<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation V118I
Rx RTI-naive
IncludeMixtures No
References 26
Patients 48
Isolates 48
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Gao (1998)84ZR08584ZR085U88822NoneNone  V35T, E40D, K49R, V60I, V106I, V118I, D121C, K122E, T165I, D177E, I178V, T200A, E204K, Q207E, F214L, P243S, V245T, D250E, A272P, V314M, I329L, T377I, K390R, A400T, T403I, E404D, V435I, R448K, S468P, L469F, H483N, A554SD
Vergne (2000)LVMP634LVMP634AJ286968NoneNone  P4T, K11T, V35A, K49R, V118I, I135T, S162C, R172K, D177E, I178L, V179I, Q182S, T200I, Q207N, R211K, F214L, V245T, E248D, D250E, A272P, T286A, E297K, K311R, I329V, Q334E, G335S, Y339W, G359S, K390R, T403RD
Hierholzer (2002)SU480SU480AY102483NoneNone  V35T, T39A, V60I, V118I, D123E, I135T, T165I, D177E, I178L, I202V, Q207E, R211K, F214L, V245E, E248D, D250ED
Pandrea (2002)IP_98CIRMF1098CIRMF10AY140610NoneNone  E6D, V35T, V60I, T107S, V118I, D121C, K122E, I142V, T165I, D177E, I178V, T200A, E204K, Q207E, R211K, F214LD
 IP_97CIRMF0897CIRMF08AY140611NoneNone  E6D, V35T, T39L, V60I, T107S, V118I, D121Y, D177E, I178L, T200A, E204K, F214LD
 IP_97CIRMF2697CIRMF26AY140613NoneNone  V35T, T39I, V60I, T107S, V118I, D121C, K122E, I135V, T165I, D177E, I178V, T200A, E204K, F214LD
 IP_97CIRMF2797CIRMF27AY140614NoneNone  V35T, E40D, K49R, V60I, V106I, V118I, T165V, D177E, I178L, V189I, E204K, Q207E, F214LD
Gonzalez (2003)PG_GT1138GT1138AF529943NoneNone  V35T, E40D, K49R, V60I, V118I, K122T, T165I, D177E, I178L, E204K, Q207E, F214L, V245TD
 PG_GT576GT576AF529945NoneNone  V35T, E40D, K49R, V60I, V118I, I135T, T165I, D177E, I178L, T200I, E204K, Q207E, F214L, V245TD
 PG_GT598GT598AF529946NoneNone  V35T, K49R, V60I, V118I, T165I, E169D, D177E, I178L, E204K, Q207E, F214LD
 PG_GT970GT970AF529952NoneNone  V35T, E40D, K49R, V60I, V118I, K122T, Q145W, T165I, D177E, I178L, T200A, E204K, Q207E, F214L, V245TD
 PG_GT995GT995AF529954NoneNone  V35T, E40D, K49R, V60I, V118I, K122P, E138G, D177E, I178L, E204N, Q207E, F214L, V245T, E248DD
Snoeck (2004)BE28BE28AY901290NoneNone  V35I, K49R, V60I, V118I, D121C, K122Q, D123X, E169D, D177E, I178M, I195IL, T200A, E204K, Q207E, R211K, F214L, V245T, D250E, S251D, K277R, T286A, V292I, I293V, E297Q, I329L, G333E, Q334HD
Marechal (2006)JF_136JF_136DQ443617NoneNone  V35T, E36EA, T39M, V60I, V118I, K122E, T165TI, D177E, I178M, Q207A, F214L, K238R, V245TD
Niama (2006)ARV32ARV32FM164886NoneNone  P4T, E6D, V35T, V60I, W88C, T107S, V118I, D121C, K122E, I135V, I142V, S162A, D177E, I178V, T200A, E204K, Q207D, R211K, F214L, V245T, E248D, D250E, A272S, R284K, T286A, I293V, I329L, E344D, M357V, A360T, A376S, T386I, K390R, E404DD
Vergne (2006)LV_02CM-CK1_1802CM-18AM181793NoneNone  V21I, V35T, T39E, S48T, V60I, V118I, K122E, I135T, E138A, T139A, I142V, S162C, R172K, D177E, I178L, V179T, Q182S, G196E, T200A, E204K, Q207E, R211K, F214L, I244V, V245T, D250E, A272P, K275Q, T286A, E297K, K311R, S322ST, I329V, Q334E, T338S, Y339W, I341V, R356K, K374R, K390R, E399D, T403MD
Vidal (2006)NV_KIST10302.KIST103AM041026NoneNone  M16L, K20R, V35T, K49R, V60I, V118I, D121C, K122E, E169D, D177E, I178L, T200A, E204K, Q207E, R211K, F214L, V245T, D250E, A272P, T286A, V292I, I293V, E297Q, I329L, G333E, Q334Y, M357R, K390R, V435ID
