Reverse Transcriptase Inhibitors

HOME Genotype-Rx Genotype-Pheno Genotype-Clinical hivdb program

Reverse Transcriptase Inhibitors

Subtype	CRF01_AE
Gene	RT
Mutation	D67N
Rx	>= 1 NRTI (but no NNRTI)
IncludeMixtures	No

References	6
Patients	127
Isolates	130

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	NRTIs	NNRTIs	NRTIDRMs	NNRTIDRMs	OtherMut	Subtype
Ariyoshi (2003)	JPN12	JPN12A		AZT, DDI, 3TC, D4T	None	M41L, D67N, K70R, V75VIM, M184V, T215FV, K219Q		E6D, K11T, K20R, V35T, T39K, K43E, V60I, K64KHNQ, T69N, D121H, K122E, D123S, I135IT, I167IV, K173I, Q174K, D177E, T200I, Q207A, R211S, F214FL, D218DE, L228LH, K238R, V245E	CRF01_AE
		JPN12B	AY901413	AZT, DDI, 3TC, D4T	None	M41L, D67N, K70R, V75M, M184V, T215F, K219Q		K20R, V35T, T39K, K43E, V60I, K64H, T69N, D121H, K122E, D123S, S162SDGN, I167V, K173I, Q174K, D177E, T200I, Q207A, R211S, D218E, L228H, K238R	CRF01_AE
	JPN13	JPN13A		AZT, DDI	None	M41L, D67N, T69D, K70R, T215Y, K219Q		E6D, K11T, V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, V179I, G196GE, T200I, E204Q, Q207A, R211S, L228H, K238R, V245E	CRF01_AE
		JPN13B	AY901414	AZT, DDI	None	M41L, D67N, T69D, K70R, T215F, K219Q		V35T, T39K, K43E, V60I, S105ST, K122E, D123S, K173M, Q174K, D177E, V179I, G196E, T200I, E204Q, Q207A, R211S, L228H, K238R	CRF01_AE
	JPN15	JPN15	AY901416	AZT, DDI, DDC, 3TC, D4T	None	M41L, D67N, V75M, M184V, L210W, T215Y, K219N		E6N, K11T, V35T, T39K, K43E, V60I, V118VI, K122E, D123S, I135T, K173IV, Q174K, D177E, G196GE, Q207A, R211S, K238R, V245E	CRF01_AE
	JPN34	JPN34		AZT, 3TC	None	D67N, M184V		E6D, V8I, K11T, V21I, V35T, T39K, K43E, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E	CRF01_AE
	JPN19	JPN19A		AZT, 3TC	None	D67N, M184V		E6D, K11T, V35T, T39K, K43E, K122E, D123N, S162C, P170S, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E	CRF01_AE
		JPN19B	AY901417	AZT, 3TC	None	D67N, K70R, M184V		E6D, K11T, V21VI, V35T, T39K, K43E, K122E, D123N, S162C, P170PS, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, E224ED, K238R, Q242QP, I244IV	CRF01_AE
	JPN38	JPN38	AY901419	AZT, DDI, 3TC	None	M41L, D67N, L210W, T215Y		E6D, V8I, K11T, V35T, T39K, K43E, R78RI, V118VI, K122E, D123S, K173I, Q174K, D177E, V179I, Q207A, R211S, K238R, V245E	CRF01_AE
	JPN39	JPN39	AY901420	AZT, D4T, 3TC	None	D67N, K70R, M184V, K219Q		E6D, K11T, V35T, T39K, K43E, T69TN, K102E, K122E, D123S, I135IV, S162Y, K173R, Q174K, D177E, T200A, Q207A, R211A, K238R, V245K	CRF01_AE
	JPN1	JPN1		AZT, DDC	None	D67N, K70R, T215F		E6D, K11T, V35P, T39K, K43E, K104N, K122E, D123S, I135T, K173R, Q174K, D177E, I178M, V179I, Q207A, R211S	CRF01_AE
	JPN5	JPN5		AZT, DDI, DDC	None	D67N, K70R, T215FI, K219Q		E6D, V8I, K11T, V35T, T39K, K43E, V60VI, K122E, D123N, I135IV, K173IT, Q174K, D177E, Q207A, R211S, K238R, V245E	CRF01_AE
	JPN25	JPN25	AY901426	AZT, DDI, 3TC, D4T	None	M41L, D67N, L210W, T215Y	A98G	E6D, K11T, V35T, T39K, K43E, E44D, V118I, D123N, I135T, K173I, Q174K, D177E, T200K, K201I, E204EV, Q207A, H208Y, R211N, K238R, V245E	CRF01_AE
Montes (2004)	MB_patMOU	00_MOUL723	AJ577956	AZT, DDI, D4T, 3TC	None	D67N, K70S, M184V, T215Y		K11T, V35T, E36A, T39K, K43E, D121H, K122E, D123S, I135T, I142V, S162Y, F171Y, K173S, D177E, V179I, T200A, Q207A	CRF01_AE
