<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation T215Y
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 7
Patients 73
Isolates 73
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Ariyoshi (2003)JPN13JPN13A AZT, DDINoneM41L, D67N, T69D, K70R, T215Y, K219Q E6D, K11T, V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, V179I, G196GE, T200I, E204Q, Q207A, R211S, L228H, K238R, V245ECRF01_AE
 JPN15JPN15AY901416AZT, DDI, DDC, 3TC, D4TNoneM41L, D67N, V75M, M184V, L210W, T215Y, K219N E6N, K11T, V35T, T39K, K43E, V60I, V118VI, K122E, D123S, I135T, K173IV, Q174K, D177E, G196GE, Q207A, R211S, K238R, V245ECRF01_AE
 JPN38JPN38AY901419AZT, DDI, 3TCNoneM41L, D67N, L210W, T215Y E6D, V8I, K11T, V35T, T39K, K43E, R78RI, V118VI, K122E, D123S, K173I, Q174K, D177E, V179I, Q207A, R211S, K238R, V245ECRF01_AE
 JPN25JPN25AY901426AZT, DDI, 3TC, D4TNoneM41L, D67N, L210W, T215YA98GE6D, K11T, V35T, T39K, K43E, E44D, V118I, D123N, I135T, K173I, Q174K, D177E, T200K, K201I, E204EV, Q207A, H208Y, R211N, K238R, V245ECRF01_AE
Montes (2004)MB_patMOU00_MOUL723AJ577956AZT, DDI, D4T, 3TCNoneD67N, K70S, M184V, T215Y K11T, V35T, E36A, T39K, K43E, D121H, K122E, D123S, I135T, I142V, S162Y, F171Y, K173S, D177E, V179I, T200A, Q207ACRF01_AE
Hsu (2005)BAA148360BAA148360AY870145AZT, 3TC, D4TNoneM41L, D67DN, M184V, T215Y E6D, K11KT, V35T, T39K, K43E, K122E, D123S, I135IV, S162SDGN, K173I, Q174K, D177E, Q207A, R211S, K238KR, V245E, K277R, T286A, I293V, E312T, V317VA, I326LV, I329V, G335D, F346FY, M357Q, G359S, K366KR, A371V, I382IV, K390R, K395R, E399EDCRF01_AE
 BAA148361BAA148361AY870146D4T, 3TC, DDINoneM184V, T215Y E6D, K11T, K20R, V35T, T39K, K43E, V60I, S68G, V106I, K122E, D123N, I135T, K173I, Q174K, D177E, I178L, T200A, Q207A, R211S, I244V, V245E, A272P, T286TA, E291D, V292I, I293V, P294Q, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, T369A, A371V, K390R, K395RCRF01_AE
 BAA150613BAA150613AY870154AZT, 3TC, D4T, ABCNoneM41ML, L74V, Y115F, M184V, T215Y E6D, K11T, V35T, T39K, K43E, V111VI, K122E, D123S, T139K, K173I, Q174K, D177E, Q207A, R211S, F214L, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, R358RG, G359S, D364DE, K366R, A371V, K390R, Q394QH, K395RCRF01_AE
 BAA150617BAA150617AY870156D4T, DDI, AZT, 3TCNoneM41L, D67DN, M184V, T215Y E6D, K11T, V35T, T39K, K43E, K104R, K122E, D123S, I135IATV, I142V, K173IT, Q174K, D177E, Q207A, L210F, R211S, D218DE, K238R, V245E, T286A, A288AT, I293V, E312T, I326V, I329V, G335D, R356K, M357K, G359S, K366R, A371V, K390R, K395RCRF01_AE
 BAA154764BAA154764AY870165AZT, 3TC, D4T, DDINoneM41L, D67N, L210W, T215Y E6D, V35IT, T39K, K43E, E44A, V111I, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, T200TI, Q207A, H208Y, R211RK, K238R, V245E, A272P, E291D, I293V, E312A, I329V, G335D, M357K, R358RG, G359S, K366R, A371V, A376V, K390R, K395RCRF01_AE
 BAA157679BAA157679AY870184AZT, 3TCNoneM41L, D67N, M184V, L210W, T215Y, N348IT E6D, V21I, V35T, T39K, K43E, V60I, V106VI, V118VI, K122E, D123N, K173I, Q174K, D177E, I178M, G196E, Q207A, R211S, V245K, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, E399DCRF01_AE
 BAA161420BAA161420AY870227D4T, 3TC, DDINoneD67N, K70R, T215Y, N348NIY181C, G190AE6D, V35T, T39K, K43E, K122E, D123S, I135T, E138EQ, K173I, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395KRCRF01_AE
Non-B Workgroup (2005)TH_128TH_128AY605550AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, E44D, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, G196E, R206K, Q207A, R211D, K238R, V245ECRF01_AE
