<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation G333E
Rx RTI-naive
IncludeMixtures No
References 11
Patients 15
Isolates 15
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Arroyo (2004)01TZA28001TZA280AY253311NoneNone  E6A, V35T, K49R, V60I, I135T, D177E, Q207D, R211K, V245K, D250E, A272S, T286A, E297K, K311R, P313T, V317A, G333E, R356K, A360T, T377L, S379G, T386I, K390R, A400T, V435I, K451R, R461K, H483N, V496I, A554SD
Eshleman (2004)ABB208ABB208AY444271NoneNone  V35T, T39A, E40D, K49R, V60I, R83K, D123E, I135T, T139S, S162C, R172K, D177E, I178L, V179T, Q182AS, T200A, E204K, Q207E, R211K, F214L, V245T, S251D, A272P, K281R, T286A, V292I, E297K, K311R, D324E, I329V, G333E, Q334ED
Kijak (2004)0175BA01CM.0175AY371156NoneNone  V35T, K49R, I135T, S162C, R172K, D177E, I178L, V179I, Q182S, T200I, E204K, Q207E, R211K, F214L, V245T, E248D, A272P, K277R, T286A, E297K, K311R, I329V, G333E, Q334E, Y339W, M357I, G359S, A376T, T377M, K390R, T403M, V435I, R461K, S468P, L469F, H483N, L491S, E492K, A554SD
Snoeck (2004)BE28BE28AY901290NoneNone  V35I, K49R, V60I, V118I, D121C, K122Q, D123X, E169D, D177E, I178M, I195IL, T200A, E204K, Q207E, R211K, F214L, V245T, D250E, S251D, K277R, T286A, V292I, I293V, E297Q, I329L, G333E, Q334HD
Vidal (2006)NV_KIST10302.KIST103AM041026NoneNone  M16L, K20R, V35T, K49R, V60I, V118I, D121C, K122E, E169D, D177E, I178L, T200A, E204K, Q207E, R211K, F214L, V245T, D250E, A272P, T286A, V292I, I293V, E297Q, I329L, G333E, Q334Y, M357R, K390R, V435ID
 NV_MBFE25202.MBFE252AM041024NoneNone  V35T, K49R, V60I, V118I, D121C, K122E, T165I, E169D, D177E, I178M, T200A, E204K, Q207E, R211K, F214L, V245T, D250E, A272P, T286A, V292I, I293V, I329L, G333E, Q334Y, M357R, K390R, V435ID
Church (2007)055-111458T055EF612006NoneNone  V35T, K49R, V60I, K122E, D123S, I142V, D177E, I178M, T200A, E204K, Q207E, R211G, V245K, D250E, A272P, K277KR, T286A, E297K, G333ED
 553-130284W553EF612063NoneNone  V35I, E40D, K49R, V60I, K102Q, D121Y, K122E, I135T, S162H, D177E, I178M, T200A, E204EK, Q207E, V245K, D250E, A272P, K277R, T286A, I293V, R307K, G333E, Q334YD
Nyombi (2008)TMS120TMS120EU251820NoneNone  V35T, K49R, V60I, K122E, D123S, E169D, D177E, I178M, T200TI, Q207E, R211K, K238R, V245K, D250E, A272P, K277R, L282C, L283I, I293V, G333E, G335D, P345Q, F346Y, R356K, M357LD
Djoko (2010)667CD3864FR666667NoneNone  I5V, V35T, V60I, V118I, K122Q, I135V, I142V, E169D, D177E, T200A, E204D, Q207E, R211K, F214L, V245T, D250E, V276VI, K281R, T286A, V292VI, I293IV, P294PS, E297K, I329L, G333E, Q334H, M357MVD
Youngpairoj (2012)cm182bbcm182bbDQ166435NoneNone  P4H, V21I, V35T, T39G, K49R, I135T, S162C, R172K, D177E, I178L, Q182S, E204N, Q207E, R211K, F214L, V245T, E248N, K249Q, D250E, A272P, K277R, T286A, E297K, G333E, Q334A, G335C, Y339W, R356K, M357V, Q373H, K374R, K390R, T403K, K431T, V435ID
Kemal (2013)71017101JQ364514NoneNone  V35T, T39R, V60I, K102Q, D121Y, K122E, I135T, S162C, D177E, I178M, T200A, Q207E, P243A, V245K, S251I, A272P, K277R, T286A, I293V, E297V, I329L, G333E, R356K, T377Q, S379C, K390R, A400TD
Lee (2014)MBA1343MBA1343KJ907029NoneNone  V35T, E40ED, K43KR, K49R, V60I, D121Y, K122E, D177E, I178M, T200IM, Q207E, R211K, P243AS, V245EK, D250E, A272P, K277KR, K281KR, L282C, T286A, I329V, G333E, P345Q, F346Y, R356K, M357MIT, A360I, A371V, A376S, T377Q, S379C, K390RD
 MBA1377MBA1377KJ907063NoneNone  P4T, E6D, V35T, T39TA, S48T, K49KR, V60I, D121Y, K122E, D177E, T200I, Q207E, R211K, L228H, V245Q, E248D, D250E, A272S, V276I, K277R, L282C, L283I, P294T, I329V, G333E, G335N, P345Q, F346Y, R356K, M357V, T377Q, S379C, K390RD
 MBA1341MBA1341KJ907027NoneNone  V35T, E40D, I47IL, K49R, I50V, V60I, K122E, D123H, D177E, I178M, T200I, Q207E, R211RK, V245K, K249Q, D250E, A272P, K281R, L282C, T286A, A288T, I293V, P294T, E297K, L310I, G333E, G335D, P345Q, F346Y, R356K, A360T, E370G, T377Q, S379C, T386I, K390RD