<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation S68G
Rx RTI-naive
IncludeMixtures No
References 54
Patients 198
Isolates 204
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Cornelissen (1997)92TH02092TH020AF009390NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, V90I, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238X, V245E, E291D, V292I, I293VCRF01_AE
Sirivichayakul (2001)SS045123045123AF191192NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, I135V, I142L, K173I, Q174K, D177E, T200I, Q207A, R211G, V245E, R284K, T286A, E291D, V292I, I293V, P294S, E312TCRF01_AE
Sutthent (2002)DP_THMZ13DP_THMZ13AF368817NoneNone  V8M, K11T, V35T, T39K, K43E, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, R307K, E312A, I326V, I329V, G335D, M357K, G359S, K366R, E370D, A371V, K390R, K395R, A400T, I411T, E432D, D471E, Q480H, Q487K, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
Lan (2003)NTHvr130NTHvr130AY238041NoneNone  E6D, K11T, V35T, T39E, S68G, K122E, D123S, K173I, Q174K, D177E, T200I, Q207G, K238R, V245ECRF01_AE
 NTHvr181NTHvr181AY238110NoneNone  V35T, T39K, E44K, S68G, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, E204K, Q207A, R211S, K238R, V245ECRF01_AE
 NTHvr30NTHvr30AY237977NoneNone  V35T, T39K, S68G, K122E, D123S, I135L, S162C, R172K, K173I, Q174K, D177E, T200I, Q207A, R211S, V245ECRF01_AE
 NTHvr40NTHvr40AY237996NoneNone  K11T, V35T, T39K, K49KR, S68G, K122E, D123S, I135T, Q174E, D177E, I195L, Q207A, R211S, K238R, V245ECRF01_AE
 NTHvr73NTHvr73AY238128NoneNone  V8A, K11T, E28G, K30E, I31IT, V35T, T39K, V60I, S68G, K122E, D123S, S162C, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 NTHvr74NTHvr74AY238104NoneNone  V35T, T39K, I50M, S68G, V106VI, K122E, D123S, S162C, T165TI, K173T, Q174K, D177E, I178M, I180IF, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 NTHvr76NTHvr76AY238111NoneNone  V35T, T39K, S68G, D123N, S162C, K173I, Q174K, D177E, I178M, Q207A, R211S, K238RCRF01_AE
Maljkovic (2003)MI_Pat9299SE17711AY165218NoneNone  E6D, K11T, V35T, E36D, T39K, K43E, S68G, K122E, D123S, K173I, Q174K, D177E, I178IM, V189I, Q207A, R211S, K238R, V245E, A272P, E291D, V292I, I293V, P294S, E297A, E312TCRF01_AE
Tovanabutra (2004)01THOUR414I01_414IAY358050NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135L, S162H, K173R, Q174K, D177E, I178M, Q207A, R211S, V245E, T286A, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, T403M, E432D, N447S, E449K, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, V531I, A534S, A554SCRF01_AE
Arien (2005)VI2621VI2621DQ177215NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, I293V, E312T, V317TCRF01_AE
Hsu (2005)LYH_AY870196BAA161380AY870196NoneNone  E6D, V35T, T39K, K43E, V60I, S68G, K122E, D123NS, I135T, T165I, K173I, Q174K, D177E, I178L, T200A, Q207A, R211S, V245E, V276VI, V292I, I293V, E312T, I329V, G335D, K350R, M357K, G359S, K366R, A371V, A376V, K390R, K395RCRF01_AE
 LYH_AY870203BAA161388AY870203NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, I135K, K173I, Q174K, D177E, Q207A, R211S, I244V, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376VCRF01_AE
 LYH_AY870204BAA161389AY870204NoneNone  E6D, V35T, T39K, K43E, S68G, V90VI, K122E, D123S, K173T, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395RCRF01_AE
 LYH_AY870208BAA161394AY870208NoneNoneV75VL P4PHSY, E6D, K11T, V35T, T39K, K43E, S68G, D121H, K122D, D123S, S162C, K173I, Q174K, D177E, T200TI, Q207A, R211S, K238R, V245E, V276VI, T286TA, V292I, I293V, P294PQ, K311R, E312N, I326V, I329V, G335D, R356K, M357K, G359S, K366R, A371V, I375IVCRF01_AE
 LYH_AY870210BAA161397AY870210NoneNone  E6D, V35T, T39K, K43E, S68G, K122E, D123S, K173T, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395RCRF01_AE
 LYH_AY870217BAA161405AY870217NoneNone  E6D, K11T, V35T, T39K, K43KE, K49KR, V60I, S68G, K122E, D123NS, I135L, E138G, K166KR, R172RK, K173I, Q174K, D177E, I178IM, V179VI, T200I, Q207D, R211RK, V245E, D250T, E291D, V292I, I293V, E312T, I326V, I329V, M357K, R358RT, G359S, K366R, A371V, K390RCRF01_AE
 LYH_AY870223BAA161413AY870223NoneNone  E6D, V35T, T39K, K43E, S68G, K122E, D123S, I135T, K173M, Q174K, D177E, I178L, T200A, Q207A, L210M, R211S, V245E, V276I, T286A, V292I, I293V, E312T, I326V, I329V, G335D, K350R, M357K, G359S, K366R, A371V, A376V, K390R, K395RCRF01_AE
Ly (2005)NL_KHM_CA47KHM_CA47DQ013409NoneNone  E6D, K11T, V35T, T39E, S68G, K122E, D123S, I135T, T165I, K173R, Q174KR, D177E, I178M, V179I, G196E, T200I, I202V, Q207A, V245ECRF01_AE
 NL_KHM_CA54KHM_CA54DQ013416NoneNone  E6D, K11T, V35T, T39E, S68G, K122E, D123N, I135R, K173A, Q174K, D177E, I178M, Q207A, R211S, V245ECRF01_AE
 NL_KHM_CD20KHM_CD20DQ013445NoneNone  E6D, K11T, V35T, T39E, S68G, K122E, D123S, K173I, Q174K, D177E, I178V, Q207A, R211S, K238R, V245ECRF01_AE
 NL_KHM_HM21KHM_HM21DQ013467NoneNone  E6D, K11T, V35T, T39K, S68G, K122E, D123S, S162N, K173L, Q174K, D177E, I178M, G196E, T200A, Q207T, R211S, V245E, K249RCRF01_AE
 NL_KHM_HM28KHM_HM28DQ013474NoneNone  E6D, K11T, V35T, T39G, S68G, K122E, D123S, T165I, K173I, Q174K, I178M, Q207S, R211SCRF01_AE