	MB_patPOI	01_POI735	AJ577975	AZT, DDI, D4T, 3TC	None	D67N, T69D, K219Q		E6D, K11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, R206K, Q207A, R211S	CRF01_AE
Hsu (2005)	BAA150606	BAA150606	AY870151	AZT, 3TC, D4T	None	D67N, K70R, M184V, K219Q		E6D, K11T, K22R, V35T, T39K, K43E, K122E, D123S, I135L, K166R, R172RK, K173I, Q174K, D177E, T200A, Q207A, R211S, V245K, V276I, T286A, E291D, V292I, I293V, E312T, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, V372I, K390R, K395R	CRF01_AE
	BAA150616	BAA150616	AY870155	D4T, DDI	None	D67N, K70R, K219Q, N348I		E6D, K11T, V35T, T39K, K43AE, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179I, Q207A, L210F, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K388R, K390R, K395R	CRF01_AE
	BAA154764	BAA154764	AY870165	AZT, 3TC, D4T, DDI	None	M41L, D67N, L210W, T215Y		E6D, V35IT, T39K, K43E, E44A, V111I, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, T200TI, Q207A, H208Y, R211RK, K238R, V245E, A272P, E291D, I293V, E312A, I329V, G335D, M357K, R358RG, G359S, K366R, A371V, A376V, K390R, K395R	CRF01_AE
	BAA154768	BAA154768	AY870166	AZT, 3TC, D4T, DDI	None	D67N, T69T_T, K70R, K219Q, N348IT		E6ED, V8VI, V35T, T39K, K43E, K64N, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, L228H, K238R, V245T, A272P, T286TA, E291D, V292VI, I293V, E312T, I326V, I329V, G335D, M357KR, G359S, K366R, T369TA, A371V, K390R, K395R	CRF01_AE
	BAA154770	BAA154770	AY870168	D4T, DDI, AZT, 3TC	None	D67N, T215F		E6D, V35T, T39K, K43E, T69S, V106VI, I135IT, S162SN, Q174D, D177E, I178V, V179I, T200I, I202V, E204K, Q207A, R211S, D218DE, V245E, K275KQ, T286A, A288T, E291ED, V292I, I293V, E312T, I329V, G335D, Y342F, M357K, G359S, K366R, T369A, A371V, K390R, K395R	CRF01_AE
	BAA157674	BAA157674	AY870179	AZT, 3TC	None	D67N, K70R, M184V, K219Q, N348I		V35T, T39K, K43E, K102R, K122E, D123S, S162C, K173I, Q174K, Q207A, R211S, K238R, V245E, A272P, K275R, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, E396D	CRF01_AE
	BAA157679	BAA157679	AY870184	AZT, 3TC	None	M41L, D67N, M184V, L210W, T215Y, N348IT		E6D, V21I, V35T, T39K, K43E, V60I, V106VI, V118VI, K122E, D123N, K173I, Q174K, D177E, I178M, G196E, Q207A, R211S, V245K, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, E399D	CRF01_AE
	BAA161414	BAA161414	AY870224	AZT, 3TC, D4T, DDI	None	D67N, K70R, K219Q		E6D, K11S, V35T, T39K, K43E, K49R, V60I, K122E, D123NS, I135T, K173I, Q174K, D177E, I178M, T200A, Q207D, R211I, K238R, V245E, K277KR, K281R, T286A, I293V, E297K, E312T, V317VA, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, K390R, K395R	CRF01_AE
	BAA161420	BAA161420	AY870227	D4T, 3TC, DDI	None	D67N, K70R, T215Y, N348NI	Y181C, G190A	E6D, V35T, T39K, K43E, K122E, D123S, I135T, E138EQ, K173I, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395KR	CRF01_AE
	BAA161422	BAA161422	AY870228	AZT, 3TC, D4T, DDI	None	D67N, K70R, M184V, K219KEGR		E6D, K11S, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, E194ED, Q207A, R211S, V245E, A288T, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R	CRF01_AE