 TH_143TH_143AY605556AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, V60I, T69A, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I202V, Q207A, R211S, I244V, V245E, K249ECRF01_AE
 TH_153TH_153AY605565AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, V60I, V118I, K122E, D123S, K173L, Q174K, D177E, I178M, Q207A, R211D, K238R, V245ECRF01_AE
 TH_160TH_160AY605573AZT, 3TCNoneT215Y K20Q, V35T, T39K, K43E, V60I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, V245E, D256V, I257A, Q258PCRF01_AE
 TH_163TH_163AY605577AZT, DDINoneD67N, K70R, T215Y P19T, V35T, T39K, K43E, K122E, D123S, K173T, Q174K, D177E, T200I, Q207A, R211S, K238R, V245E, D256ECRF01_AE
 TH_165TH_165AY605579AZT, DDINoneM41L, D67N, T69D, L210W, T215Y G18R, P19T, V35T, T39K, K43E, E44D, V60I, V118I, K122E, D123S, I135V, S162C, K173I, Q174K, D177E, T200I, Q207A, R211N, K238R, I244V, V245E, I257R, Q258PCRF01_AE
 TH_166TH_166AY605580AZT, DDINoneM41L, D67N, K70R, T215Y, K219Q V35T, T39K, K43E, V60I, V90I, K122E, D123N, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, D250RCRF01_AE
 TH_180TH_180AY605589D4T, DDINoneM41L, D67N, T215Y K20R, E28D, V35T, T39K, K43E, K122E, D123S, S162C, K173I, Q174K, D177E, I178L, T200I, Q207A, R211S, V245ECRF01_AE
 TH_185TH_185AY605593AZT, DDINoneM41L, D67N, M184I, L210W, T215Y K20R, V35T, T39K, K43E, E44A, V60I, V118I, K122E, D123S, K173I, Q174K, D177E, G196E, Q207A, R211N, V245ECRF01_AE
 TH_197TH_197AY605602AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, E44D, V60I, V118I, K122E, D123S, S162N, K173I, Q174K, D177K, I178M, Q207A, R211N, K238RCRF01_AE
 TH_200TH_200AY605605AZT, DDINoneD67N, K70R, T215Y, K219Q V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, V179I, Q207A, R211S, K238R, V245E, I257R, Q258DCRF01_AE
 TH_212TH_212AY605615AZT, DDINoneM41L, D67N, L210W, T215Y Q23T, W24V, P25A, V35T, T39K, K43E, V60I, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211G, K238R, V245ECRF01_AE
 TH_218TH_218AY605621AZT, DDINoneM41L, T215Y V35T, T39K, K43E, K122E, D123S, I135V, T165A, K166R, K173A, Q174K, D177E, I178M, V179I, Q207A, R211S, V245KCRF01_AE
 TH_225TH_225AY605631D4T, 3TCNoneM41L, D67N, V75M, L210W, T215Y, K219Q P19T, V35T, T39K, K43E, V60I, K122E, D123N, K173T, Q174K, D177E, I178M, T200A, Q207A, R211N, K223Q, L228H, K238R, V245ECRF01_AE
 TH_230TH_230AY605636AZT, DDINoneM41L, D67N, L210W, T215Y M16W, D17L, V35T, T39K, K43E, E44A, V60I, V118I, K122E, D123S, K173T, Q174K, D177E, T200A, Q207A, H208F, R211K, K238R, V245ECRF01_AE
 TH_233TH_233AY605639AZT, D4T, DDINoneM41L, D67N, T69D, L210W, T215Y V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, Q207A, R211K, V245E, K249RCRF01_AE
 TH_239TH_239AY605645AZT, DDINoneM41L, L210W, T215Y, K219Q K20R, V35I, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, T200K, Q207A, R211S, K238R, V245ECRF01_AE
 TH_241TH_241AY605647AZT, DDINoneT215Y V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, Q207A, R211K, K238R, V245ECRF01_AE
 TH_242TH_242AY605648AZT, DDINoneM41L, L210W, T215Y V35T, T39K, K43E, S68G, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, E203D, Q207A, R211N, K220Q, V245E, E248DCRF01_AE
 TH_426TH_426AY901837AZT, 3TCNoneM41L, M184V, L210W, T215Y V35T, T39K, K43E, S68G, K122E, D123S, I135T, K173T, Q174K, T200A, E203D, Q207A, K238R, V245ECRF01_AE
 TH_429TH_429AY901838AZT, DDINoneM41L, D67E, L210W, T215Y V35T, T39K, K43E, E44I, S68G, V118I, K122E, D123S, I135T, S162A, T165I, K173I, Q174K, D177E, Q207A, R211N, L234HCRF01_AE