 NL_KHM_HM34KHM_HM34DQ013480NoneNone  E6D, V8I, K11T, V35T, T39E, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, L210I, R211S, K238R, V245ECRF01_AE
 NL_KHM_POP7KHM_POP7DQ013489NoneNone  E6D, K11T, V35T, T39E, S68G, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, T200A, Q207S, R211S, K238R, V245ECRF01_AE
 NL_KHM_SOS17KHM_SOS17DQ013507NoneNone  V35T, T39K, K43E, V60I, S68G, K122E, D123S, K173R, Q174K, D177E, I178M, Q207A, R211S, V245ECRF01_AE
Tee (2005)03MYKL146703_1467AY904644NoneNone  V35T, T39K, K43E, S68G, K122Q, D123S, K173A, Q174K, D177E, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 04MYKL179904_1799AY904691NoneNone  V35T, T39K, K43E, S68G, K122E, D123S, I135T, T139A, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 04MYKL161204_1612AY904665NoneNone  V21G, T27P, V35T, T39K, K43E, S68G, D121H, K122E, I135T, I142V, K166R, K173I, Q174K, D177E, I178V, T200I, I202V, Q207A, R211S, V245ECRF01_AE
 03MYKL151103_1511AY904649NoneNone  V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 03MYKL133603_1336AY904621NoneNone  V35I, T39K, K43E, S68G, K122E, D123S, S162A, K173R, Q174K, D177E, I178M, R206S, Q207K, R211S, V245ECRF01_AE
 03MYKL148003_1480AY904647NoneNone  V35T, T39K, K43E, V60I, S68G, K122E, D123N, K173I, Q174K, V179I, Q197E, Q207A, R211S, V245ECRF01_AE
Babic (2006)DB_SI3493-03SI3493-03AJ971102NoneNone V179DI5V, E6D, K11T, K20R, V35T, T39K, K43EQ, V60I, S68G, V111I, K122E, D123N, S163T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, L282C, T286A, E291D, V292I, I293V, P294Q, E312T, V314A, S322L, I329V, K331NCRF01_AE
Jayaraman (2006)1-00-00981-00-0098 NoneNone  E6D, V8I, K11T, K20R, V35T, T39K, K43E, S68G, K122E, D123N, I135T, T165I, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, V245ECRF01_AE
Watanaveeradej (2006)99TH_C108099_C1080AY945712NoneNone  E6D, K11S, V35T, T39K, K43E, V60I, S68G, K122E, D123N, I135T, T165I, K173I, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, K259R, I274V, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, L452I, T470S, D471E, Q480H, L491S, K512R, L517V, Q524E, A534S, A554SCRF01_AE
 01TH_C325601_C3256AY945720NoneNone  E6D, V8I, K11T, V35T, T39K, K43E, S68G, K122E, D123S, I135T, K166R, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312I, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, T397I, A400T, T403M, E432D, V435I, D460N, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
Gatanaga (2007)C03-51110049-1C03-51110049-1AB640149NoneNoneV75VL E6D, V35T, T39K, K43E, S68G, D123S, K173I, Q174K, D177E, Q207A, R211S, K238RCRF01_AE
 C03-51110054-1C03-51110054-1AB640154NoneNone V179EV35T, T39K, V60I, S68G, K122E, D123S, I135R, K173I, Q174K, D177E, T200I, Q207A, R211S, K238RCRF01_AE
 C04-51110192-1C04-51110192-1AB640292NoneNone  E6D, I31T, V35T, T39K, K43E, S68G, K122E, D123N, K173I, Q174K, D177G, T200A, Q207A, R211S, K238RCRF01_AE
 C03-5555-5472-1C03-5555-5472-1AB640382NoneNone  E6D, K11T, V35T, E36ED, T39KR, K43E, V60I, S68G, K122E, D123S, I135T, K173IT, Q174K, D177E, I178M, T200TA, Q207A, R211S, K238KR, V245ECRF01_AE
 C03-5555-5546-1C03-5555-5546-1AB640386NoneNone  E6D, K11KT, V35T, T39K, K43E, K66KR, S68G, K101Q, V106VI, K122E, D123NS, I135R, K173IT, Q174K, D177E, I178M, Q207A, L210LM, R211S, K238R, V245ECRF01_AE
 C04-5555-5973-1C04-5555-5973-1AB640409NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, I135T, K173N, Q174K, D177E, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 C04-5555-6196-1C04-5555-6196-1AB640439NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, K166KR, K173I, Q174K, D177E, T200TAIV, Q207AT, R211S, V245ECRF01_AE
 C03-2066173-1C03-2066173-1AB640470NoneNone  K11A, V35T, T39K, K43E, V60I, S68G, N81NI, K122E, D123S, K173M, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 C04-2066216-1C04-2066216-1AB640487NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, W71WG, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, T200A, Q207D, R211K, K238R, V245E, K249R, L260ICRF01_AE
Han (2007)LN6104CNLN61EF122534NoneNone  E6D, K11T, V35I, T39K, S68G, K122E, D123S, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, T286ACRF01_AE
 LN7804CNLN78EF122543NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E, T286ACRF01_AE
Liu (2007)fj50fj50EF432683NoneNone  E6D, K11A, V35T, E36A, T39K, K43E, S68G, K122E, D123N, I135T, K173I, Q174K, D177ECRF01_AE
 fj61fj61EF432691NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, D121H, K122E, D123S, T165I, K173I, Q174K, D177E, G196ECRF01_AE
Chang (2008)TW10433TW10433DQ646516NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, V106G, V111G, D113A, S117P, D121Y, K122E, D123E, I135T, K173A, Q174K, D177E, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 TW0338aTW0338a NoneNone  E6D, V8I, K11T, V35T, T39K, K43KE, V60I, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, V245LQCRF01_AE
 TW9241aTW9241a NoneNone  E6D, V8VI, K11KT, V35I, T39K, K43E, S68G, V90VI, K122E, D123S, I135IT, K166KR, K173I, Q174K, D177E, I178M, V179I, G196A, I202IV, E203D, Q207A, R211S, V245ECRF01_AE
 TW5297aTW5297a NoneNone  E6D, K11T, K20X, K22R, V35T, T39K, K43E, K49R, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
