<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation T69N
Rx RTI-naive
IncludeMixtures No
References 18
Patients 49
Isolates 49
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Zhong (2007)D002505CN_025EF199567NoneNone  E6D, K11T, K22R, V35T, T39K, K43E, T69N, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207A, R211S, D237G, K238R, V245E, T253ACRF01_AE
Bao (2008)YUN01-38YUN01-38AM886214NoneNone  E6D, V35T, T39K, K43A, V60I, S68G, T69N, K122E, D123S, I135T, K166R, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E, V276I, L283I, T286A, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, T397I, A400TCRF01_AE
 YUN01-15YUN01-15AM886191NoneNone  E6D, V35T, T39K, K43E, S68G, T69N, K102R, K103R, K122E, D123S, I135T, K173V, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, K238R, V245E, V276I, L283I, T286A, I293V, K311AT, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, T397I, A400T, E432DCRF01_AE
Auwanit (2009)97AE-RT97FJ463571NoneNone V179DE6D, K11T, V35T, T39K, K43E, T69N, V111I, K122E, D123N, I135T, I142V, S163ST, K173I, Q174K, D177E, I178M, Q207A, R211S, V245KCRF01_AE
Ayouba (2009)R27R27_RTGQ352191NoneNone  E6D, K11IT, V35T, T39E, S68G, T69N, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207A, R211S, V245ECRF01_AE
Hattori (2010)F06-5112035F06-5112035AB866671NoneNone V179DE6D, V35T, T39E, T69N, K122E, D123S, I135V, S162C, K173I, Q174K, D177E, I178M, T200A, Q207A, R211SCRF01_AE
 C08-2066430C08-2066430AB864139NoneNone  M16MK, V35T, T39K, K43E, T69N, K122E, D123S, R125K, S162A, K173I, Q174K, D177E, I178M, V179I, Q182H, T200A, Q207A, R211S, K238R, V245K, V276ICRF01_AE
Phan (2010)ND26ND26AB519461NoneNone  E6D, K11T, V35T, T69N, K122E, D123S, S162C, K173M, Q174K, D177E, I202V, Q207S, R211SCRF01_AE
 O906O906AB519477NoneNone  E6D, K11T, V35T, T39K, T69N, V106I, D121Y, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200A, Q207S, R211SCRF01_AE
 NB38NB38AB519546NoneNone  E6D, V35T, T39E, T69N, V106I, V118I, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, Q207S, R211SCRF01_AE
 AH07AH07AB519564NoneNone  E6D, K11T, V35T, T39E, T69N, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207S, R211SCRF01_AE
 AH15AH15AB519569NoneNone  E6D, K11T, V35T, T39E, T69N, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207S, R211SCRF01_AE
Bontell (2011)Pat04508.VL772HsHQ852871NoneNone Y181CE6D, K11T, E28K, K32E, V35T, T39RS, T69N, V111I, K122E, D123S, K173I, Q174K, D177E, T200A, Q207K, R211SCRF01_AE
 Pat04408.VL773HsHQ852872NoneNone  E6D, K11T, V35T, T39N, T69N, K122E, D123N, I135V, I142V, S162C, K173I, Q174K, D177E, T200A, Q207N, R211KCRF01_AE
 Pat03208.VL789UsHQ852884NoneNone  E6D, K11T, V35T, T39K, T69N, V106I, K122E, D123S, S162C, Q174R, D177E, I178M, Q182QH, T200A, E203D, Q207D, R211SCRF01_AE
 Pat01009.VL973UsHQ852906NoneNone  K11T, V35T, T39K, K43KQ, T69N, V106VI, K122E, D123S, S162C, K173I, Q174K, D177E, Q207S, R211SCRF01_AE
Lazaro (2011)TG-M3TG-M3HQ542767NoneNone  E6D, V35T, T39N, T69N, K122E, D123S, I142V, S162C, F171FY, K173IT, Q174K, D177E, I178M, T200A, Q207S, R211S, K238S, V245E, D256ECRF01_AE