	BAA161424	BAA161424	AY870229	D4T, DDI	None	D67N, K70R		E6D, E28EK, V35T, T39EK, K43KE, K122E, D123S, S162SN, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, A272P, K281R, T286A, E291D, V292I, I293V, A304E, E312T, I326V, I329V, G335D, M357K, G359S, T369A, A371V, K390R	CRF01_AE
	BAA161439	BAA161439	AY870235	D4T, DDI	None	D67N, K70R, K219Q		E6D, V8I, K11T, V35T, T39K, K43E, K122E, D123NS, I135T, K166R, K173I, Q174K, D177E, V179VI, T200I, I202V, Q207A, R211S, K238R, V245E, A272AG, I274IV, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, A371V, T386I, K390R	CRF01_AE
	BAA161445	BAA161445	AY870238	D4T, DDI	None	D67N, T69T_T, K70R, L74LV, Q151M, K219Q		E6D, K11T, V35T, T39K, K43E, K64N, V90I, K122E, D123S, K173I, Q174K, D177E, V179I, T200I, Q207A, R211S, D218E, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366KR, A371V, A376AT, K390R, K395R	CRF01_AE
	BAA161451	BAA161451	AY870244	D4T, DDI	None	D67N, K70R, V75M, M184V, T215F, K219W		E6D, V35T, E36D, T39K, K43E, V60I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, G196E, Q207A, R211K, K238R, V245EK, T286A, A288KR, E291D, V292I, I293V, E312T, P321S, I326V, I329V, G335D, M357R, G359S, K366R, A371V, T386I, K390R, K395R, E399D	CRF01_AE
Non-B Workgroup (2005)	TH_125	TH_125	AY605548	D4T, 3TC	None	D67N, K70R, M184V, K219Q		V35T, T39E, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211N, K238R, V245E, N255K, D256I, I257T, Q258P, K259Q	CRF01_AE
	TH_127	TH_127	AY605549	AZT, 3TC	None	M41L, D67N, K70R, L74I, T215F, K219Q		V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245K, D256E	CRF01_AE
	TH_128	TH_128	AY605550	AZT, DDI	None	M41L, D67N, L210W, T215Y		V35T, T39K, K43E, E44D, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, G196E, R206K, Q207A, R211D, K238R, V245E	CRF01_AE
	TH_130	TH_130	AY605553	AZT, 3TC	None	D67N, T69D, K70R, L74I, T215F, K219Q		V35T, T39K, K43E, V60I, K122E, D123S, K173T, Q174K, D177E, I178M, Q207A, R211S, K238R, V245K	CRF01_AE
	TH_141	TH_141	AY605554	D4T, DDI	None	D67N, K70R, V75T, K219Q		V35T, T39K, K43E, K64Y, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, D218E, V245K	CRF01_AE
	TH_143	TH_143	AY605556	AZT, DDI	None	M41L, D67N, L210W, T215Y		V35T, T39K, K43E, V60I, T69A, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I202V, Q207A, R211S, I244V, V245E, K249E	CRF01_AE
	TH_148	TH_148	AY605561	AZT, DDI	None	D67N, K70R, T215F, K219Q		V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_150	TH_150	AY605564	AZT, D4T, DDI	None	D67N, K70R, L74I, T215F, K219Q		P25A, V35T, T39K, K43E, K64H, T69N, V90I, D123N, R172K, K173I, Q174K, D177E, I178M, Q207A, R211S, D218E, V245K	CRF01_AE
	TH_153	TH_153	AY605565	AZT, DDI	None	M41L, D67N, L210W, T215Y		V35T, T39K, K43E, V60I, V118I, K122E, D123S, K173L, Q174K, D177E, I178M, Q207A, R211D, K238R, V245E	CRF01_AE
	TH_157	TH_157	AY605570	AZT, DDI	None	M41L, D67N, K70R, L210W, T215F, K219Q		D17G, G18R, K20R, V35T, T39K, K43E, E53D, V60I, L92M, V118I, K122E, D123S, S162Y, K173I, Q174K, D177E, I178M, Q207A, R211S, D218E, L228H, K238R, V245E, V254A	CRF01_AE
	TH_163	TH_163	AY605577	AZT, DDI	None	D67N, K70R, T215Y		P19T, V35T, T39K, K43E, K122E, D123S, K173T, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, D256E	CRF01_AE