 TW7513aTW7513a NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122Q, D123N, K166R, K173I, Q174K, D177E, V179I, T200A, Q207E, K238R, V245EQCRF01_AE
 TW7583aTW7583a NoneNone  E6D, K11T, K22R, W24X, A33X, V35T, T39K, K43E, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
 TW10522aTW10522a NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, D121Y, K122E, D123E, I135T, K173A, Q174K, D177E, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 TW10541aTW10541a NoneNone  E6D, K11T, K22R, V35T, T39K, K43E, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
 TW4530aTW4530a NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, D121Y, K122E, D123E, I135T, K173A, Q174K, D177E, V245QCRF01_AE
Ibe (2008)159159AB356207NoneNoneV75VL E6D, K11T, T27S, V35T, T39K, K43E, V60I, S68G, K122E, D123S, S162A, K173I, Q174K, D177E, T200A, Q207A, R211SCRF01_AE
 228228AB356257NoneNone  E6D, K11T, P19PL, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178IMV, Q207A, R211SCRF01_AE
 425425AB356396NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, D121H, K122E, D123S, I135T, K173IT, Q174K, D177E, I178IM, T200TA, Q207A, R211SCRF01_AE
Sirivichayakul (2008)BED-9BED-9RTJQ364355NoneNone  V35T, T39K, K43E, S68G, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, H221QCRF01_AE
 BED-11BED-11RTJQ364357NoneNone  V35T, T39K, K43E, V60I, S68G, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, V245ECRF01_AE
 BED-26BED-26RTJQ364367NoneNone  V35T, T39K, K43E, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
 BED-33BED-33RTJQ364372NoneNone  E42K, V60I, S68G, K122E, D123N, I135T, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, V245ECRF01_AE
 NBC-29NBC-29RTJQ364413NoneNone  V35T, T39K, K43E, S68G, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 NBC-37NBC-37RTJQ364421NoneNone  V35T, T39K, K43E, S68G, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, P236H, K238R, Q242R, V245ECRF01_AE
Aghokeng (2009)CYR20CYR20GU191552NoneNone  K11E, V35T, T39R, S68G, D121Y, K122E, D123G, K173A, Q174K, D177E, G196E, T200I, Q207A, R211S, V245E, T286A, I293V, E312D, I329V, G335D, M357K, G359S, K366R, T369A, A371V, A376S, S379G, K390R, T403MCRF01_AE
Auwanit (2009)164AE-RT164FJ463596NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, D86G, V111I, K122E, D123S, I135R, K173I, Q174K, D177E, I178L, Q207A, R211S, I244V, V245ECRF01_AE
Ayouba (2009)FD0487FD0487RTGQ352006NoneNone  V35T, V60I, S68G, K102R, K122E, D123S, K173I, Q174K, D177E, T200I, Q207K, R211S, K238KR, V245ECRF01_AE
 FD0704FD0704RTGQ352039NoneNone  V35T, T39K, K43E, S68G, K102KR, D121H, K122E, D123S, K173I, Q174K, I178L, T200I, Q207AT, R211S, K238R, V245ECRF01_AE
 FD0731FD0731RTGQ352042NoneNone  V35T, T39K, K43E, S68G, V106I, K122E, D123N, K166R, K173I, Q174K, D177E, I178M, T200TA, Q207A, R211S, K238R, V245ECRF01_AE
 R15R15_RTGQ352182NoneNone  E6D, K11T, V35T, T39E, S68G, D123G, I135T, K173R, Q174K, D177E, T200A, Q207E, R211N, K238R, V245ECRF01_AE
 R58R58_RTGQ352219NoneNone  V35T, T39K, K43E, S68G, K122E, D123S, T139TA, S162CG, K173T, Q174K, D177E, I195L, Q207A, R211S, K238R, V245ECRF01_AE
 R70R70_RTGQ352227NoneNone  V35T, T39K, S68G, K122E, D123S, I135T, I142IV, S162C, K173M, Q174K, D177E, E194Q, I195L, Q207A, R211S, K238R, V245ECRF01_AE
Ishizaki (2009)A2_178A2_178FJ007027NoneNone  E6D, K11T, V35T, T39K, S68G, K122E, D123S, S162C, K173I, Q174K, D177E, Q207S, R211S, K238R, V245ECRF01_AE
 A457A457FJ007333NoneNone  E6D, K11T, V35T, T39K, S68G, D123N, T165I, K173I, Q174K, D177E, V179I, Q207S, R211S, K238R, V245ECRF01_AE
Lee (2009)S07026S07026EU715185NoneNone  E6D, V35I, T39D, S68G, K104R, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E297K, A304E, E312T, I326V, I329VCRF01_AE
 S07037S07037EU715188NoneNone  E6D, V8I, K11T, V35T, T39K, K43E, S68G, K122E, D123N, K173T, Q174K, D177E, T200I, Q207A, R211S, V245E, V276VI, T286TA, E291D, V292I, I293V, E312T, I326V, I329VCRF01_AE
 S07042S07042EU715193NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, W88C, K122E, D123S, E138A, K173I, Q174K, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, K275R, T286A, E291D, V292I, I293V, E312T, I326V, I329VCRF01_AE
 S07008S07008EU715196NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211N, K238R, V245E, E291D, V292I, I293V, L303W, E312T, I326V, I329VCRF01_AE
 S07046S07046EU715219NoneNone  E6D, V35T, T39K, K43E, S68G, K102R, K122E, D123S, K173T, Q174K, D177E, I178L, T200M, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329VCRF01_AE
 S07060S07060EU715234NoneNone  E6D, V35T, T39K, K43E, S68G, K122E, D123S, I135T, K173T, Q174K, D177E, T200TI, Q207A, R211RS, K238R, V245D, V276I, T286A, E291D, V292I, I293V, K311KR, E312PT, I326V, I329V, K331N, Q334RCRF01_AE
Liao (2009)VNND1598VNND15FJ185235NoneNone  E6D, K11T, V35T, T39K, S68G, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238R, V245E, K249R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 VNHCM30997VNHCM309FJ185260NoneNone  E6D, K11T, I31V, V35T, T39N, S68G, H96R, K122E, D123S, T165I, K173I, Q174K, D177E, I178M, T200A, Q207A, R211N, V245E, K277R, T286A, A288G, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534SCRF01_AE
