<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation L74I
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 1
Patients 7
Isolates 7
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TH_127TH_127AY605549AZT, 3TCNoneM41L, D67N, K70R, L74I, T215F, K219Q V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245K, D256ECRF01_AE
 TH_130TH_130AY605553AZT, 3TCNoneD67N, T69D, K70R, L74I, T215F, K219Q V35T, T39K, K43E, V60I, K122E, D123S, K173T, Q174K, D177E, I178M, Q207A, R211S, K238R, V245KCRF01_AE
 TH_150TH_150AY605564AZT, D4T, DDINoneD67N, K70R, L74I, T215F, K219Q P25A, V35T, T39K, K43E, K64H, T69N, V90I, D123N, R172K, K173I, Q174K, D177E, I178M, Q207A, R211S, D218E, V245KCRF01_AE
 TH_439TH_439AY901842D4T, DDINoneM41L, L74I, V75T, L210W, T215Y V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 TH_515TH_515AY901865D4T, DDINoneD67N, K70R, L74I, T215F, K219Q V35T, T39E, V60I, K122E, D123N, I135T, S162A, K173I, Q174K, D177E, I178M, G196E, Q207A, R211S, K238R, V245ECRF01_AE
 TH_645TH_645AY901909AZT, DDINoneD67N, L74I, T215F, K219QA98GV35T, T39K, K43E, T69N, K122E, D123S, K173I, Q174K, D177E, V179I, T200I, I202V, Q207A, R211S, K238RCRF01_AE
 TH_711TH_711 D4T, DDINoneM41L, D67N, L74I, V75T, L210W, T215Y K32I, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, G196E, T200I, Q207A, R211N, K238R, V245ECRF01_AE