<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF02_AG
Gene RT
Mutation M184V
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 14
Patients 30
Isolates 31
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Si-Mohamed (2000)AS_FANAS_FANAF199276D4T, 3TCNoneM41L, D67N, M184V, T215Y V60I, V118I, K122E, I135V, T139K, S162A, K166E, E169K, K173T, Q174A, D177E, I178M, T200A, E203K, Q207E, H208Y, R211KCRF02_AG
Yahi (2001)NY_M32M32AY010448AZT, 3TCNoneK70KR, M184V V21I, V35T, T39A, K126KR, I135IV, I142V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, F214LCRF02_AG
 NY_M47M47AY010503D4T, 3TCNoneD67N, M184V, T215F, K219E V35T, E36D, E40D, K49R, V60I, K102Q, I135V, S162A, K173A, Q174K, D177E, I178M, T200A, Q207E, R211KCRF02_AG
Venturi (2002)GV-29GV-29.1AF517281AZT, 3TCNoneM41ML, M184V, T215FY V35IT, S68G, D123E, I135V, S156P, S162A, K173T, Q174NS, D177E, T200A, Q207ECRF02_AG
 GV-56GV-56.1AF517308AZT, 3TCNoneM184V S68G, I135V, S162A, K173T, Q174K, D177E, I178M, I195L, G196E, Q197K, T200A, Q207ECRF02_AG
Vergne (2003)VL98SN65HALD00SN65AJ583751D4T, DDI, AZT, 3TCNoneM184V V35T, E40D, K122E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, V245E, T286A, A288T, E291D, V292I, I293V, P294T, L295M, S322A, R356K, M357K, R358K, G359S, A371V, K374R, I375V, T377S, K390R, T403MCRF02_AG
 VL98SN34hald01SN34AJ583745AZT, 3TCNoneM184V V35T, E36D, E40D, K49R, I135V, S162A, K173A, Q174R, D177E, I178V, T200A, Q207E, V245K, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357R, G359A, V365I, T369A, E370A, A371V, I375V, A376S, K390R, K395R, T403M, E432DCRF02_AG
Montes (2004)MB_patFEU02_FEU726AJ577889AZT, DDI, 3TC, D4TNoneM184V K11T, E28A, K32R, V35T, E40D, V60I, V118I, D121H, K122E, D123S, I135T, K173S, Q174R, D177E, I178L, V179I, T200A, Q207A, F214LCRF02_AG
Delaunay (2005)DC_00202_1001w12DQ286503ABC, TDF, 3TCNoneM184V V35T, E36D, V60I, V90I, D121Y, K122E, D123G, T139K, I142V, S162Y, K173S, Q174K, D177E, V179I, T200A, Q207E, R211KCRF02_AG
Non-B Workgroup (2005)PL3568567040AY901692ABC, AZT, 3TCNoneM41L, D67DN, M184V, T215F K20KR, V21I, V35T, V60I, K101Q, K122E, D123ST, I135R, S162A, K173T, Q174K, D177E, I178IM, T200A, Q207G, V245Q, E248D, T286TR, V292I, I293V, E297ACRF02_AG
 PL4102370489AY901701AZT, 3TC, DDINoneM184V V21I, K32R, V35K, V60I, T69TA, V106I, S162A, K173T, Q174K, D177E, I178L, T200S, R211K, K238KR, V245Q, E248N, T286A, E291D, I293V, E297T, I326V, I329LCRF02_AG
 PL53161101108 3TC, D4TNoneM184V P4PT, T7TP, V35T, K122E, S162A, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, V245Q, T286A, E291D, V292I, I293V, P294T, V317A, S322TCRF02_AG
Weber (2005)01M612201M6122AY677602AZT, 3TCNoneK70R, M184V E6D, V35T, V60I, T69S, D121Y, K122E, K173A, Q174K, D177E, V179I, Q207A, R211S, F214L, V245T, P247T, D250E, A272P, K277R, L282C, T286A, I293V, E297ACRF02_AG
 M86254M86254AY714444AZT, 3TCNoneM184V K20KR, V35T, V60I, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, F214FL, P243T, V245Q, A272P, T286A, E291ED, V292I, I293V, S322T, I326VCRF02_AG