Nouhin (2009)KC32KC32RTFJ531904NoneNone  T39K, S68G, K122E, D123S, I135IV, I159IV, S163ST, K173R, Q174K, D177E, I178M, Q207A, R211SCRF01_AE
 KC40KC40RTFJ531912NoneNone  T39K, K43Q, S68G, K122E, D123S, S162H, K166R, K173I, Q174K, D177E, Q207A, R211S, K238RCRF01_AE
 KC47KC47RTFJ531919NoneNone  T39K, K43E, V60I, S68G, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, Q207A, R211SCRF01_AE
 KC50KC50RTFJ531922NoneNone  T39K, K43E, S68G, K102R, K122E, D123S, S162N, K173I, Q174K, D177E, I178IM, T200I, Q207A, R211SCRF01_AE
 KC63KC63RTFJ531935NoneNone  T39K, K43E, S68G, K122E, D123S, I135T, T165I, K173R, Q174K, D177E, I178M, Q207A, R211SCRF01_AE
Tu (2009)7plasma7EU518305NoneNone  E6D, K11T, V35T, T39KN, K43E, S68G, K122E, D123N, K166R, K173I, Q174K, N175H, D177E, I178M, T200V, Q207A, R211SCRF01_AE
 37plasma37EU518328NoneNone  E6D, K11S, V35T, T39K, K43E, S68G, K102R, K122E, D123N, I135T, K173I, Q174K, D177E, I178M, T200A, Q207A, R211SCRF01_AE
Vercauteren (2009)pt15863841341890GQ399438NoneNone  E6D, K11T, T27S, V35T, T39K, K43E, V60I, S68G, K122E, D123S, T165TI, K173R, Q174K, I178IM, Q207E, R211S, K238R, V245E, T286A, E291D, V292I, I293V, T296S, E312T, I326V, I329VCRF01_AE
 pt14174760279859GQ399607NoneNone  E6D, V8VI, K11T, V35T, T39K, K43E, V60I, S68G, K103M, D121H, K122E, D123S, K173Q, Q174K, D177E, D192E, T200A, Q207A, R211S, V245E, A272P, V276I, T286A, E291D, V292I, I293V, E298EK, L310I, E312TCRF01_AE
 pt10017209704423GQ400023NoneNone V179EE6D, V35T, T39K, K43E, V60I, S68G, V106VI, K122E, D123S, I135R, S163T, T165I, K173I, Q174K, D177EG, Q207A, R211S, K238R, V245E, V276I, L283LI, T286A, E291D, V292I, I293V, E312T, H315L, I329VCRF01_AE
 pt323JULc9Y2qzkGQ400701NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123N, I135T, T165I, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E, K277R, T286A, E291D, V292I, I293V, E297EKCRF01_AE
 pt285lPONbZRtMkGQ400739NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, I135T, T165I, K173I, Q174K, D177E, I178M, T200A, E204EK, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293VCRF01_AE
 pt262MtEEcRdta4GQ400762NoneNone  E6D, V10VL, K11T, G15GE, M16ML, G18GV, V35T, T39K, K43E, V60I, S68G, K122E, D123N, I135T, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, E297EKCRF01_AE
 pt191PVUfYROa4vGQ400833NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123N, I142IT, S162SAGT, T165TI, K173I, Q174K, D177E, I178M, Q207A, R211S, V245ECRF01_AE
 pt97uzTZcDw0JoGQ400927NoneNone  E6D, V35T, T39K, K43E, V60I, S68G, V118I, K122E, D123S, I135T, K166R, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293VCRF01_AE
Bonura (2010)1193_881193_88GU969548NoneNone  E6D, K11T, V35T, T39K, E40D, K43E, S68G, D121H, K122DE, D123GS, I135T, T139A, K173I, Q174K, D177E, I178M, Q207A, R211S, V245D, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329VCRF01_AE
Chin (2010)C187C187GQ290724NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, I135T, S162C, K173R, Q174K, D177E, I178M, Q207A, R211S, F214L, K238R, V245DCRF01_AE
Han (2010)LN121LN121FJ531418NoneNone  E6D, K11T, V35T, T39R, K43E, S68G, K102R, K122E, D123N, S162C, K173R, Q174K, D177E, I178M, E203D, Q207A, R211S, K238R, V245ECRF01_AE
 LN179LN179FJ531434NoneNone  E6D, K11T, V35T, T39K, S68G, K103R, K104R, K122E, D123S, I135T, K173I, Q174K, D177E, V179I, T200I, Q207A, R211S, F214L, V245E, V276ICRF01_AE
 LN106LN106FJ531447NoneNone  E6D, K11T, V35T, T39K, S68G, K103R, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, V276ICRF01_AE
Jullaksorn (2010)CR03CR0-3Apr08RGQ857132NoneNone  E6D, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, I159V, K173A, Q174K, D177E, Q207A, R211S, V245E, K249R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491P, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
  CR03-Jul08RGQ857164NoneNone  E6D, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, I159V, K173V, Q174K, D177E, Q207A, R211S, V245E, K249R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491P, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
  CR03-Jan09DGQ857228NoneNone  E6D, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, I159V, K173A, Q174K, D177E, Q207A, R211S, V245E, K249R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491P, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 CR04CR04-Apr08RGQ857133NoneNone  E6D, V35T, T39K, K43E, S68G, V106I, K122E, D123E, K166R, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E297A, E312A, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, E399D, A400T, T403M, E432D, A446AV, N447S, D471E, Q480H, H483Q, L491S, E514D, E516D, L517V, S519N, Q524E, E529D, K530R, A534S, A554SCRF01_AE
  CR04-Jul08RGQ857165NoneNone  E6D, V35T, T39K, K43E, S68G, V106I, K122E, D123E, K166R, K173I, Q174K, D177E, I178M, T200V, Q207D, R211K, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, H315C, S322L, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, E399D, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, E514D, E516D, L517V, S519N, Q524E, E529D, K530R, A534SCRF01_AE