 TH_433TH_433AY901840D4T, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, K122E, D123T, Y127D, S162C, K173I, Q174K, D177E, T200A, E203Q, Q207D, K238RCRF01_AE
 TH_439TH_439AY901842D4T, DDINoneM41L, L74I, V75T, L210W, T215Y V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 TH_444TH_444AY9018443TC, D4TNoneT215Y V21I, V35T, T39K, K43E, T69S, V111I, K122E, D123S, S162C, I167V, K173I, Q174K, D177E, I178L, V179I, T200I, Q207A, R211T, K238R, V245ECRF01_AE
 TH_448TH_448AY901846D4T, DDINoneM41L, D67G, L74V, T215Y, K219NY181CV35T, T39K, K43E, E44A, S68G, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, K238R, V245ECRF01_AE
 TH_460TH_460AY901850AZT, DDINoneM41L, D67N, K70R, L210W, T215Y V35T, T39K, K43E, V60I, K104N, K122E, D123N, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211K, K238R, V245ECRF01_AE
 TH_473TH_473AY901852D4T, DDINoneM41L, D67E, L210W, T215Y V35T, T39R, K43E, S68G, V118I, K122E, D123N, K173A, Q174K, D177E, I178M, V179I, T200K, Q207A, R211N, V245DCRF01_AE
 TH_474TH_474AY901853D4T, DDINoneM41L, D67N, T69D, K70R, V75L, L210W, T215Y V35T, T39K, K43E, E44D, V60I, V118I, K122E, D123S, K173I, Q174K, D177E, Q207A, H208Y, R211N, V245KCRF01_AE
 TH_477TH_477AY901855DDC, AZTNoneM41L, T69D, L210W, T215YK238TV35T, T39K, K43E, E44D, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, S191C, G196E, T200A, Q207A, R211S, V245ECRF01_AE
 TH_483TH_483AY901857AZT, DDINoneT215Y V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, V245ECRF01_AE
 TH_494TH_494 AZT, DDINoneM41L, D67N, T215Y V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 TH_534TH_534AY901872D4T, DDINoneM41L, T215Y V35T, T39K, K43E, V60I, S68G, W88C, K122E, D123S, I135T, K173I, Q174K, D177E, D186E, V189I, Q207A, R211S, V245ECRF01_AE
 TH_536TH_536 AZT, DDINoneT215Y V35T, T39K, K43E, K122E, D123N, K166R, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, W252X, D256NCRF01_AE
 TH_542TH_542 D4T, DDINoneD67N, T215Y, K219Q V35T, T39K, K43E, K102N, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245KCRF01_AE
 TH_561TH_561AY901879AZT, DDINoneM41L, D67N, L210W, T215YE138KK32I, V35T, T39K, K43E, V118I, K122E, D123S, S162Y, R172K, Q174E, D177E, I178V, Q207A, R211N, K238R, V245ECRF01_AE
 TH_579TH_579AY901882DDC, AZTNoneM41L, D67N, K70R, T215Y, K219Q V35T, T39K, K43E, V60I, K102Q, K122E, D123N, S163C, K173I, Q174K, D177E, I178M, Q207A, R211S, D218E, K238R, V245ECRF01_AE
 TH_587TH_587 AZT, 3TCNoneM41L, D67N, M184V, L210W, T215Y V35T, T39K, K43E, E44D, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211D, K238R, V245ECRF01_AE
 TH_591TH_591AY901884DDC, AZTNoneM41L, D67E, V75M, L210W, T215YA98GK20R, V35T, T39K, K43E, V60I, S68G, V118I, K122E, D123N, K173A, Q174K, D177E, Q207A, R211N, K238R, V245ECRF01_AE
 TH_593TH_593AY901886AZT, DDINoneM41L, D67N, T69D, L210W, T215Y V35T, T39K, K43E, V60I, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, E203D, Q207A, R211S, K238R, V245ECRF01_AE
 TH_594TH_594AY901887AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, V111I, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 TH_595TH_595AY901888AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, K122E, D123S, I135L, S162Y, R172K, K173M, Q174K, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
 TH_601TH_601AY901891AZT, 3TCNoneM41L, D67N, L210W, T215YV179DV35T, T39K, K43E, E44D, V111I, V118I, K122E, D123S, K166R, K173I, Q174K, I178L, T200A, E204D, Q207A, R211S, V245ECRF01_AE
