<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation T215Y
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 12
Patients 14
Isolates 14
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Carr (1999)SE7108SE7108AF071473AZT, DDINoneD67N, K70R, T215Y, K219Q V35T, V60I, D121H, K122E, D123E, I135T, K173S, Q174K, D177E, I178L, V179I, T200I, Q207E, R211K, K238R, V245K, D250E, L282C, T286A, V292I, I293V, G335D, T338S, P345Q, F346Y, R356K, M357L, A360T, V365I, E370A, T377Q, S379C, K390R, A400T, E432D, V435A, A437V, V458I, H483N, L491P, K512R, S519N, Q524K, K527G, E529D, A534S, A554SD
Rousseau (2000)MNR18MNRMP1263AJ405965DDC, AZT, D4T, 3TC, DDINoneM41L, D67N, L210W, T215Y V35T, T39D, K49R, V60I, V118I, K122E, I135T, E169D, D177E, G196E, I202V, Q207E, R211K, V245N, D250E, A272P, K277R, T286A, I293V, E297R, G335D, R356K, G359S, T377M, T386I, K390R, A400T, E404D, V435ID
Si-Mohamed (2000)AS_BIAAS_BIAAF199239AZTNoneT215Y K49R, V60I, D121Y, K122E, D123E, I142V, D177E, I178M, Q207ED
Weidle (2001)PW_UG458PW_UG458a AZT, DDINoneM41ML, L210LW, T215Y V35T, V60I, D121C, K122E, D177E, I178M, T200M, Q207G, R211K, V245K, D250E, A272P, K277R, Q278H, L282C, L283I, V292I, I293V, G335D, P345Q, F346Y, R356K, G359GS, A360T, T377Q, S379C, K390R, A400TD
Cuevas (2002)CU40CU40AF425421AZTNoneT215Y V35T, T39A, K49R, V60I, S68G, K122E, I135T, T139A, E169D, D177E, Q207ED
Vergne (2003)VL01SN55HPD01SN55AJ583749DDC, AZTNoneD67N, T215Y, K219R V35T, V60I, K104R, D121Y, K122E, D177E, I178V, E203K, Q207E, R211K, K223E, V245T, D250E, A272P, K277R, Q278N, A288T, E297K, I329L, T369A, A376T, T377Q, K390R, A400T, T403I, E404DD
Non-B Workgroup (2005)TK4014TK4014 AZT, 3TC, ABCNoneM41L, D67N, M184V, L210W, T215Y V35T, E44D, K49R, V60I, T69S, K122E, D123S, I135KR, S162SAGT, D177E, I178M, V179VI, T200I, Q207E, R211RK, V245EK, D250E, A272P, K277R, L282C, L283I, A288AT, I293V, E297KD
 TK4016TK4016 AZT, 3TCNoneM184V, L210W, T215Y I31R, V35I, K49R, V60I, K122E, D123S, I135L, D177E, I178M, T200V, Q207E, R211K, V245E, D250E, A272P, L282C, L283I, T286A, I293V, D324E, Q334RD
 TK5013TK5013a AZT, 3TC, D4TNoneM41L, D67N, T69D, M184V, L210W, T215YA98GV35I, E44D, S48E, V60I, V118VI, D121H, K122E, D177E, T200IL, I202IV, Q207E, R211K, V245K, A272P, K281KR, L282C, T286A, I293V, D324ED
Weber (2005)F86075F86075AY677601ABC, AZT, 3TCNoneD67N, K70R, M184V, T215Y V21VI, V35T, E40D, K49R, I50V, V60I, K101KQ, K122E, E169D, Q207E, V245K, D250E, A272PD
von Wyl (2007)1285248038EF449884NRTINoneM41L, D67N, T215Y V35T, E36D, E40D, K43R, K49R, V60I, K122E, D177E, T200I, Q207E, R211KD
Ndembi (2010)16496D_P116496GQ409586ABC, AZT, 3TC, D4TNoneL74V, Y115F, M184V, T215YK103NV35T, K49R, V60I, K122E, D177E, I178M, T200I, Q207E, R211KD
von Wyl (2010)47967344796734GQ848131AZT, 3TCNoneM41L, D67N, K70R, M184V, L210W, T215Y, K219E V35T, V60I, K101R, K122E, D123N, I135T, K166R, D177E, E203K, Q207E, R211K, V245K, D250E, A272P, Q334D, Y342F, M357A, T369A, S379G, K385R, K390R, K395R, A400TD
Inzaule (2013)410410JQ914067ABC, AZTNoneM184MV, T215Y V35T, K43R, V60I, D121Y, K122E, I142V, D177E, T200I, Q207G, R211KD