  CR04-Oct08RGQ857195NoneNone  E6D, V35T, T39K, K43E, S68G, K122E, D123E, I135T, K166R, K173I, Q174K, D177E, I178M, T200I, E203D, Q207A, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, H315R, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, E399D, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, E514D, E516D, L517V, S519N, Q524E, E529D, K530R, A534S, A554SCRF01_AE
  CR04-Jan09DGQ857229NoneNone  E6D, V35T, T39K, K43E, S68G, K122E, D123E, K166R, K173I, Q174K, D177E, I178M, T200I, Q207D, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, E399D, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, E514D, E516D, L517V, S519N, Q524E, E529D, K530R, A534S, A554SCRF01_AE
  CR04-Apr09DGQ857261NoneNone  E6D, V35T, T39K, K43E, S68G, V106I, K122E, D123E, K166R, K173I, Q174K, D177E, I178M, T200I, Q207D, R211K, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, H315C, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, E399D, A400T, T403M, E432D, N447S, V466I, D471E, Q480H, H483Q, L491S, E514D, E516D, L517V, S519N, Q524E, E529D, K530R, A534SCRF01_AE
Phan (2010)ND16ND16AB519457NoneNone  E6N, V35T, T39K, K43R, S68G, K122E, D123S, I135R, S162Y, K173I, Q174K, D177E, I178M, Q207S, R211SCRF01_AE
 O925O925AB519496NoneNone  E6D, V8I, K11T, V35T, T39K, K43Q, V60I, S68G, D121H, K122E, I135T, T139A, K173R, Q174K, D177E, I178M, T200A, Q207A, R211SCRF01_AE
Selimova (2010)17MOS17MOSHM345549NoneNone  T27S, E36D, T39K, S68G, D123N, K173L, Q174K, D177E, T200I, Q207A, R211S, V245M, E248D, Y271YF, A272P, V276VI, T286A, E291D, V292I, I293V, P294T, L295M, K311RCRF01_AE
Dean (2011)IVVI7155IVVI7155JQ312407NoneNone  T39E, S68G, K122E, D123NS, S162C, K173T, Q174K, D177E, I178LM, Q207A, R211S, K238R, V245ECRF01_AE
 IVVI7201IVVI7201JQ312409NoneNone  T39K, S68G, K122E, D123N, T139A, S162C, K173T, Q174K, D177E, I178M, Q207A, R211S, K238KR, V245ECRF01_AE
 IVVI7390IVVI7390JQ312419NoneNone  T39EK, S68G, D123N, I135T, S162C, K173I, Q174K, D177E, I195IL, Q207A, R211S, K238R, V245ECRF01_AE
Kao (2011)Pat37921152HQ657661NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, D121Y, K122E, D123E, I135T, K173A, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, P294T, E312NCRF01_AE
 Pat07436544HQ657966NoneNone  E6D, K11T, V35PT, T39K, K43E, V60VI, S68G, K122E, D123N, I135T, T165TI, K173IT, Q174K, T200A, Q207A, R211S, K238R, I244IV, V245E, K275KQ, T286A, E291ED, V292VI, I293V, E312T, I326IV, I329VCRF01_AE
 Pat04836629HQ657992NoneNone  E6D, V35T, T39K, V60I, S68G, K166KR, K173I, Q174K, D177E, I178M, G196GR, T200IM, Q207A, R211S, K238R, V245E, V276VI, T286TA, A288AS, E291D, V292I, I293V, L310I, E312N, I329VCRF01_AE
Lazaro (2011)AG-M16AG-M16HQ542721NoneNone  V35T, T39K, K43E, S68G, K122E, D123S, I135R, K173I, Q174K, D177E, I178M, T200L, Q207A, R211S, K238RCRF01_AE
 TG-M2TG-M2HQ542766NoneNone  K11T, V35T, T39K, S68G, D123DN, S162C, K173IV, Q174K, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
Su (2011)LZ2011LZ2011HQ588185NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K173I, Q174K, D177E, T200I, Q207A, R211S, V245E, K275RCRF01_AE
 LZ2107LZ2107HQ588208NoneNone  E6D, K11T, V35T, E36D, T39K, K43E, S68G, K122E, D123S, I135R, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 LZ2141LZ2141HQ588222NoneNone  E6D, K11T, K22R, V35T, T39K, K43E, V60I, S68G, T107S, K122E, D123S, K173I, Q174K, D177E, T200I, Q207A, R211S, V245ECRF01_AE
 GXNN5927GXNN5927HQ588235NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245ECRF01_AE
Telan (2011)09MM_09-856709MM_09-8567AB587097NoneNone  E6D, V35T, T39R, V60I, S68G, D121H, K122E, D123S, K173T, Q174K, D177E, T200A, Q207A, R211S, K238R, V245E, K281RCRF01_AE
 10MC_01-5210MC_01-52AB587106NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, D121H, K122E, D123S, I135R, K173L, Q174K, D177E, I180V, T200E, E203D, Q207A, R211S, V245E, V276ICRF01_AE
Ye (2011)BJ07149BJ07149JF906577NoneNone  E6D, V35I, T39K, K43E, S68G, K122E, D123S, I135T, K173T, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293VCRF01_AE
 BJ07268BJ07268JF906600NoneNone  E6D, V35T, T39K, K43E, S68G, K103R, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, R206RK, Q207A, R211S, F214L, K238R, V245E, V276I, T286A, E291D, V292I, I293VCRF01_AE
 BJ07368BJ07368JF906623NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, S162C, K173R, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, I293VCRF01_AE
Chen (2012)YN09DH0032YN09DH0032JQ658502NoneNone  E6D, K11A, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, I195L, T200I, Q207A, R211S, K238R, V245E, A272P, T286A, V292I, I293VCRF01_AE
 YN09DH0146YN09DH0146JQ658603NoneNone  G45GR, S68G, W88W*, K101R, I135V, T139TA, K173I, Q174K, D177E, T200I, Q207A, R211S, K238KR, V245E, K277R, T286ACRF01_AE
 YN09DH0150YN09DH0150JQ658607NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, I135T, K173I, Q174K, Q207E, K238R, V245E, V276I, T286A, E291D, V292I, I293VCRF01_AE
 YN10DH0076YN10DH0076JQ658697NoneNone  E6D, K11KT, V35T, T39K, K43KE, V60VI, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178IL, Q207A, R211S, K238R, V245E, V276VI, L283LI, T286A, E291ED, V292VI, I293VCRF01_AE
 YN10DH0080YN10DH0080JQ658701NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, S162C, K173I, Q174K, D177E, Q207A, L210M, R211S, K238R, V245E, K249KR, A272P, E291D, V292I, I293VCRF01_AE
