<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation E44D
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 2
Patients 13
Isolates 13
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Ariyoshi (2003)JPN35JPN35AY901418AZT, 3TC, D4TNoneM41L, D67DN, T69AD, M184V, L210LW, T215F E6D, K20R, V35T, E36ED, T39R, K43E, E44D, K102MR, K104R, K122E, D123S, S162Y, K173T, Q174K, D177E, Q207A, R211S, K238R, V245KCRF01_AE
 JPN25JPN25AY901426AZT, DDI, 3TC, D4TNoneM41L, D67N, L210W, T215YA98GE6D, K11T, V35T, T39K, K43E, E44D, V118I, D123N, I135T, K173I, Q174K, D177E, T200K, K201I, E204EV, Q207A, H208Y, R211N, K238R, V245ECRF01_AE
Non-B Workgroup (2005)TH_128TH_128AY605550AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, E44D, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, G196E, R206K, Q207A, R211D, K238R, V245ECRF01_AE
 TH_165TH_165AY605579AZT, DDINoneM41L, D67N, T69D, L210W, T215Y G18R, P19T, V35T, T39K, K43E, E44D, V60I, V118I, K122E, D123S, I135V, S162C, K173I, Q174K, D177E, T200I, Q207A, R211N, K238R, I244V, V245E, I257R, Q258PCRF01_AE
 TH_195TH_195AY605600AZT, DDINoneM41L, D67N, K70R, T215F, K219Q E28D, E29D, V35T, T39K, K43E, E44D, T69A, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, E224D, M230ICRF01_AE
 TH_197TH_197AY605602AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, E44D, V60I, V118I, K122E, D123S, S162N, K173I, Q174K, D177K, I178M, Q207A, R211N, K238RCRF01_AE
 TH_474TH_474AY901853D4T, DDINoneM41L, D67N, T69D, K70R, V75L, L210W, T215Y V35T, T39K, K43E, E44D, V60I, V118I, K122E, D123S, K173I, Q174K, D177E, Q207A, H208Y, R211N, V245KCRF01_AE
 TH_477TH_477AY901855DDC, AZTNoneM41L, T69D, L210W, T215YK238TV35T, T39K, K43E, E44D, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, S191C, G196E, T200A, Q207A, R211S, V245ECRF01_AE
 TH_587TH_587 AZT, 3TCNoneM41L, D67N, M184V, L210W, T215Y V35T, T39K, K43E, E44D, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211D, K238R, V245ECRF01_AE
 TH_601TH_601AY901891AZT, 3TCNoneM41L, D67N, L210W, T215YV179DV35T, T39K, K43E, E44D, V111I, V118I, K122E, D123S, K166R, K173I, Q174K, I178L, T200A, E204D, Q207A, R211S, V245ECRF01_AE
 TH_655TH_655AY901918AZT, DDINoneM41L, D67N, T69D, L210W, T215Y V35T, E44D, V118I, K122E, D123N, I135T, I142V, K173T, Q174K, D177E, I178M, T200I, Q207A, R211S, V245ECRF01_AE
 TH_718TH_718AY901936AZT, DDINoneM41L, D67N, T69D, L210W, T215Y V35T, T39K, K43E, E44D, V60I, K102Q, V118I, K122E, D123S, S162Y, E169D, Q174E, D177E, I178L, G196E, T200E, K201R, E204K, Q207A, R211D, K238R, V245ECRF01_AE
 TH_408TH_408 AZT, D4T, DDINoneM41L, D67E, V75M, L210W, T215Y V35T, T39K, K43E, E44D, V60I, S68G, V118I, K122E, D123N, K166R, K173L, Q174K, D177E, I178M, Q207A, R211N, V245ECRF01_AE