	TH_165	TH_165	AY605579	AZT, DDI	None	M41L, D67N, T69D, L210W, T215Y		G18R, P19T, V35T, T39K, K43E, E44D, V60I, V118I, K122E, D123S, I135V, S162C, K173I, Q174K, D177E, T200I, Q207A, R211N, K238R, I244V, V245E, I257R, Q258P	CRF01_AE
	TH_166	TH_166	AY605580	AZT, DDI	None	M41L, D67N, K70R, T215Y, K219Q		V35T, T39K, K43E, V60I, V90I, K122E, D123N, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, D250R	CRF01_AE
	TH_169	TH_169	AY605583	AZT, DDI	None	D67N, K70R, T215F, K219Q		V35T, T39K, K43E, D76H, G93R, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245Q	CRF01_AE
	TH_170	TH_170	AY605584	3TC, D4T	None	M41L, D67N, K70R, M184I, T215F, K219Q		G18W, P19T, L34I, V35T, T39K, K43E, V60I, T69N, K122E, D123N, S162A, K173I, Q174K, D177E, E203K, Q207A, R211S, K223E, K238R, V245E	CRF01_AE
	TH_173	TH_173	AY605586	AZT, DDI	None	M41L, D67N, K70R, V75M, L210W, T215F, K219Q		K20R, V35T, T39K, K43E, V60I, K122E, D123S, I135L, S162D, R172K, K173I, Q174K, D177E, I178M, Q207A, R211K, D218E, L228H, V245E	CRF01_AE
	TH_180	TH_180	AY605589	D4T, DDI	None	M41L, D67N, T215Y		K20R, E28D, V35T, T39K, K43E, K122E, D123S, S162C, K173I, Q174K, D177E, I178L, T200I, Q207A, R211S, V245E	CRF01_AE
	TH_185	TH_185	AY605593	AZT, DDI	None	M41L, D67N, M184I, L210W, T215Y		K20R, V35T, T39K, K43E, E44A, V60I, V118I, K122E, D123S, K173I, Q174K, D177E, G196E, Q207A, R211N, V245E	CRF01_AE
	TH_189	TH_189	AY605595	AZT, DDI	None	D67N, T69D, K219Q		V21I, V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I178M, G196E, T200I, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_192	TH_192	AY605597	AZT, 3TC	None	D67N, K70R, M184V, T215F, K219Q		V35T, T39K, K43E, K49R, K122E, D123S, S162D, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_195	TH_195	AY605600	AZT, DDI	None	M41L, D67N, K70R, T215F, K219Q		E28D, E29D, V35T, T39K, K43E, E44D, T69A, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, E224D, M230I	CRF01_AE
	TH_197	TH_197	AY605602	AZT, DDI	None	M41L, D67N, L210W, T215Y		V35T, T39K, K43E, E44D, V60I, V118I, K122E, D123S, S162N, K173I, Q174K, D177K, I178M, Q207A, R211N, K238R	CRF01_AE
	TH_200	TH_200	AY605605	AZT, DDI	None	D67N, K70R, T215Y, K219Q		V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, V179I, Q207A, R211S, K238R, V245E, I257R, Q258D	CRF01_AE
	TH_206	TH_206	AY605610	AZT, DDI	None	M41L, D67N, K70R, L210W, T215F, K219Q		V35T, T39K, K43E, V60I, K122E, D123S, S162A, K173I, Q174K, D177E, I178M, Q207A, R211N, D218E, L228H, K238R, V245E, S251T	CRF01_AE
	TH_207	TH_207	AY605611	AZT, DDI	None	M41L, D67N, K70R, L210W, T215F, K219Q		D17G, G18W, P19T, V35T, T39K, K43E, V60I, V118I, K122E, D123S, R172K, K173I, Q174K, D177E, I178M, G196E, Q207K, R211S, D218E, V245K	CRF01_AE
	TH_212	TH_212	AY605615	AZT, DDI	None	M41L, D67N, L210W, T215Y		Q23T, W24V, P25A, V35T, T39K, K43E, V60I, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211G, K238R, V245E	CRF01_AE
	TH_213	TH_213	AY605616	AZT, DDI	None	D67N, K70R, T215F, K219Q		V35T, T39K, K43E, T69N, K122E, D123S, I159L, K173I, Q174K, D177E, V179I, G196E, T200A, Q207A, R211S, K238R	CRF01_AE