 TH_618TH_618AY901895D4T, 3TCNoneM41L, D67N, K70R, M184I, L210W, T215Y, K219QA98GV35T, T39K, K43E, V60I, K102Q, V118I, D123N, K173I, Q174K, D177E, T200A, Q207A, H208Y, R211S, K238R, V245ECRF01_AE
 TH_623TH_623 AZT, DDINoneM41L, D67N, T215Y V35T, T39K, K43E, K122E, D123S, S162Y, K173T, Q174K, D177E, I178M, T200I, Q207A, R211S, V245ECRF01_AE
 TH_643TH_643AY901908AZT, DDINoneM41L, D67N, L210W, T215YA98GV35T, T39K, K43E, V60I, V118I, K122E, D123S, T139A, K173I, Q174K, D177E, I178M, Q207A, R211N, K238R, V245ECRF01_AE
 TH_655TH_655AY901918AZT, DDINoneM41L, D67N, T69D, L210W, T215Y V35T, E44D, V118I, K122E, D123N, I135T, I142V, K173T, Q174K, D177E, I178M, T200I, Q207A, R211S, V245ECRF01_AE
 TH_661TH_661AY901919DDC, AZTNoneM41L, L210W, T215Y K22R, V35T, T39K, K43E, V60I, K122E, D123S, I135V, K173I, Q174K, D177E, Q207A, R211S, V245ECRF01_AE
 TH_665TH_665AY901920AZT, 3TCNoneM41L, D67N, M184V, L210W, T215YA98GV35T, T39K, K43E, V118I, K122E, D123S, I135L, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, D237G, V245E, S251MCRF01_AE
 TH_693TH_693AY901925AZT, DDINoneM41L, D67E, L210W, T215Y V35T, T39K, K43E, E44A, S68G, K102Q, K122E, D123N, K173I, Q174K, I178M, T200A, Q207A, R211N, K238R, V245ECRF01_AE
 TH_694TH_694 D4T, DDINoneM41L, M184V, L210W, T215Y V35T, T39K, K43E, K122E, D123S, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, V245KCRF01_AE
 TH_696TH_696 AZT, DDINoneM41L, L210W, T215Y V35T, T39K, K43E, E44A, V60I, S68G, V118I, K122E, D123S, I142V, K166R, K173I, Q174K, D177E, I178M, T200A, Q207A, R211NCRF01_AE
 TH_709TH_709AY901933AZT, DDINoneM41L, D67N, T215Y, K219Q V35T, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, K238RCRF01_AE
 TH_711TH_711 D4T, DDINoneM41L, D67N, L74I, V75T, L210W, T215Y K32I, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, G196E, T200I, Q207A, R211N, K238R, V245ECRF01_AE
 TH_713TH_713 AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, V60I, V118I, K122E, D123S, I135V, K173I, Q174K, D177E, Q207A, R211S, V245ECRF01_AE
 TH_718TH_718AY901936AZT, DDINoneM41L, D67N, T69D, L210W, T215Y V35T, T39K, K43E, E44D, V60I, K102Q, V118I, K122E, D123S, S162Y, E169D, Q174E, D177E, I178L, G196E, T200E, K201R, E204K, Q207A, R211D, K238R, V245ECRF01_AE
 TH_727TH_727 AZT, DDINoneD67N, K70R, T215Y, K219E V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 TH_754TH_754AY901947AZT, DDINoneM41L, L210W, T215Y V35T, T39K, K43E, V118I, K122E, D123S, K173V, Q174K, D177E, I178M, V179I, T200I, Q207A, R211N, L228H, K238R, V245KCRF01_AE
 TH_408TH_408 AZT, D4T, DDINoneM41L, D67E, V75M, L210W, T215Y V35T, T39K, K43E, E44D, V60I, S68G, V118I, K122E, D123N, K166R, K173L, Q174K, D177E, I178M, Q207A, R211N, V245ECRF01_AE
Tee (2006)MYKL136403MYKL1364AY960877NRTI, AZT, 3TCNoneM41L, D67N, K70R, V75I, T215Y, K219QE138KV35T, T39E, K122E, D123S, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245ECRF01_AE
Rosen-Zvi (2008)3606p36-3 D4T, 3TC, ABC, AZT, TDFNoneD67DN, M184V, T215YK101KEE6D, E28EK, V35T, T39K, K43E, K49R, D123E, E169D, K173A, Q174K, D177E, T200A, Q207A, R211RS, K238R, V245E, A272P, L283I, T286A, E291D, V292I, I293V, E312T, S322A, I326VCRF01_AE
Khairunisa (2014)TD10TD10KM212836TDF, AZT, 3TCNoneM41L, L74V, M184V, L210W, T215YK101E, V108I, Y181C, G190A, M230LE6D, K11T, V35T, T39N, K43Q, T69N, V118I, K122E, D123S, I135V, E138Q, S162C, R172K, K173I, Q174K, D177E, I178M, Q207A, R211S, H221Y, K223R, V245ECRF01_AE