<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation T69S
Rx RTI-naive
IncludeMixtures No
References 17
Patients 32
Isolates 32
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Lan (2003)NTHvr72NTHvr72AY238103NoneNone  E6D, K11T, K30KE, V35T, T39E, T69S, V106I, K122E, D123S, S162C, K173T, Q174KR, D177DE, I178M, E203D, Q207E, K238R, V245E, E248GCRF01_AE
Sirivichayakul (2008)NBC-16NBC-16RTJQ364400NoneNone  V35T, T39K, K43Q, T69S, K122E, D123S, K173I, Q174K, D177E, I178V, V179I, Q207A, R211S, K238R, V245E, S251RCRF01_AE
Auwanit (2009)140AE-RT140FJ463588NoneNone V179VDE6D, K11T, K20R, V35T, T39K, K43E, V60I, T69S, K122E, D123S, I142V, K173L, Q174K, D177E, T200IL, Q207A, R211S, V245ECRF01_AE
Ishizaki (2009)C11C11gFJ006956NoneNone  E6D, V35T, T39N, T69S, K122E, D123S, S162C, K173T, Q174K, D177E, Q207S, R211S, K238RCRF01_AE
 A2_211A2_211FJ007039NoneNone  E6D, V35T, T69S, K122E, D123S, S162C, K173I, Q174K, D177E, T200A, Q207S, R211T, K238R, V245E, K249RCRF01_AE
Vercauteren (2009)pt5039904009115GQ400521NoneNone  E6D, V35T, T39K, K43E, T69S, K122E, D123DGNS, S162C, K173R, Q174K, D177E, I178M, T200TA, K238R, V245E, K277R, T286TA, E291D, V292I, I293V, E312T, I326V, I329VCRF01_AE
Hattori (2010)A07-201056A07-201056AB863788NoneNone  E6D, V8I, K11T, V35T, T39KR, E40EQ, K43E, K46KQ, T69S, K102R, K122KE, D123NS, K173T, Q174K, D177E, V179I, G196GE, Q207A, R211K, V245E, A272ASCRF01_AE
 C07-51110576C07-51110576AB864983NoneNone  E6D, V8I, V35T, T39K, K43E, T69S, K102R, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238RCRF01_AE
Trinh (2012)VN-39VN-39GQ161892NoneNone  E6D, V35T, T39K, T69S, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207A, R211S, W212*, V245ECRF01_AE
Yang (2012)GZ163GZ163JN848881NoneNone V179EV35T, T39D, T69S, W88WG, T107S, K122E, D123S, I135R, S162C, K173AT, Q174K, D177E, Q207S, R211S, K238R, V245E, T286A, E291D, I293VCRF01_AE
Zeng (2012)CN1396CN1396JQ028272NoneNone  E6D, K11T, V35T, K43R, T69S, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200A, Q207K, R211S, K238R, V245E, A272P, K281R, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435A, N447S, V458I, D471E, Q480H, H483Q, L491S, I505V, K512R, E514D, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 CN1230CN1230JQ028349NoneNone  E6D, K22G, V35A, T39E, K65E, T69S, K122E, D123S, I135R, S162C, K173T, Q174K, D177E, G196E, Q207N, K238R, V245E, A272P, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435I, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, Q547K, A554TCRF01_AE
 CN1370CN1370JQ028369NoneNone  E6D, K11T, V35T, T39E, T69S, K122E, D123S, S162C, K173I, Q174K, D177E, Q207D, K238R, V245E, A272P, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, E514D, L517V, S519N, Q520K, Q524E, A534S, A554SCRF01_AE
Chen (2013)11YNHH11011YNHH110JX412359NoneNone  E6D, K11R, V35T, T69S, K122E, D123S, S162C, K173V, Q174K, D177E, Q207N, R211S, K238R, V245E, E248EK, A272P, T286A, V292I, I293VCRF01_AE