 NV_MBFE25202.MBFE252AM041024NoneNone  V35T, K49R, V60I, V118I, D121C, K122E, T165I, E169D, D177E, I178M, T200A, E204K, Q207E, R211K, F214L, V245T, D250E, A272P, T286A, V292I, I293V, I329L, G333E, Q334Y, M357R, K390R, V435ID
Baker (2007)0351NG04-0351NGAY803476NoneNone V179DE6K, V35T, T39TI, V60I, V106I, V118I, K122E, D177E, I178M, Q197E, Q207E, F214L, V245E, D250E, A272P, T286A, I293V, S322AD
Caron (2008)2340Gab2340RTEU556447NoneNone  V60I, T107S, V118I, D121C, I142V, T165I, K173E, D177E, I178V, T200A, E204K, Q207E, F214LD
Ndembi (2008)CMYD-2404CMYD-24DQ990397NoneNone  K11E, P14T, V35T, V60I, V106I, V118I, D121Y, K122E, I135T, E138A, S162C, R172K, E204K, Q207E, F214L, E224DD
 CMYD-5704CMYD-57DQ990422NoneNone  P4T, V35T, E40D, K49R, V60I, V118I, T139S, S162C, E169D, D177E, I178L, G196E, T200A, E204K, Q207E, R211K, F214L, H221P, Q222E, K223RD
Aghokeng (2009)CYV020CYV020GU191590NoneNone V179DV35T, E40A, K43E, K49R, V60I, R78RK, V118I, K122P, I135T, T139S, T165I, D177E, I178L, I195L, T200A, E204N, Q207E, F214L, E224EK, V245T, D250E, A272P, T286A, K311R, I329V, Q334K, Y339W, M357T, T386I, K390R, A400T, T403MD
 CYN1003CYN1003GU191593NoneNone  K11Q, P14A, V35T, E40D, V60I, V118I, K122P, D123K, T139S, S162C, D177E, I178L, V179I, E204K, Q207E, F214L, V245T, D250E, A272P, K277GR, T286A, E297K, Y339W, M357T, A376S, T377M, K390R, T403MD
Bartolo (2009)HDC23801AOHDC238EU068370NoneNone  V35T, V60I, F87L, V106I, V118I, D121C, K122E, D177E, Q207E, R211K, F214L, V245T, D250E, A272P, T286AD
Vercauteren (2009)pt14794406987634GQ399545NoneNone  P4T, E6D, V35T, K49R, V60I, V118I, K122KE, I135AT, D177E, T200A, Q207N, R211K, F214L, V245Q, D250E, K277R, K281KR, T286A, A288AS, A327SD
 pt6848994198547GQ400340NoneNone  P4T, E6D, V35T, K49R, I50IV, V60I, V118I, D123N, I135V, D177E, T200A, Q207N, R211K, F214L, V245Q, D250E, K275Q, K281R, T286A, A327SD
Descamps (2010)508odyssee508odysseeHQ718341NoneNone  E40A, K43E, K49R, V60I, V106I, V118I, K122E, I135V, T139S, S162C, T165I, E169ED, D177E, I178L, Q207E, R211K, F214LD
Djoko (2010)655CD2193FR666655NoneNone  V35T, V60I, D86DE, V118I, D121C, K122E, F171Y, Q174K, D177E, I178V, G196E, T200A, Q207E, R211K, F214L, V245T, P247A, K249Q, A272P, K277KR, T286A, E297K, D324E, I329L, G335D, M357K, K366RD
 667CD3864FR666667NoneNone  I5V, V35T, V60I, V118I, K122Q, I135V, I142V, E169D, D177E, T200A, E204D, Q207E, R211K, F214L, V245T, D250E, V276VI, K281R, T286A, V292VI, I293IV, P294PS, E297K, I329L, G333E, Q334H, M357MVD
 675CD4647FR666675NoneNone  K11R, K13KR, V35T, E40ED, K49R, V60I, V118I, K122E, D123DN, E169D, D177E, I178V, G196S, T200A, Q207E, F214L, V245T, E248D, D250E, L260LV, A272S, K277R, T286A, I293V, K311R, I329L, T338TS, M357MID
Soares (2010)CM04_050CM04_050GU366145NoneNone  P4T, E6D, V35T, K49R, V118I, K122E, I135T, S162C, R172K, D177E, I178L, V179I, Q182S, Q207E, R211K, F214L, V245T, D250ED
Aghokeng (2011)HJ1611HJ1611JN639523NoneNone  P4T, I5IV, V35T, E40D, K49R, V60I, V118I, K122E, I135IV, T139S, S162C, E169D, D177E, I178L, T200A, I202V, E204K, Q207E, F214L, V245T, E248D, A272P, K277KR, K281KR, T286A, E297KR, K311KR, Y339WD