	TH_215	TH_215	AY605618	AZT, DDI	None	D67N, K70R, T215F, K219Q		V35T, T39K, K43E, K104N, D121H, K122E, D123S, I135V, S162A, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_225	TH_225	AY605631	D4T, 3TC	None	M41L, D67N, V75M, L210W, T215Y, K219Q		P19T, V35T, T39K, K43E, V60I, K122E, D123N, K173T, Q174K, D177E, I178M, T200A, Q207A, R211N, K223Q, L228H, K238R, V245E	CRF01_AE
	TH_230	TH_230	AY605636	AZT, DDI	None	M41L, D67N, L210W, T215Y		M16W, D17L, V35T, T39K, K43E, E44A, V60I, V118I, K122E, D123S, K173T, Q174K, D177E, T200A, Q207A, H208F, R211K, K238R, V245E	CRF01_AE
	TH_233	TH_233	AY605639	AZT, D4T, DDI	None	M41L, D67N, T69D, L210W, T215Y		V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, Q207A, R211K, V245E, K249R	CRF01_AE
	TH_419	TH_419	AY901832	AZT, DDI	None	D67N, K70R, T215I, K219Q		V35T, T39K, K43E, K122E, D123S, I135T, I142V, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_422	TH_422	AY901835	AZT, 3TC	None	D67N, K70R, M184V, K219Q		V35T, T39K, K43E, K49R, V60I, K122E, D123S, I135T, T165I, K173I, Q174K, D177E, T200I, Q207A, R211S, D218E, V245E	CRF01_AE
	TH_430	TH_430	AY901839	AZT, DDI	None	D67N, K70R, T215F, K219Q		K20R, V35T, T39K, K43E, V60I, T69N, K122E, D123S, Y127D, K173I, Q174K, D177G, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_433	TH_433	AY901840	D4T, DDI	None	M41L, D67N, L210W, T215Y		V35T, T39K, K43E, K122E, D123T, Y127D, S162C, K173I, Q174K, D177E, T200A, E203Q, Q207D, K238R	CRF01_AE
	TH_460	TH_460	AY901850	AZT, DDI	None	M41L, D67N, K70R, L210W, T215Y		V35T, T39K, K43E, V60I, K104N, K122E, D123N, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211K, K238R, V245E	CRF01_AE
	TH_470	TH_470	AY901851	AZT, DDI	None	D67N, K70R, K219Q		V35T, T39K, K43E, K122E, D123N, I135T, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V245K	CRF01_AE
	TH_474	TH_474	AY901853	D4T, DDI	None	M41L, D67N, T69D, K70R, V75L, L210W, T215Y		V35T, T39K, K43E, E44D, V60I, V118I, K122E, D123S, K173I, Q174K, D177E, Q207A, H208Y, R211N, V245K	CRF01_AE
	TH_494	TH_494		AZT, DDI	None	M41L, D67N, T215Y		V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_503	TH_503		AZT, DDI	None	D67N, K70R, K219Q		V35T, T39K, K43E, V90I, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, L228H, K238R, V245E	CRF01_AE
	TH_515	TH_515	AY901865	D4T, DDI	None	D67N, K70R, L74I, T215F, K219Q		V35T, T39E, V60I, K122E, D123N, I135T, S162A, K173I, Q174K, D177E, I178M, G196E, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_524	TH_524	AY901867	AZT, 3TC	None	D67N, K70R, M184V, K219Q		V35T, T39K, K43E, N57H, S162Y, K173I, Q174K, D177E, V179T, Q207A, R211S, V245E	CRF01_AE
	TH_525	TH_525		AZT, 3TC	None	D67N, K70R, M184V, K219Q		V35T, T39K, N57H, K122E, D123S, K173I, Q174K, D177E, T200A, Q207A, R211S, F214L, K238R, V245E	CRF01_AE
	TH_526	TH_526	AY901868	AZT, DDI	None	D67N, K70R, T215F		V35T, T39K, K43E, N81T, V111M, K122E, D123N, Y146V, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, V245E	CRF01_AE
	TH_529	TH_529	AY901871	AZT, DDI	None	M41L, D67N, L210W, T215F	F227L	V35T, T39K, K43E, N57Y, V60I, V118I, K122E, D123S, I135T, K173I, Q174K, I178M, T200I, Q207A, R211S, L228P, V245E	CRF01_AE
	TH_530	TH_530		D4T, DDI	None	D67N		V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, V245K	CRF01_AE
