<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation K70R
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 7
Patients 7
Isolates 7
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Janssens (2000)WJ_VI1197WJ_VI1197AJ276596AZTNoneD67G, K70R, K219Q K20R, V35T, V60I, T69N, K103R, K122E, D123S, S162A, K173T, Q174E, D177K, T200A, E203D, Q207E, F214L, V245Q, K275R, T286A, E291D, V292I, I293V, P294T, S322G, D324E, G335D, R356K, M357R, R358K, G359S, T369V, A371V, I375V, I380V, K390R, K395R, T403R, E432D, V435A, V466A, D471E, Q480H, H483Q, L491S, K512R, S519N, Q524K, K527E, E529D, L533V, A534S, A554SCRF02_AG
Thomson (2001)MT-X230MT-X230AY017453AZT, DDC, DDI, 3TCNoneD67A, K70R, T215F P9K, K20R, V35T, E36D, T39S, T69S, D123E, S162A, K173T, Q174K, D177E, T200A, R211KCRF02_AG
Maxeiner (2002)430132430132+ AZT, D4TNoneK70R E6K, K20R, V35T, T39M, V60I, T69N, K122E, I135V, S162A, K173T, Q174N, D177E, I178M, T200A, Q207E, F214L, V245Q, T286A, E291D, V292I, I293V, P294T, I326V, G335D, R356RK, M357K, G359S, K366R, T369V, A371V, I375V, A376V, A400T, T403M, W410C, E432D, T470S, D471E, Q480H, L491S, K512R, S519N, Q524K, K527E, A534S, A554NCRF02_AG
Venturi (2002)GV-33GV-33.1AF517285DDINoneM41L, K70R I135V, S162A, K173T, Q174K, D177E, I178M, G196EV, T200A, E204KCRF02_AG
Vergne (2003)VL98SN46HALD00SN46AJ583747D4T, DDINoneK70R, K219E V35T, T39L, V60I, K122P, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245K, D250E, A272P, T286A, E291D, V292I, I293V, P294T, N306D, E312G, S322A, G335D, R356K, M357R, R358S, G359S, Q367P, E370Q, A371V, I375V, A376S, T377L, S379C, K390R, K395R, T403MCRF02_AG
Montes (2004)MB_patKES01_KES716AJ577920D4T, DDI, AZT, 3TCNoneM41L, D67N, K70R, T215Y V21I, V35T, V60I, K122P, I135V, S162A, K173T, Q174K, D177E, I178M, Q207E, R211KCRF02_AG
Holguin (2008)LP3801SP-LP38DQ926897AZT, 3TCNoneM41L, D67N, K70R, M184V V35T, E36D, V60I, K122E, D123S, I135V, S162A, K173A, Q174K, D177E, T200A, Q207ECRF02_AG