Su (2011)LZ2151LZ2151HQ588225NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, T69N, K122E, D123N, I135T, K173I, Q174K, D177E, I178M, V179I, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 GXBY2058GXBY2058HQ588261NoneNone  E6D, K11T, V21I, V35T, T69N, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207N, R211S, K238R, V245E, K281R, L283ICRF01_AE
 GXBY7291GXBY7291HQ588272NoneNone  E6D, K11KT, V35T, T39K, K43E, V60I, T69N, K102Q, V111I, K122E, D123S, I142V, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, A272P, V276ICRF01_AE
Trinh (2012)VN-51VN-51HQ876638NoneNone  E6D, V35T, T39K, K43E, T69N, K122E, D123S, S162C, K173I, Q174K, D177E, Q207S, L210S, R211S, K238R, V245ECRF01_AE
 VN-104VN-104GQ161906NoneNone  E6D, V35T, T39E, T69N, K122E, D123S, I135T, S162C, G196R, Q207D, K238R, V245ECRF01_AE
 VN-37VN-37HQ876632NoneNone  E6D, V35T, T39A, T69N, K102E, K122E, D123S, S162C, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
Yang (2012)GZ015GZ015JN848848NoneNoneV75L E6D, P14PS, V35T, T39K, K43E, T69N, E79D, K122E, D123S, I135T, S162C, K173T, Q174K, D177E, Q207A, R211S, K238R, V245E, K275R, T286A, E291D, V292I, I293IVCRF01_AE
 GZ046GZ046JN848853NoneNone  E6D, K22KR, V35T, T39K, K43E, V60I, T69N, K122E, D123S, K173T, Q174K, D177E, I178M, V179I, T200I, Q207A, R211K, K238R, V245E, T286A, E291D, V292I, I293V, P294QCRF01_AE
Zeng (2012)CN1341CN1341JQ028265NoneNone  E6D, V35T, T39K, K43E, T69N, V106I, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200TA, Q207N, R211S, K238R, V245E, E248D, A272P, T286A, E291D, V292I, I293V, E312T, D324E, I326V, I329V, G335D, M357K, G359S, K366R, A371V, S379G, A400T, E432D, N447S, D471E, T477S, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, E529D, A534S, A554SCRF01_AE
 CN1389CN1389JQ028269NoneNone  E6D, V35T, T39N, T69N, K122E, D123N, S162C, K173I, Q174K, D177E, I202V, Q207K, R211S, K238R, V245E, V276I, L283I, T286A, I293V, E312T, D324E, I326V, I329V, G335D, Y342F, M357K, R358G, G359S, K366R, A371V, T377K, V381I, K390R, K395R, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554SCRF01_AE
 CN0333CN0333JQ028330NoneNone  E6D, K11T, V35T, T39K, K43E, T69N, K122E, D123S, S162C, Q174R, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E297V, E312T, V317T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T377M, K390R, A400T, T403M, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
Chow (2013)10MYKJ09910MYKJ099KC478016NoneNone  V35I, S68G, T69N, K122E, K173I, Q174K, T200A, Q207A, R211K, K238R, V245Q, A272P, K275R, K277T, E291N, V292I, I293VCRF01_AE
Kiertiburanakul (2013)R73162R73162KC810690NoneNone K103KNK30KE, I31IT, V35T, T39K, K43E, T69N, K122E, D123S, I135T, L149LGRV, S162C, K173KR, Q174K, D177E, D185DE, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 R72079R72079KC867619NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39R, K43E, V60I, S68G, T69N, K122E, D123S, K173R, Q174K, D177E, I178M, G196E, Q207A, R211S, V245ECRF01_AE
 R72080R72080KC867620NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39K, K43E, T69N, K102QR, G112A, K122E, D123N, I135L, S162C, T165I, R172K, K173I, Q174K, D177E, V179I, T200I, Q207A, R211S, V245ECRF01_AE