	TH_542	TH_542		D4T, DDI	None	D67N, T215Y, K219Q		V35T, T39K, K43E, K102N, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245K	CRF01_AE
	TH_543	TH_543		AZT, DDI	None	D67N, T215F, K219Q		V35T, T39K, K43E, K64N, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, E203G, Q207A, R211S, D218E, K238R, V245E, E248D	CRF01_AE
	TH_546	TH_546		AZT, DDI	None	D67N, K70R, K219Q		V35T, T39K, K43E, K64Y, W71R, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_551	TH_551	AY901875	AZT, 3TC, DDI	None	M41L, D67N, K70R, M184V, T215F, K219E	A98G	K20R, K22R, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, T200A, E203K, Q207A, R211S, L228H, V245K, K249Q, D250Y	CRF01_AE
	TH_552	TH_552	AY901876	AZT, DDI	None	D67N, T69D, K70R, T215F, K219Q		V35T, T39K, K43E, G45R, D121H, K122E, D123S, I135L, S162C, R172K, K173I, Q174K, D177E, I178L, Q207A, R211S, K238R	CRF01_AE
	TH_561	TH_561	AY901879	AZT, DDI	None	M41L, D67N, L210W, T215Y	E138K	K32I, V35T, T39K, K43E, V118I, K122E, D123S, S162Y, R172K, Q174E, D177E, I178V, Q207A, R211N, K238R, V245E	CRF01_AE
	TH_570	TH_570		D4T, DDI	None	D67N, K70R, K219Q		V35T, T39K, K43E, V60I, K122E, D123S, K173M, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_579	TH_579	AY901882	DDC, AZT	None	M41L, D67N, K70R, T215Y, K219Q		V35T, T39K, K43E, V60I, K102Q, K122E, D123N, S163C, K173I, Q174K, D177E, I178M, Q207A, R211S, D218E, K238R, V245E	CRF01_AE
	TH_583	TH_583	AY901883	AZT, 3TC, DDI	None	M41L, D67N, K70R, M184V, T215F, K219E		V35T, T39K, K43E, V60I, K102M, K122E, D123S, I135T, K173T, Q174K, I178M, G196E, T200I, E203K, Q207A, R211N, K238R, V245K	CRF01_AE
	TH_586	TH_586		AZT, DDI	None	D67N, K70R, K219Q		V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_587	TH_587		AZT, 3TC	None	M41L, D67N, M184V, L210W, T215Y		V35T, T39K, K43E, E44D, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211D, K238R, V245E	CRF01_AE
	TH_593	TH_593	AY901886	AZT, DDI	None	M41L, D67N, T69D, L210W, T215Y		V35T, T39K, K43E, V60I, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, E203D, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_594	TH_594	AY901887	AZT, DDI	None	M41L, D67N, L210W, T215Y		V35T, T39K, K43E, V111I, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_595	TH_595	AY901888	AZT, DDI	None	M41L, D67N, L210W, T215Y		V35T, T39K, K43E, K122E, D123S, I135L, S162Y, R172K, K173M, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_598	TH_598	AY901889	D4T, DDI	None	D67N, K70R, K219Q	V179D	V35T, T39K, K43E, K64Y, K102R, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, V245E	CRF01_AE
	TH_601	TH_601	AY901891	AZT, 3TC	None	M41L, D67N, L210W, T215Y	V179D	V35T, T39K, K43E, E44D, V111I, V118I, K122E, D123S, K166R, K173I, Q174K, I178L, T200A, E204D, Q207A, R211S, V245E	CRF01_AE
	TH_614	TH_614	AY901894	AZT, DDI	None	D67N, K70R, T215F, K219Q		V35T, T39K, K43E, K122E, D123S, Y146S, K173I, Q174K, D177E, I178M, G196E, Q197R, T200A, K238R	CRF01_AE
	TH_618	TH_618	AY901895	D4T, 3TC	None	M41L, D67N, K70R, M184I, L210W, T215Y, K219Q	A98G	V35T, T39K, K43E, V60I, K102Q, V118I, D123N, K173I, Q174K, D177E, T200A, Q207A, H208Y, R211S, K238R, V245E	CRF01_AE
