<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation T69N
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 4
Patients 11
Isolates 12
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Ariyoshi (2003)JPN44JPN44A AZT, 3TC, D4T, DDINone  E6D, T7TI, V8I, V35T, T39K, K43E, T69N, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
 JPN12JPN12A AZT, DDI, 3TC, D4TNoneM41L, D67N, K70R, V75VIM, M184V, T215FV, K219Q E6D, K11T, K20R, V35T, T39K, K43E, V60I, K64KHNQ, T69N, D121H, K122E, D123S, I135IT, I167IV, K173I, Q174K, D177E, T200I, Q207A, R211S, F214FL, D218DE, L228LH, K238R, V245ECRF01_AE
  JPN12BAY901413AZT, DDI, 3TC, D4TNoneM41L, D67N, K70R, V75M, M184V, T215F, K219Q K20R, V35T, T39K, K43E, V60I, K64H, T69N, D121H, K122E, D123S, S162SDGN, I167V, K173I, Q174K, D177E, T200I, Q207A, R211S, D218E, L228H, K238RCRF01_AE
 JPN21JPN21BAY901423DDC, 3TC, D4TNoneM184V E6N, I31IT, V35T, T39K, K43E, S68G, T69N, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, V245KCRF01_AE
Non-B Workgroup (2005)TH_150TH_150AY605564AZT, D4T, DDINoneD67N, K70R, L74I, T215F, K219Q P25A, V35T, T39K, K43E, K64H, T69N, V90I, D123N, R172K, K173I, Q174K, D177E, I178M, Q207A, R211S, D218E, V245KCRF01_AE
 TH_170TH_170AY6055843TC, D4TNoneM41L, D67N, K70R, M184I, T215F, K219Q G18W, P19T, L34I, V35T, T39K, K43E, V60I, T69N, K122E, D123N, S162A, K173I, Q174K, D177E, E203K, Q207A, R211S, K223E, K238R, V245ECRF01_AE
 TH_213TH_213AY605616AZT, DDINoneD67N, K70R, T215F, K219Q V35T, T39K, K43E, T69N, K122E, D123S, I159L, K173I, Q174K, D177E, V179I, G196E, T200A, Q207A, R211S, K238RCRF01_AE
 TH_430TH_430AY901839AZT, DDINoneD67N, K70R, T215F, K219Q K20R, V35T, T39K, K43E, V60I, T69N, K122E, D123S, Y127D, K173I, Q174K, D177G, Q207A, R211S, K238R, V245ECRF01_AE
 TH_645TH_645AY901909AZT, DDINoneD67N, L74I, T215F, K219QA98GV35T, T39K, K43E, T69N, K122E, D123S, K173I, Q174K, D177E, V179I, T200I, I202V, Q207A, R211S, K238RCRF01_AE
 TH_707TH_707 AZT, DDINoneD67N, K70R, M184V, K219Q V35T, T39K, K43E, T69N, D121H, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
Ferradini (2011)40739RTHM026345TDF, 3TCNoneK65R, K70~, V75M, K219RK103N, Y181CV35T, T39D, S68N, T69N, K122E, D123S, I135T, K173L, Q174K, D177E, T200A, Q207S, R211S, L228R, K238RCRF01_AE
Khairunisa (2014)TD10TD10KM212836TDF, AZT, 3TCNoneM41L, L74V, M184V, L210W, T215YK101E, V108I, Y181C, G190A, M230LE6D, K11T, V35T, T39N, K43Q, T69N, V118I, K122E, D123S, I135V, E138Q, S162C, R172K, K173I, Q174K, D177E, I178M, Q207A, R211S, H221Y, K223R, V245ECRF01_AE