 R41002R41002KC970986NoneNone V179DE6D, K11T, V35T, T39K, S68G, T69N, V111I, K122E, D123N, K166R, K173I, Q174K, D177E, T200A, Q207A, R211S, V245ECRF01_AE
 R71TS261R71TS261KC921730NoneNone  V35T, T39K, K43E, S68G, T69N, W88S, K122E, D123S, I135T, K173I, Q174K, D177E, I178L, Q207A, R211S, K238R, V245ECRF01_AE
 R12111R12111KC994251NoneNone  E6D, V35T, T39K, K43E, K49R, T69N, V106I, K122E, D123NS, S162C, K173I, Q174K, D177E, G196GE, I202V, Q207A, R211S, K238R, V245E, V276I, I293V, E312I, I329V, G335D, M357K, G359S, K366R, A371V, I375V, K390KR, K395R, A400TCRF01_AE
 R41063R41063KC970999NoneNone V179DE6D, K11T, V35T, T39K, S68G, T69N, V111I, K122E, D123N, K166R, K173I, Q174K, D177E, T200A, Q207A, R211S, V245ECRF01_AE
 R74017R74017KC791237NoneNone  E6D, V8VI, V35T, T39K, K43Q, V60I, S68G, T69N, K122E, D123N, I135T, K173I, Q174K, D177E, I178M, V179I, G196GE, T200IMR, Q207A, R211S, K238R, V245ECRF01_AE
 R74034R74034KC791254NoneNone V179DE6D, K11KT, V35IT, E36ED, T39K, K43E, S68G, T69N, K122E, D123S, S163ST, K173I, Q174K, E204Q, Q207A, R211S, V245ECRF01_AE
 R73147R73147KC810680NoneNone  E6ED, K11ST, V35T, T39E, V60I, S68G, T69N, K122E, D123N, I135T, I142V, K173T, Q174K, D177E, I178M, G196GE, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 X12TS010X12TS010KC994406NoneNone  E6D, K22R, V35T, T39K, K43E, S68G, T69N, W88C, K122KE, D123NS, I135T, T165I, F171Y, K173S, Q174K, D177E, I202V, Q207A, R211S, K238R, V245E, K275KR, K277R, T286A, E291D, V292I, I293V, E312T, V317A, I326IV, I329VCRF01_AE
 R73174R73174KC810702NoneNone  I5V, E6D, V35T, T39K, K43E, S68G, T69N, V118VI, K122E, D123S, S162C, K173IV, Q174K, D177E, Q207A, R211S, V245ECRF01_AE
 R41110R41110KC971006NoneNone Y181CE6D, K11T, V35T, T39K, K43E, T69N, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 R73008R73008KC810810NoneNone  V35T, T39K, K43E, T69N, K122E, I135V, K173L, Q174K, D177E, I178V, T200A, I202V, Q207A, R211S, K238R, I244V, V245ECRF01_AE
 R72042R72042KC857106NoneNone  T39K, K43E, T69N, V106I, K122E, D123S, S162C, K173I, Q174K, D177E, T200A, I202V, Q207A, R211S, K238R, V245ECRF01_AE
 R72043R72043KC857107NoneNone  V60I, T69N, K122E, D123T, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
Li (2013)22162216JQ302684NoneNone  E6D, K11T, V35T, T39E, I50IT, T69N, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200TA, Q207S, R211S, V245E, A272AS, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I375V, A400T, T403M, E432D, N447S, D460N, D471E, Q480H, H483Y, L491S, S515L, L517V, S519N, Q524E, A534S, A554SCRF01_AE
Wu (2013)XCP49XCP49KC203275NoneNone Y181CE6D, K11T, V35T, T39K, T69N, V111I, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, V245ECRF01_AE
Zeng (2013)cdh44cdh44KC352214NoneNone Y181CP4Q, E6D, K11T, E28A, V35T, E36D, T39K, K43E, T69N, D113N, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, K238RCRF01_AE
Chung (2014)KGK41_RT_200eKGK41_RT_200eKF544231NoneNone  K11T, V35T, V60I, T69N, K122E, D123DG, I135T, I142IV, K173L, Q174K, D177E, V179I, Q207A, R211SCRF01_AE