<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype D
Gene RT
Mutation V118I
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 8
Patients 12
Isolates 13
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Rousseau (2000)MNR18MNRMP1263AJ405965DDC, AZT, D4T, 3TC, DDINoneM41L, D67N, L210W, T215Y V35T, T39D, K49R, V60I, V118I, K122E, I135T, E169D, D177E, G196E, I202V, Q207E, R211K, V245N, D250E, A272P, K277R, T286A, I293V, E297R, G335D, R356K, G359S, T377M, T386I, K390R, A400T, E404D, V435ID
Vergne (2002)LV19LV19AJ313419D4T, DDINone  E6D, V35T, E40A, K43E, V60I, V106I, V118I, D121C, K122E, T165I, D177E, I178V, T200E, E204K, F214L, V245T, E248D, D250E, A272P, K281R, R284K, I293V, I329L, G335S, A360T, K366R, A376S, T386I, K390R, E404DD
 LV02BLV02BAJ313404D4T, DDINone  V35T, K49R, V60I, V118I, K122E, T165I, D177E, I178L, T200A, E204K, Q207E, F214L, V245I, D250E, A272P, K275R, Q278E, T286A, E328D, I329V, Y339W, A360T, V381I, K390R, E399DD
Montes (2004)MB_patESTU01_ESTU702AJ577887DDC, AZT, 3TC, D4T, DDINoneM41L, D67N, L210W, T215Y, K219Q V35T, T39A, K49R, V60I, V118I, K122E, S134N, I135T, T139I, I142T, D177E, I178M, Q207ED
Richard (2004)RNJCR32RNJCR32AY556780AZT, 3TC, D4T, DDINoneM41L, D67N V35T, K49R, V60I, V118I, K122E, D123E, D177E, I178M, G196E, T200AD
 RNJCR02RNJCR02AY556778AZT, 3TC, DDINoneM41L, D67N, K70R V35T, T39L, E40D, E44D, V60I, K104R, V118I, D121Y, K122E, D177E, I178M, G196E, T200AD
 RNJCR23RNJCR23AY556779AZT, 3TC, D4T, DDINoneM41L, D67N K22N, K32R, V35T, E44D, V60I, V118I, D121H, K122E, A158G, D177E, I178M, T200ID
Delaunay (2005)DC_01818_2001w12DQ286508ABC, TDF, 3TCNoneM184IV179DV35T, E40D, K49R, E53D, V60I, V118I, K122Q, D123N, T165V, D177E, I178L, Q207E, F214LD
  18_2001w24DQ286509ABC, TDF, 3TCNoneM184V V35T, E40D, K49R, E53D, V60I, V118I, K122Q, D123N, T165V, D177E, I178L, E204N, Q207E, F214LD
Laurent (2006)CK2-8402CM-84AM279448AZT, DDI, D4T, 3TCNoneK65R, F116Y, Q151M, M184V V35T, S48E, K49R, V60I, K64R, S68R, V118I, D123E, R172K, D177E, I178L, Q182H, Q207E, R211K, F214L, V245T, D250E, A272P, T286A, I293V, I329V, Y339W, A360T, A376S, K390R, T403MD
Koyalta (2009)8TCHAD-8FJ688175D4T, 3TCNoneD67N, K70R, M184V, K219E V60I, V106I, V118I, T139S, T165I, D177E, I178L, K201R, E204K, Q207E, R211K, F214LD
 68TCHAD-68FJ688199D4T, 3TCNone  K49R, V60I, V118I, I135T, I142T, R172K, D177E, I178L, Q207E, F214LD
Fokam (2011)CIRCB-9860CIRCB-9860JQ796162AZT, 3TCNone  P4PT, K11Q, P14A, V35T, E40D, V60I, V118I, K122P, D123N, T139S, S162C, D177E, I178L, V179I, E204K, Q207E, F214L, V245T, D250E, A272P, K277R, T286AD