Chow (2012)11FIR16411FIR164JX390610NoneNone  E6N, V35T, T39K, K43E, V60I, S68G, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238R, V245E, K249R, T286A, E291D, V292I, I293V, P294Q, L295LM, E297EK, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, E432D, V458I, D471E, Q480H, L491S, L517V, S519N, Q524E, A534S, A554KCRF01_AE
De Gascun (2012)IRL08974IRL08974JN622224NoneNone  K43E, V60I, S68G, K122E, D123S, K173I, Q174K, D177E, R206RK, Q207A, R211S, E224EGCRF01_AE
 IRL12973IRL12973JN622225NoneNone  I50IF, S68G, W71W*, K122E, D123N, I135T, Q145QH, K173I, Q174K, D177E, I178M, G196E, E203EDKN, Q207AT, R211S, F214LCRF01_AE
 IRL54561IRL54561JN622233NoneNone  K43E, S68G, D121H, K122E, D123S, I135T, T139A, K173I, Q174K, D177E, Q207A, R211SCRF01_AE
Karlsson (2012)SE_291SE_291JQ698866NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, I135T, T165A, K166R, K173S, Q174K, D177E, I178M, T200I, E203D, Q207A, R211S, K238R, V245D, E248VCRF01_AE
Kijak (2012)05TH13008705TH130087JN248339NoneNone  E6D, V8I, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, E169D, Q174R, I178M, G196E, Q207A, R211S, K238R, V245K, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, R356K, M357K, G359S, K366R, A371V, T386I, K390R, A400T, T403M, E432D, S468A, T470N, D471E, Q480H, L491S, L517I, S519N, Q524E, E529D, A534S, Q547K, A554SCRF01_AE
 04TH10754204TH107542JN248318NoneNone  E6D, K11T, V35T, T39K, K43AE, V60I, S68G, D121H, K122E, D123N, I135T, K173I, Q174K, D177E, T200K, I202V, Q207A, L210S, R211S, V245E, E248ED, A272P, T286A, V292I, E312T, D324E, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 05TH12733105TH127331JN248338NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K102R, D121H, K122E, I135T, K173I, Q174K, D177E, T200K, I202V, Q207A, L210S, R211S, K238R, V245E, L260LF, A272P, T286A, E291ED, V292I, I293V, P294T, E312T, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, V417VI, E432D, V435VI, T470TA, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, I526IK, A534S, A554SCRF01_AE
 04TH70432004TH704320JN248331NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123N, K173I, Q174K, D177E, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554SCRF01_AE
Rolland (2012)AA007a_WG14AA007a_WG14JX446760NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173R, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, P294Q, E312T, P313T, I326V, I329V, R356K, M357K, G359S, K366R, A371V, T386I, K390R, A400T, T403M, E432D, N447S, Q464K, K465R, V467I, S468T, D471E, Q480H, H483Y, V496I, K512R, L517V, S519N, I522V, Q524E, A534S, A554SCRF01_AE
 AA008a_LH15AA008a_LH15JX446769NoneNone  E6D, K11A, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, S162Y, K166R, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, P243A, V245E, T286A, E291D, V292I, I293V, E312N, I326V, I329V, G335D, K350R, M357K, G359S, K366R, A371V, I375V, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S, I556V, K558RCRF01_AE
 AA012a_LH8AA012a_LH8JX446832NoneNone  E6D, K11S, V35T, T39K, K43E, V60I, S68G, K122E, D123S, K173A, Q174K, D177E, T200A, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357Q, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, D460N, D471E, Q480H, H483Y, L491P, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 AA014a02LAA014a02LJX446859NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, K173I, Q174K, D177E, I178M, T200K, Q207A, R211S, K238R, V245Q, A272G, T286A, E291D, V292I, I293V, K311N, E312T, I329V, G335D, M357K, G359S, K366R, A371V, S379G, V381I, K388R, K390R, A400T, K424Q, E432D, N447S, L452Q, V466I, V467I, T470N, D471E, K476Q, Q480H, H483Y, L491S, I505V, K512R, L517V, Q524E, K527R, A534S, A554SCRF01_AE
 AA015a_LH1AA015a_LH1JX446869NoneNone  K11T, V35T, T39K, K43E, S68G, D123S, I159V, K173I, Q174K, D177E, I178M, Q207A, R211S, V245K, T286A, E291D, I293V, K311R, E312T, D324E, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, R448K, D471E, Q480H, L491P, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 AA020a_wg2AA020a_wg2JX446927NoneNone  E6D, V35T, T39K, K43E, K49R, S68G, K122E, D123S, A158S, S162A, E169D, K173R, Q174K, D177E, T200A, Q207A, R211S, V245E, T286A, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T386I, K395R, A400T, T403M, E432D, N447S, R463K, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, A554TCRF01_AE
 AA031a_LH2AA031a_LH2JX447069NoneNone  I5V, E6D, K11A, V35I, T39N, S68G, K122E, D123N, I135T, S162C, K173T, Q174K, D177E, T200I, I202V, Q207A, R211S, Q222R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, K390R, E399D, A400T, T403M, E432D, D471E, Q480H, H483Q, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 AA051b03LAA051b03LJX447291NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173R, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, P294Q, E312T, P313T, I326V, I329V, M357K, G359S, K366R, A371V, T386I, K390R, A400T, T403M, E432D, N447S, Q464K, K465R, V467I, S468T, D471E, Q480H, H483Y, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 AA062b03LAA062b03LJX447392NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, V276I, E291D, V292I, I293V, E312T, V317A, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T386I, K390R, K395R, A400T, T403M, E432D, N447S, T470S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 AA066a07LAA066a07LJX447440NoneNone  E6D, V35T, T39K, K43E, V60I, K66R, S68G, K122E, D123S, I135V, I142V, K173V, Q174K, D177E, I178M, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 AA068a_23AA068a_23JX447469NoneNone  E6D, V8I, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135V, K173I, Q174E, D177E, I178M, V179I, T200A, Q207T, R211K, K238R, V245E, K249R, S251H, T286A, E291D, V292I, I293V, P294Q, E312T, I326V, I329V, G335D, R356K, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E404D, E432D, N447S, R448K, D460N, T470S, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524E, A534S, A554T, K558RCRF01_AE
