<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation M41L
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 9
Patients 15
Isolates 16
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Si-Mohamed (2000)AS_FANAS_FANAF199276D4T, 3TCNoneM41L, D67N, M184V, T215Y V60I, V118I, K122E, I135V, T139K, S162A, K166E, E169K, K173T, Q174A, D177E, I178M, T200A, E203K, Q207E, H208Y, R211KCRF02_AG
Venturi (2002)GV-33GV-33.1AF517285DDINoneM41L, K70R I135V, S162A, K173T, Q174K, D177E, I178M, G196EV, T200A, E204KCRF02_AG
Vergne (2003)VL98SN53HALD00SN53AJ583748AZT, DDI, D4TNoneM41L, D67N, L210W, T215Y K20R, V35M, K43E, V118I, A158S, T165I, K173A, Q174K, D177E, I178M, T200A, Q207E, V245Q, E248D, T286A, E291D, V292I, I293V, P294TCRF02_AG
Montes (2004)MB_patKES01_KES716AJ577920D4T, DDI, AZT, 3TCNoneM41L, D67N, K70R, T215Y V21I, V35T, V60I, K122P, I135V, S162A, K173T, Q174K, D177E, I178M, Q207E, R211KCRF02_AG
 MB_patCON02_CON701AJ577867AZT, DDINoneM41L, L210W, T215Y V35T, E36D, T39A, K43Q, I135V, S162A, K173A, Q174K, D177E, I195L, T200A, Q207E, R211KCRF02_AG
Non-B Workgroup (2005)PL1692558358AY901545DDINoneM41L, V75T, L210W, T215Y, K219KNY181CV35KT, T39A, V60VI, S68G, V118VI, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, K223Q, P243S, V245E, T286A, E291D, V292I, I293V, P294T, S322ACRF02_AG
 PL3768363158AY901685AZT, DDINoneM41L, D67N, T215Y V35KT, E36D, T39A, K43KE, V60VI, I135V, S162A, K173I, Q174K, D177E, T200A, E203D, Q207E, R211K, V245Q, K277R, T286A, E291D, V292I, I293V, P294A, S322TCRF02_AG
 PL3568567040AY901692ABC, AZT, 3TCNoneM41L, D67DN, M184V, T215F K20KR, V21I, V35T, V60I, K101Q, K122E, D123ST, I135R, S162A, K173T, Q174K, D177E, I178IM, T200A, Q207G, V245Q, E248D, T286TR, V292I, I293V, E297ACRF02_AG
 IL32IL32cAY901737AZT, DDINoneM41L, D67N, F77FL, L210W, T215YA98AGK43N, V60VI, V118VI, D123E, S162A, K173I, Q174KR, D177E, D185DA, T200A, E203EDKN, Q207D, R211K, V245QCRF02_AG
 PL2646078692 AZT, D4T, DDINoneM41L, D67N, K70KR, T215Y V21I, T27S, K32R, V35T, T39A, V60I, I135V, S162A, K173T, Q174R, D177E, T200A, Q207E, R211K, V245Q, T286A, E291D, V292I, I293V, P294A, S322T, I326VCRF02_AG
Seyler (2007)282CS_282 AZT, D4T, 3TC, DDINoneM41L, D67N, T69D, M184V, T215Y V8VM, V35T, E36ED, T39TK, K43KE, V60I, I135L, S162A, K173I, Q174K, I178L, G196E, T200A, Q207E, V245QCRF02_AG
Delgado (2008)GH_050GH_050EU177922AZT, 3TCNoneM41L, M184V V35T, T39A, D123E, I135V, S162A, K173A, Q174K, D177E, T200A, Q207G, R211K, V245Q, P247A, E248D, T286A, E291D, V292I, I293V, P294T, V317VA, S322TCRF02_AG
Holguin (2008)LP3801SP-LP38DQ926897AZT, 3TCNoneM41L, D67N, K70R, M184V V35T, E36D, V60I, K122E, D123S, I135V, S162A, K173A, Q174K, D177E, T200A, Q207ECRF02_AG
Rosen-Zvi (2008)104p1-2 AZT, 3TCNoneM41L, M184V, T215CY V35T, K43A, K49R, V60I, D121H, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245KQ, K281R, T286A, V292VI, I293V, P294TCRF02_AG
  05p1-3 AZT, 3TC, TDF, D4TNoneM41L, T215Y V35T, K43A, K49R, V60VI, D121H, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245K, K281R, T286A, I293V, P294T, E297K, S322T, I326VCRF02_AG
 4507p45-4 ABC, 3TC, AZT, TDFNoneM41L, M184V, T215F I5V, V35T, V90I, K104R, F124L, R125E, I135IT, S162Y, K173T, Q174R, D177E, T200A, Q207G, R211K, V245Q, E248N, V276I, L283I, T286A, A288T, E291D, V292I, I293V, P294T, S322GCRF02_AG