 SK3032-PISK3032-PIJN639528NoneNone  V35T, E36A, K49R, V60I, V118I, D123N, I135T, Q145E, S162C, E169D, R172K, D177E, I178L, T200A, E204IM, Q207E, F214L, V245E, D250T, A272P, V276I, T286A, A288AT, I293IV, E297K, I329V, Q334LD
 SK1002-PISK1002-PIHQ864352NoneNone  V35T, E40D, S48SP, K49R, V60I, V118I, K122E, D123E, I135T, E138A, S162C, E169ED, R172K, Q174QR, D177DE, I178L, Q182S, T200E, Q207E, R211K, F214L, P243T, V245T, D250E, A272P, K275R, V276T, Q278HN, K281KR, T286A, P294PS, E297K, A304E, K311RD
Hamers (2011)CP076304185CP076304185HQ993896NoneNone K101E, E138KP4T, V35T, E40D, K43KR, K49R, V60I, V118I, K122E, I142V, E169DGNS, D177E, I178IMV, G196E, I202V, Q207E, R211K, F214L, V245E, E248D, D250E, L282C, L283I, I293VD
 CP076303519CP076303519HQ994001NoneNone  V35T, V60I, V118I, D121H, K122E, T165I, Q174E, D177E, I178V, T200A, E204K, Q207E, R211K, F214L, P243A, V245T, D250E, A272P, K281R, I293V, P294T, E297RD
Frange (2012)930213EVT930213EVTJQ292229NoneNone  K49R, E53D, V60I, V118I, K122Q, S162D, T165V, E169D, D177E, I178L, V189I, T200A, E204K, Q207E, F214L, V245TD
Billong (2013)MR001MR001KF192112NoneNone  V35T, T39K, K43E, K49R, V60I, V106VI, V118I, I135T, E138A, T139A, S162CDGY, R172K, K173E, D177E, I178L, V179I, Q182S, G196E, T200A, E204K, Q207E, R211K, F214L, P243S, V245T, D250E, A272P, K277R, T286A, I293ILV, P294PS, E297R, K311R, I329IV, Q334DD
 MR058MR058KF192254NoneNone  V35T, E40D, S48ST, K49R, I50IV, V60I, P95PS, V118I, D123E, T139S, S162C, D177E, I178L, D186DE, E204EK, Q207E, F214L, V245T, D250ED
 MR091MR091KF192255NoneNone  E6K, K20R, V35T, E40D, K49R, V60I, V118I, P119PL, K122P, D123DN, T165I, K166KR, N175NS, D177E, I178L, T200A, K201KR, E203DG, E204K, Q207E, F214LD
 MR019MR019KF192114NoneNone  V35T, T39TAS, K49R, V60I, V106VI, V118I, K122Q, I142V, T165I, D177E, I178L, E204K, Q207E, R211G, F214L, V245T, D250DE, A272P, T286TA, I293V, V317A, I329VD
Masimba (2013)TZ173TZ173KC537109NoneNone  K49R, I50V, V60I, V106I, V118I, D121C, K122E, T165I, D177ED
Chung (2014)KTL_33_KA329eKTL_33_KA329eKF544255NoneNone  K20KR, V35T, T39M, K49R, V60I, K102R, V118I, K122KE, I135T, K173S, Q174K, V179I, T200K, Q207A, R211S, F214LD
 JGH36_RT485JGH36_RT485KF544178NoneNone  I5V, E6ED, V35I, V118I, D121Y, K122E, I135T, D177E, I178L, T200IM, Q207E, R211K, F214LD
Lee (2014)MBA1150MBA1150KJ906848NoneNone  V35I, V60I, S68N, V118I, D121Y, K122E, I135T, A158S, T165I, E169D, T200I, Q207E, R211K, V245E, D250E, A272P, L282C, T286A, V292VI, I293V, E297K, I309L, K311R, G335D, P345Q, F346Y, R356K, M357V, T377Q, S379C, K390RD
 AMU064AMU064KJ906682NoneNone  V35T, K49KR, V60I, K102Q, V118I, D121Y, K122E, R125K, S162C, N175H, D177E, V179VI, G196E, T200M, Q207EG, R211K, F214L, L228H, V245T, D250E, A272S, L282C, T286TA, I293V, K311KR, G335D, P345Q, F346Y, R356K, M357S, E370G, T377Q, S379C, K390RD
 MBA1392MBA1392KJ907078NoneNone  P4T, K11Q, V35I, V118I, D121HY, K122E, D123S, I135T, K166R, K173S, Q197K, T200A, Q207AD, R211K, F214L, V245Q, A272P, K277R, L282C, I293V, G335D, P345Q, F346Y, R356K, M357MI, G359S, A360T, A376T, T377Q, S379C, K390RD