<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation E40A
Rx RTI-naive
IncludeMixtures No
References 6
Patients 6
Isolates 6
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Baker (2007)A1050MBA1050-171005EF186216NoneNone  V35T, T39K, E40A, K43E, V60I, D121H, K122E, D123E, I142T, K166R, D177E, I178M, T200A, Q207E, R211K, V245E, E248D, D250E, A272P, K275Q, K277R, Q278H, L282C, I293VD
Ndembi (2008)IAEM075IAEM075EU306792NoneNone  V35T, E40A, K43T, K49R, V60I, D121Y, K122E, D177E, Q197K, T200I, Q207GD
Aghokeng (2009)CYV020CYV020GU191590NoneNone V179DV35T, E40A, K43E, K49R, V60I, R78RK, V118I, K122P, I135T, T139S, T165I, D177E, I178L, I195L, T200A, E204N, Q207E, F214L, E224EK, V245T, D250E, A272P, T286A, K311R, I329V, Q334K, Y339W, M357T, T386I, K390R, A400T, T403MD
Eshleman (2009)H15006W207-156959FJ389078NoneNone  E6EK, V35T, T39I, E40A, V60I, D121Y, K122E, D177E, I178M, E194D, T200I, Q207E, R211K, V245K, D250E, A272P, K275LQ, K277KR, L282C, T286A, I293V, E297KD
Descamps (2010)508odyssee508odysseeHQ718341NoneNone  E40A, K43E, K49R, V60I, V106I, V118I, K122E, I135V, T139S, S162C, T165I, E169ED, D177E, I178L, Q207E, R211K, F214LD
Hamers (2011)CP076302322CP076302322HQ993863NoneNone  V35T, E40A, K43E, K49R, V60I, D121H, K122E, I135R, K173KR, D177E, I178LM, V179I, T200I, Q207G, R211K, V245K, D250E, A272P, V276T, L282C, L283I, T286A, I293VD