<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation K65R
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 3
Patients 8
Isolates 8
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Hsu (2005)BAA157671BAA157671AY870176D4T, DDINoneK65R, K70HN, K219R E6D, T27S, V35T, T39KN, V60I, S68G, K122E, D123N, I135T, K173I, Q174K, D177E, I178M, Q207A, R211NS, K238R, V245E, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, R356K, M357K, G359S, K366KR, A371V, K390R, K395R, A400TCRF01_AE
Non-B Workgroup (2005)TH_424TH_424AY901836D4T, DDINoneA62V, K65R, V75T, Q151M K20R, E28A, V35T, T39K, K43E, S68G, V106I, K122E, D123S, I135T, T165I, K173I, Q174K, D177E, I178M, I202V, Q207A, R211S, V245NCRF01_AE
 TH_481TH_481AY901856AZT, DDINoneA62V, K65R, V75I, F77L, F116Y, Q151M, K219Q V35T, T39K, K43E, S68G, T69I, K122E, D123S, K173I, Q174K, D177E, I202V, Q207A, R211S, V245ECRF01_AE
 TH_528TH_528AY901870D4T, DDINoneK65R, Q151M A33V, V35T, T39K, K43E, N57H, S68G, K122E, D123S, K173I, Q174K, D177E, I178L, T200I, Q207A, R211S, F214L, K238R, V245ECRF01_AE
 TH_556TH_556AY901878AZT, 3TCNoneK65R L34I, V35T, T39E, S68G, K102Q, K122E, D123N, S162N, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, V245ECRF01_AE
 TH_604TH_604 D4T, DDINoneK65R L34I, V35T, T39K, K43E, S68G, K122E, D123S, F124L, K173T, Q174K, D177E, I178M, Q207A, R211S, V245ECRF01_AE
 TH_717TH_717AY901935AZT, DDINoneM41L, K65R, Q151M V35T, T39K, K43E, V60I, S68G, T69I, K122E, D123S, I142V, K166R, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245ECRF01_AE
Ferradini (2011)40739RTHM026345TDF, 3TCNoneK65R, K70~, V75M, K219RK103N, Y181CV35T, T39D, S68N, T69N, K122E, D123S, I135T, K173L, Q174K, D177E, T200A, Q207S, R211S, L228R, K238RCRF01_AE