Frentz (2013)EHR-46864EHR-46864JX300323NoneNone  E6D, K11A, V35I, E36EG, T39E, S68G, T69S, D121DE, K122E, D123S, K166KR, K173IL, Q174K, D177E, I178M, T200M, Q207A, R211S, V245ECRF01_AE
Hawke (2013)2103286621032866KC238058NoneNone  K11T, K20R, V21I, V35T, T39E, E40D, T69S, K122E, D123N, K173S, D177E, V179I, T200A, I202V, Q207K, R211K, F214FL, V245Q, E248D, D250E, S251HCRF01_AE
Kiertiburanakul (2013)R73092R73092KC810631NoneNone  E6D, V35T, T39K, K43E, T69S, K122E, D123S, I135V, K166KR, K173I, Q174K, D177E, I178M, V179I, T200TA, Q207A, R211S, V245ECRF01_AE
 R12147R12147KC994281NoneNone  V35T, T69S, K122E, D123S, I135IV, S162C, K173IT, Q174K, D177E, I178M, V179I, T200I, Q207N, R211S, K238R, V245E, K281R, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A400TCRF01_AE
 R74175R74175KC791394NoneNone  E6D, K11T, I31PS, V35T, T39A, T69S, V111I, K122E, D123NS, I135T, T165TI, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 R74186R74186KC791405NoneNone V179DE6D, K11T, I31PS, V35T, T39K, V60I, T69S, V111I, K122E, D123DGNS, I135T, K173I, Q174K, D177E, T200A, Q207A, R211S, F214L, V245ECRF01_AE
 R72104R72104KC867641NoneNone  V35L, E36N, I37F, T39E, T69S, K102R, K122E, D123S, I142T, S163C, K173I, Q174K, N175Y, Q207A, R211S, K238R, V245ECRF01_AE
 R74086R74086KC791305NoneNone  E6D, K11T, V35T, T39K, K43E, T69S, K122E, D123S, S162SN, S163SC, K173I, Q174K, D177E, I178IM, T200TI, Q207A, R211S, K238R, V245ECRF01_AE
 R72023R72023KC867572NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39K, K43E, T69S, K122E, D123S, K173I, Q174K, I178V, T200A, Q207A, R211S, V245QCRF01_AE
 R41051R41051KC970937NoneNone  P4H, E6D, K11T, M16R, V35T, T39K, K43E, T69S, K102Q, K122E, D123S, E138A, S162C, Q174N, D177E, Q207A, R211S, F214I_S, K238R, V245ECRF01_AE
 R71043R71043KC921910NoneNone  V35T, T39K, K43E, T69S, K122E, D123S, K173I, Q174K, D177E, T200A, E204Q, Q207A, R211S, V245Q, S251HCRF01_AE
 R72137R72137KC857128NoneNoneA62V T39K, K43E, T69S, K102Q, K122E, D123N, I135T, S162A, K173I, Q174KR, D177E, I178M, G196GE, Q207A, R211S, V245ECRF01_AE
 R72256R72256KC857238NoneNone V179DT39K, K43E, T69S, V111I, K122E, D123NS, S162C, K173I, Q174K, T200A, Q207A, R211S, V245ECRF01_AE
 R72213R72213KC857195NoneNone V179DT39K, K43E, T69S, V111I, K122E, D123S, K173IL, Q174K, D177E, T200A, Q207A, R211S, V245ECRF01_AE
Kiptoo (2013)KTL018KTL018KC516994NoneNone  V35T, E40ED, V60I, T69S, K122E, K173L, Q174K, D177E, V179I, G196E, Q207A, R211S, V245E, D250E, T286A, E291D, V292VI, I293V, E312DCRF01_AE
Li (2013)20312031JQ302563NoneNone  E6D, K11A, V35T, T39K, K43E, T69S, V90I, K122E, D123S, K173IL, Q174K, D177E, T200I, Q207A, R211K, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, T403IM, E404ED, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554TCRF01_AE
Wu (2013)HSP38HSP38KC203271NoneNone  E6D, V35T, T39K, K43E, V60I, T69S, K122E, D123S, I135V, S162C, K173R, Q174K, I178M, Q207A, R211S, K238R, V245ECRF01_AE
Zeng (2013)cdh27cdh27KC352197NoneNone  E6D, K11T, V35T, T39K, K43E, S48T, T69S, D113N, K122E, D123N, S162C, K173R, Q174E, D177E, I178M, E204K, Q207A, R211S, K238RCRF01_AE