Laurent (2006)CK2-4702CM-47AM279442AZT, 3TCNoneM184V V35T, V90I, K122T, A158T, S162A, K173T, D177E, T200A, Q207D, V245K, K275R, V276I, T286A, E291D, V292I, I293V, P294V, S322A, D324E, G335D, R356K, M357R, R358K, G359S, I375V, T377Q, K390R, K395R, T403S, E432DCRF02_AG
 CK22-3103CM2-31AM279454D4T, 3TCNoneM184V K11Q, V35KN, K122E, D123G, S162A, K173T, Q174N, D177E, I178V, T200A, Q207D, R211K, V245Q, A272P, V276I, E291D, V292I, I293V, S322A, I326V, A327V, R356K, M357K, G359S, T369V, A371V, I375A, K390R, T403M, E432DCRF02_AG
 CK22-3303CM2-33AM279455AZT, 3TCNoneM184V V35T, K122E, I135V, S162A, K173V, Q174K, D177E, I178M, T200E, I202V, E203Q, Q207E, V245E, S251N, K277R, T286A, V292I, I293V, P294T, S322A, I326V, G335D, R356K, M357K, G359S, T369V, A371V, I375V, K390R, E396D, T403LCRF02_AG
Seyler (2007)004CS_004 AZT, 3TCNoneM184V V35T, T39KN, E40D, I135V, S162A, K173T, Q174E, D177E, T200A, Q207E, V245QCRF02_AG
 027CS_027 AZT, 3TCNoneM41ML, M184V, T215SY V21VI, V35T, E36D, T39A, E79EK, W88C, V118I, K122E, I135R, S162A, K173T, Q174K, D177E, T200A, E203K, Q207E, R211K, F214L, V245Q, Y271F, T286A, E291D, I293V, S322T, I326VCRF02_AG
 282CS_282 AZT, D4T, 3TC, DDINoneM41L, D67N, T69D, M184V, T215Y V8VM, V35T, E36ED, T39TK, K43KE, V60I, I135L, S162A, K173I, Q174K, I178L, G196E, T200A, Q207E, V245QCRF02_AG
 422CS_422 AZT, DDINoneM184V, T215YK103N, Y188F, M230LV35T, E36ED, T39A, K102R, V106I, D121H, K122E, D123DG, I135V, S162A, K173T, Q174K, D177E, G196E, T200A, Q207E, R211K, V245QCRF02_AG
 545CS_545 AZT, D4T, 3TC, DDINoneD67DN, K70KR, M184V V35T, E36D, K122E, S134SR, I135V, V148VG, S162A, K173T, Q174K, D177E, I178M, L193F, T200A, Q207E, R211K, V245QCRF02_AG
von Wyl (2007)1205327019EF449829NRTINoneM184V V35T, T39S, K102R, D121H, K122E, I135T, S162A, K173T, Q174R, D177E, I178M, G196R, T200A, Q207D, R211KCRF02_AG
 105697505EF449819NRTINoneM184V P4T, V35T, E36ED, K122E, I135V, S162A, K173T, Q174K, D177E, I178IM, T200AV, R211GCRF02_AG
 291845355EF449895NRTINoneM184V V35T, T39L, I135V, S162A, K173A, Q174K, D177E, I178M, T200A, Q207ECRF02_AG
 1121435894EF449908NRTINoneM184V P4S, V35T, E36D, T39S, E89G, V90G, Q91P, L92V, D121H, I132V, I135V, S162A, K173T, Q174K, D177E, V179I, T200A, E203K, Q207ECRF02_AG
Delgado (2008)GH_050GH_050EU177922AZT, 3TCNoneM41L, M184V V35T, T39A, D123E, I135V, S162A, K173A, Q174K, D177E, T200A, Q207G, R211K, V245Q, P247A, E248D, T286A, E291D, V292I, I293V, P294T, V317VA, S322TCRF02_AG
Holguin (2008)LP3801SP-LP38DQ926897AZT, 3TCNoneM41L, D67N, K70R, M184V V35T, E36D, V60I, K122E, D123S, I135V, S162A, K173A, Q174K, D177E, T200A, Q207ECRF02_AG
Rosen-Zvi (2008)104p1-2 AZT, 3TCNoneM41L, M184V, T215CY V35T, K43A, K49R, V60I, D121H, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245KQ, K281R, T286A, V292VI, I293V, P294TCRF02_AG
 4506p45-3 ABC, 3TC, AZTNoneM184V, T215TFIS I5V, V35T, V90VI, K104R, S162Y, K173T, Q174R, D177E, T200A, Q207G, R211K, V245Q, E248N, V276I, L283I, T286A, A288T, E291D, V292I, I293V, P294T, S322G, I326VCRF02_AG
  07p45-4 ABC, 3TC, AZT, TDFNoneM41L, M184V, T215F I5V, V35T, V90I, K104R, F124L, R125E, I135IT, S162Y, K173T, Q174R, D177E, T200A, Q207G, R211K, V245Q, E248N, V276I, L283I, T286A, A288T, E291D, V292I, I293V, P294T, S322GCRF02_AG