 AA072a05AA072a05JX447504NoneNone  E6D, V35T, T39K, K43E, P55PL, V60I, S68G, K103R, K122E, D123S, I135T, S162C, K173S, Q174K, D177E, Q207A, V245E, A272P, T286A, E291D, V292I, I293V, K311T, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I380V, T386A, K390R, K395R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 AA074a01LAA074a01LJX447524NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123N, I135T, K173V, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357Q, G359S, K366R, A371V, I382L, K390R, K395R, A400T, T403M, E432D, V435I, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 AA084a_wg4AA084a_wg4JX447673NoneNone  K32I, V35T, T39K, S68G, K122E, D123S, I135R, I142T, S162N, K173I, Q174K, R199K, T200I, Q207S, R211S, K238R, V245E, T286A, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359T, K366R, T369A, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524D, A534S, A554SCRF01_AE
 AA099a_WG10AA099a_WG10JX447885NoneNone  E6D, K11T, V35T, T39K, K43A, S68G, K122E, D123N, I135T, K166R, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, V276I, E291D, I293V, A304E, E312T, I326V, I329V, G335D, K347R, K350R, M357K, G359S, K366R, A371V, K385R, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S, K558RCRF01_AE
 AA100b07LAA100b07LJX447895NoneNone  E6D, V8I, K11T, V35T, T39K, S68G, K122E, D123S, K173I, Q174K, D177E, I178V, T200I, Q207A, R211S, K238R, V245E, A272P, K277R, T286A, E291D, V292I, I293V, E312T, I329V, G335D, K350R, M357K, G359S, K366R, A371V, I375V, K395R, A400T, T403M, E432D, V435A, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, E546D, A554SCRF01_AE
 AA109a05LAA109a05LJX448038NoneNone V179DE6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135K, K166R, K173I, Q174K, D177E, T200I, Q207A, R211S, V245E, A272P, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, A371V, T377M, K390R, A400T, T403M, E432D, A446S, D471E, Q480H, H483Y, L491A, K512R, L517V, S519N, Q524E, E529D, A534S, A554SCRF01_AE
 AA111a_WG11AA111a_WG11JX448059NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179I, E194D, T200A, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312N, D324E, I329V, G335D, Q336R, M357K, G359S, K366R, A371V, K388R, K390R, A400T, T403M, E432D, V435A, N447S, D471E, Q480H, L491S, K512R, L517V, Q524E, E529D, A534S, A554S, K558RCRF01_AE
 AA112a05LAA112a05LJX448068NoneNone  E6D, V35T, T39K, K43E, S68G, K122E, D123S, I135R, S162Y, K166R, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, I329V, G335D, K350R, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, D460N, L469I, D471E, Q480H, H483Y, L491S, I505V, K512R, L517I, S519N, Q524E, A534S, A554S, K558RCRF01_AE
 AA118a_07LAA118a_07LJX448157NoneNone  E6D, V8I, K11T, V35T, T39K, S68G, K122E, D123S, K173I, Q174K, D177E, I178V, T200I, Q207A, R211S, K238R, V245E, A272P, K277R, T286A, E291D, V292I, I293V, E312T, I329V, G335D, K350R, M357K, G359S, K366R, A371V, I375V, K395R, A400T, T403M, E432D, V435A, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, E546D, A554SCRF01_AE
 AA131a01LAA131a01LJX448311NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123N, K173I, Q174K, D177E, I178M, V189I, E203D, Q207A, R211S, V245E, T286A, E291D, V292I, I293V, P294L, E312T, I329V, G335D, M357K, G359S, K366R, A371V, S379G, K390R, A400T, T403M, E432D, N447S, D460N, T470N, D471E, Q480H, L491P, K512R, L517I, S519N, Q524E, K527N, A534S, A554SCRF01_AE
Telan (2012)90985679098567AB747381NoneNone  E6D, V35T, T39R, V60I, S68G, D121H, K122E, D123S, K173T, Q174K, D177E, T200A, Q207A, R211S, K238R, V245E, K281RCRF01_AE
 10027641002764AB747389NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, D121H, K122E, D123S, I135R, K173L, Q174K, D177E, I180V, T200E, E203D, Q207A, R211S, V245E, V276ICRF01_AE
 100152100152AB747401NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, D121H, K122E, D123S, I135R, K173L, Q174K, D177E, I180V, T200E, E203D, Q207A, R211S, V245E, V276ICRF01_AE
 10086781008678AB747421NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, D121H, K122E, D123S, I135R, K173L, Q174K, D177E, T200E, E203D, Q207A, R211S, V245E, V276ICRF01_AE
 110318367110318367AB747444NoneNone  E6D, V35T, T39R, V60I, S68G, D121H, K122E, D123N, K173T, Q174K, D177E, T200A, Q207A, R211S, K238R, V245E, K281RCRF01_AE
 1106362611063626AB747457NoneNone  E6D, V35T, T39K, K43E, S68G, K122E, D123S, I135T, R172K, K173I, D177E, I178M, T200A, E204K, Q207A, R211S, K238R, V245E, A272G, K277RCRF01_AE
