<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation T69S
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 3
Patients 7
Isolates 7
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Piyasujabul (2002)DP_THMZ67DP_THMZ67AF368829AZTNone  E6D, V35T, T39K, K43E, T69S, K122E, D123S, I135T, I142T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245K, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, R356K, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491T, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
Hsu (2005)BAA154770BAA154770AY870168D4T, DDI, AZT, 3TCNoneD67N, T215F E6D, V35T, T39K, K43E, T69S, V106VI, I135IT, S162SN, Q174D, D177E, I178V, V179I, T200I, I202V, E204K, Q207A, R211S, D218DE, V245E, K275KQ, T286A, A288T, E291ED, V292I, I293V, E312T, I329V, G335D, Y342F, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400TCRF01_AE
 BAA157680BAA157680AY870185D4T, DDINoneA62V, K70N, V75A, F77L, Y115F, F116Y, Q151M, M184VV179DEE6D, K11T, V35T, T39K, K43E, T69S, K73L, K102Q, D121H, K122E, D123S, K173I, Q174K, D177E, T200A, I202V, Q207A, R211N, L228R, V245E, A272P, L283I, E291D, V292I, I293V, E312T, D324DE, L325I, I329V, G335D, R356K, M357K, G359S, K366R, A371V, K395R, A400TCRF01_AE
Non-B Workgroup (2005)TH_425TH_425 DDC, AZTNoneK70R, K219Q V35T, T39K, K43E, T69S, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207A, R211S, F214L, L228R, K238R, V245E, K249RCRF01_AE
 TH_444TH_444AY9018443TC, D4TNoneT215Y V21I, V35T, T39K, K43E, T69S, V111I, K122E, D123S, S162C, I167V, K173I, Q174K, D177E, I178L, V179I, T200I, Q207A, R211T, K238R, V245ECRF01_AE
 TH_715TH_715 AZT, DDINone  V35T, T39K, K43E, T69S, K122E, D123S, K173I, Q174K, I178M, I202V, Q207A, R211S, V245ECRF01_AE
 TH_410TH_410 AZT, 3TCNoneM184V V35T, T39R, K43E, T69S, K122E, D123S, S162C, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, W239C, V245ECRF01_AE