	TH_621	TH_621	AY901897	D4T, DDI	None	D67N, K70R, K219Q		K20R, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, E203K, Q207N, R211S, K238R, V245E	CRF01_AE
	TH_623	TH_623		AZT, DDI	None	M41L, D67N, T215Y		V35T, T39K, K43E, K122E, D123S, S162Y, K173T, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E	CRF01_AE
	TH_627	TH_627		AZT, DDI	None	D67N, T215F		V35T, T39K, K43E, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, G196A, Q207A, R211S, V245E	CRF01_AE
	TH_628	TH_628	AY901900	D4T, DDI	None	D67N, K70R, K219Q		V35T, T39K, K43E, V60I, K64N, V111I, V118I, K122E, D123N, N136T, K173T, Q174K, D177E, Q207A, R211S, F214L, D218E, V245E	CRF01_AE
	TH_630	TH_630	AY901901	AZT, 3TC	None	D67N, K70R, T215F, K219Q		K20R, V35T, T39K, K43E, K122E, D123S, K126R, N136T, K173S, Q174K, N175I, D177E, I178M, T200I, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_632	TH_632	AY901902	DDC, AZT	None	D67N, K70R, T215F, K219Q		E28K, K32E, V35T, T39K, V60I, K122E, D123S, K173I, Q174K, D177E, V179T, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_637	TH_637	AY901905	AZT, DDI	None	D67N, K70R, T215F, K219Q		V35T, T39K, K43E, V106I, K122E, D123N, K173V, Q174K, D177E, V179I, Q207A, R211S, K238R, V245K	CRF01_AE
	TH_638	TH_638	AY901906	AZT, DDI	None	D67N, K70R, T215F, K219Q		V35T, T39K, K43E, V90I, K122E, D123S, K173I, Q174K, D177E, I178M, G196E, T200I, E203D, Q207A, R211K, K238R, V245K	CRF01_AE
	TH_643	TH_643	AY901908	AZT, DDI	None	M41L, D67N, L210W, T215Y	A98G	V35T, T39K, K43E, V60I, V118I, K122E, D123S, T139A, K173I, Q174K, D177E, I178M, Q207A, R211N, K238R, V245E	CRF01_AE
	TH_645	TH_645	AY901909	AZT, DDI	None	D67N, L74I, T215F, K219Q	A98G	V35T, T39K, K43E, T69N, K122E, D123S, K173I, Q174K, D177E, V179I, T200I, I202V, Q207A, R211S, K238R	CRF01_AE
	TH_655	TH_655	AY901918	AZT, DDI	None	M41L, D67N, T69D, L210W, T215Y		V35T, E44D, V118I, K122E, D123N, I135T, I142V, K173T, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E	CRF01_AE
	TH_656	TH_656		D4T, DDI	None	D67N, L210W, T215F		V35T, T39K, K43E, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_665	TH_665	AY901920	AZT, 3TC	None	M41L, D67N, M184V, L210W, T215Y	A98G	V35T, T39K, K43E, V118I, K122E, D123S, I135L, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, D237G, V245E, S251M	CRF01_AE
	TH_666	TH_666	AY901921	D4T, DDI	None	D67N, K70R, V75T, K219Q	Y181C	K20R, V35T, T39K, K43E, K64Y, K122E, D123S, K173A, Q174K, D177E, Q207A, R211S, D218E, L228H, K238R, V245E	CRF01_AE
	TH_669	TH_669	AY901923	AZT, DDI	None	D67N, K70R, K219Q		V35T, T39K, K43E, V60I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, L228R, K238R, V245E	CRF01_AE
	TH_699	TH_699		AZT, DDI	None	D67N, K70R, T215F, K219Q		K20R, V35T, T39K, K43E, K122E, D123S, S162Y, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_707	TH_707		AZT, DDI	None	D67N, K70R, M184V, K219Q		V35T, T39K, K43E, T69N, D121H, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_709	TH_709	AY901933	AZT, DDI	None	M41L, D67N, T215Y, K219Q		V35T, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R	CRF01_AE
	TH_711	TH_711		D4T, DDI	None	M41L, D67N, L74I, V75T, L210W, T215Y		K32I, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, G196E, T200I, Q207A, R211N, K238R, V245E	CRF01_AE