 1108471711084717AB747461NoneNone  V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, I159V, K173I, Q174K, D177E, V179I, T200A, E204Q, Q207A, R211S, V245ECRF01_AE
 1203191112031911AB747518NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, V245ECRF01_AE
Tran (2012)HPA093HPA093AB690992NoneNone  I5V, E6D, K11T, V35T, T39K, S68G, K122E, D123S, S162C, K173R, Q174K, D177ECRF01_AE
 HPV2_124HPV2_124AB691072NoneNone K101EK11T, V35T, T39I, V60I, S68G, K122E, D123S, I135R, S162C, K173T, Q174K, D177E, I178M, Q207G, R211S, K238R, V245ECRF01_AE
Trinh (2012)VN-20VN-20HQ876622NoneNone  E6D, K11T, V35T, T39K, S68G, K122E, D123S, I135T, S162C, K173R, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 VN-54VN-54HQ876640NoneNone  E6D, V35T, T39K, K43E, V60I, K66R, S68G, K122E, D123S, I135T, S162Y, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245ECRF01_AE
Yang (2012)37113711JQ617187NoneNone  E6D, K11T, V35T, T39EK, S68G, T69A, D123N, I135T, S162C, K173I, Q174K, D177E, I178IM, G196GE, Q207A, R211S, K238R, V245ECRF01_AE
 37353735JQ617211NoneNone  I5V, E6D, K11KT, E28A, V35T, T39E, S68G, V90VI, K122E, D123NS, I135T, T165TI, K166KR, K173IL, Q174K, D177E, I178M, V179I, G196E, T200TA, Q207A, R211S, K238R, V245ECRF01_AE
 37553755JQ617231NoneNone  E6D, V35T, T39K, K43E, S68G, V118I, K122E, D123S, I135AT, I142IV, S162SC, K173I, Q174KN, D177E, I178IM, T200IL, Q207A, R211S, K238R, V245ECRF01_AE
Yang (2012)GZ227GZ227JN848838NoneNone  E6D, K11T, K20R, V35T, T39K, K43E, S68G, K122E, D123S, S134G, E138A, T139I, Q145R, N147C, W153G, A158P, Q161H, S163C, M164L, R172K, K173I, Q174K, D177E, I180L, T200I, Q207A, R211S, K238R, V245E, A272P, T286A, E291D, V292I, I293VCRF01_AE
 GZ186GZ186JN848840NoneNone  E6D, K11T, V35T, T39K, S68G, K122E, D123S, S162N, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, A272P, V276VI, K281R, T286TA, E291D, V292I, I293VCRF01_AE
 GZ107GZ107JN848847NoneNone  I2V, E6D, K11T, K20R, V35T, T39K, K43E, V60I, S68G, V106I, K122E, D123N, T139A, I167IV, K173IT, Q174K, D177E, I178L, T200R, Q207A, L210M, R211S, K238R, V245E, T286A, E291D, V292I, I293VCRF01_AE
 GZ125GZ125JN848872NoneNone  E6D, K11T, K20R, V35T, T39K, K43E, S68G, V106I, K122E, D123S, K173I, Q174K, D177E, I178L, T200I, Q207A, L210S, R211S, K238R, V245E, T286A, E291D, V292I, I293VCRF01_AE
 GZ189GZ189JN848883NoneNone  E6D, K11T, V35T, T39K, S68G, K122E, D123S, S162N, K173I, Q174K, D177E, I178M, T200TI, Q207A, R211S, K238R, V245E, A272P, V276I, K281R, T286A, E291D, V292I, I293VCRF01_AE
 GZ106GZ106JN848892NoneNone  I2V, E6D, K11T, K20R, V35T, T39K, K43E, V60I, S68G, V106I, K122E, D123N, T139A, K173I, Q174K, D177E, I178L, T200R, Q207A, L210M, R211S, K238R, V245E, T286A, E291D, V292I, I293VCRF01_AE
Frentz (2013)EHR-19229EHR-19229JX299858NoneNone  K11T, V35T, E36D, T39R, S68G, K122E, D123N, K166R, K173L, Q174K, D177E, Q207A, V245MCRF01_AE
 EHR-20653EHR-20653JX299879NoneNone  E6K, K11T, V35I, E36D, T39K, S68G, V106VI, K122E, D123S, A158S, K173S, Q174K, D177E, Q207A, R211S, V245MCRF01_AE
 EHR-38778EHR-38778JX300196NoneNone  E6D, V35T, T39K, K43E, S68G, V106I, K122DE, D123NS, I135T, S162A, K173IL, Q174K, P176S, I178M, T200A, Q207A, R211S, V245ECRF01_AE
 EHR-46864EHR-46864JX300323NoneNone  E6D, K11A, V35I, E36EG, T39E, S68G, T69S, D121DE, K122E, D123S, K166KR, K173IL, Q174K, D177E, I178M, T200M, Q207A, R211S, V245ECRF01_AE
 EHR-50832EHR-50832JX300387NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, I132IV, I135IT, K173L, Q174K, D177E, I178M, Q207A, K238R, V245VECRF01_AE
 EHR-61118EHR-61118JX300556NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 EHR-66519EHR-66519JX300657NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, K173AV, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 EHR-77855EHR-77855JX300882NoneNone  K11T, V35T, E36D, T39K, E40D, S68G, K122E, D123S, I135T, T165I, K173L, Q174K, D177E, V179I, Q207A, R211S, F214L, V245MCRF01_AE
Hawke (2013)1131945211319452KC237891NoneNone  E6D, K11T, V35T, T39K, S68G, K122E, D123N, S162C, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 6141821 H6141821 HKC238201NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122KE, D123DGNS, K173V, Q174K, D177E, V179T, T200A, Q207A, R211S, V245E, K249Q, A272P, T286A, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, S379G, I382T, K388R, K390RCRF01_AE
 9021391290213912KC238231NoneNone  E6ED, V8VI, K11ST, E28A, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, T165I, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 9275799 H9275799 HKC238277NoneNone  E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135R, K173I, Q174K, D177E, I178M, T200A, I202IL, Q207A, R211S, K238R, V245DCRF01_AE
Li (2013)28282828JQ901042NoneNone  E6D, K11T, D17DE, V35T, T39R, K43E, V60I, S68G, K122E, D123S, I135R, S162C, K173R, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, K275R, K277R, T286A, E291D, V292I, I293V, E312T, V317T, I326V, G335D, M357T, G359S, K388R, K390R, A400T, N447S, D471E, Q480H, L491S, V493L, K512R, L517T, S519N, Q524E, A534S, I556VCRF01_AE

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