R, K49R, V60I, K122E, D177E, T200I, Q207E, R211KD
von Wyl (2010)47967344796734GQ848131AZT, 3TCNoneM41L, D67N, K70R, M184V, L210W, T215Y, K219E V35T, V60I, K101R, K122E, D123N, I135T, K166R, D177E, E203K, Q207E, R211K, V245K, D250E, A272P, Q334D, Y342F, M357A, T369A, S379G, K385R, K390R, K395RD