	TH_713	TH_713		AZT, DDI	None	M41L, D67N, L210W, T215Y		V35T, T39K, K43E, V60I, V118I, K122E, D123S, I135V, K173I, Q174K, D177E, Q207A, R211S, V245E	CRF01_AE
	TH_718	TH_718	AY901936	AZT, DDI	None	M41L, D67N, T69D, L210W, T215Y		V35T, T39K, K43E, E44D, V60I, K102Q, V118I, K122E, D123S, S162Y, E169D, Q174E, D177E, I178L, G196E, T200E, K201R, E204K, Q207A, R211D, K238R, V245E	CRF01_AE
	TH_719	TH_719		AZT, DDI	None	D67N, K70R, K219Q		V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_727	TH_727		AZT, DDI	None	D67N, K70R, T215Y, K219E		V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_728	TH_728	AY901939	D4T, DDI	None	D67N, K70R, K219Q		V35T, T39K, K43E, K64N, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, E203D, Q207A, R211S, V245E	CRF01_AE
	TH_748	TH_748		AZT, 3TC	None	D67N, T215F, K219Q		V35T, T39K, K43E, V60I, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, Q207A, R211S, V245E	CRF01_AE
	TH_756	TH_756	AY901948	AZT, 3TC, DDI	None	D67N, K70R, M184V, K219Q		V35T, T39K, K43E, D121H, K122E, D123S, I135T, K173I, Q174K, D177E, Q207A, R211S, K238R, V245E, E248D	CRF01_AE
	TH_778	TH_778	AY901954	D4T, DDI	None	D67N, K70R, K219Q		V35T, T39K, K43Q, K64N, V106I, K122E, D123S, S162Y, K173A, Q174K, D177E, E203K, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_779	TH_779	AY901955	AZT, 3TC	None	M41L, D67N, K70R, M184V, T215F, K219Q		V35T, T39K, K43Q, A98S, K122E, D123S, K173I, Q174K, D177E, T200A, I202V, Q207A, R211S, D218E, V245E	CRF01_AE
	TH_781	TH_781	AY901956	D4T, DDI	None	D67N, T69D, K70R, T215I, K219Q		T27S, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, L187W, L193K, T200I, Q207A, R211S, W229G, K238R, V245E	CRF01_AE
	TH_783	TH_783		D4T, DDI	None	D67N, K70R, K219Q		V35T, T39K, K43E, K64Y, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, L228H, K238R, V245E	CRF01_AE
	TH_402	TH_402		3TC, D4T	None	D67N, M184V		V35T, T39K, K43E, K102R, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E	CRF01_AE
	TH_403	TH_403		D4T, DDI	None	D67N, K70R, K219Q		V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, Q207A, R211N, K238R, V245K	CRF01_AE
	TH_414	TH_414		AZT, DDI	None	D67N, T69D, K70R, T215F, K219Q		K20R, V35T, T39E, V60I, K122E, D123S, I135V, S162C, K173I, Q174K, D177E, I178M, T200I, E203D, Q207A, R211K, L228H, K238R, V245E	CRF01_AE
	TH_415	TH_415		AZT, DDI	None	D67N, K70R, T215F, K219Q		V35T, T39K, K43E, K122E, D123S, I135L, R172K, K173M, Q174K, D177E, I178M, G196E, T200I, Q207A, R211K, L228R, K238R, V245E	CRF01_AE
	TH_416	TH_415		DDC, AZT	None	M41L, D67N, T215F		V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R	CRF01_AE
Tee (2006)	MYKL1364	03MYKL1364	AY960877	NRTI, AZT, 3TC	None	M41L, D67N, K70R, V75I, T215Y, K219Q	E138K	V35T, T39E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E	CRF01_AE
Ferradini (2011)	8	0323RT	HM026311	AZT, 3TC, DDI	None	M41ML, D67N, K70KR, L74LI, M184V, T215TFIS, K219Q	A98AG, K103KN, Y181YC, G190GA	V35T, T39K, K43KE, E53ED, V60VI, K122E, D123NS, K173IV, Q174K, D177E, I178IM, V179VI, T200TA, E203EK, Q207A, R211S, D218DE, K238R	CRF01_AE

Reverse Transcriptase Inhibitors

Database

Resources

Team