<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation T215F
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 5
Patients 58
Isolates 58
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Ariyoshi (2003)JPN43JPN43BAY901410DDC, AZT, 3TC, D4TNoneD67G, K70R, M184V, T215F, K219E E6D, K11T, V35T, T39K, M41X, V60I, S68G, K122E, D123S, I135IT, K173T, Q174K, D177E, I178M, V179VI, Q207A, R211S, V245KCRF01_AE
 JPN28JPN28 AZT, 3TC, D4TNoneM41L, M184V, L210LW, T215F E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, K173I, Q174K, D177E, I178IM, V179VI, Q207A, R211S, K238R, V245ECRF01_AE
 JPN12JPN12BAY901413AZT, DDI, 3TC, D4TNoneM41L, D67N, K70R, V75M, M184V, T215F, K219Q K20R, V35T, T39K, K43E, V60I, K64H, T69N, D121H, K122E, D123S, S162SDGN, I167V, K173I, Q174K, D177E, T200I, Q207A, R211S, D218E, L228H, K238RCRF01_AE
 JPN13JPN13BAY901414AZT, DDINoneM41L, D67N, T69D, K70R, T215F, K219Q V35T, T39K, K43E, V60I, S105ST, K122E, D123S, K173M, Q174K, D177E, V179I, G196E, T200I, E204Q, Q207A, R211S, L228H, K238RCRF01_AE
 JPN35JPN35AY901418AZT, 3TC, D4TNoneM41L, D67DN, T69AD, M184V, L210LW, T215F E6D, K20R, V35T, E36ED, T39R, K43E, E44D, K102MR, K104R, K122E, D123S, S162Y, K173T, Q174K, D177E, Q207A, R211S, K238R, V245KCRF01_AE
 JPN1JPN1 AZT, DDCNoneD67N, K70R, T215F E6D, K11T, V35P, T39K, K43E, K104N, K122E, D123S, I135T, K173R, Q174K, D177E, I178M, V179I, Q207A, R211SCRF01_AE
Hsu (2005)BAA154762BAA154762AY870163D4T, DDI, AZT, 3TCNoneT215F E6D, K11KT, V35T, T39K, K43E, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200EK, Q207A, R211S, K238R, V245E, T286A, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K395RCRF01_AE
 BAA154770BAA154770AY870168D4T, DDI, AZT, 3TCNoneD67N, T215F E6D, V35T, T39K, K43E, T69S, V106VI, I135IT, S162SN, Q174D, D177E, I178V, V179I, T200I, I202V, E204K, Q207A, R211S, D218DE, V245E, K275KQ, T286A, A288T, E291ED, V292I, I293V, E312T, I329V, G335D, Y342F, M357K, G359S, K366R, T369A, A371V, K390R, K395RCRF01_AE
 BAA161451BAA161451AY870244D4T, DDINoneD67N, K70R, V75M, M184V, T215F, K219W E6D, V35T, E36D, T39K, K43E, V60I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, G196E, Q207A, R211K, K238R, V245EK, T286A, A288KR, E291D, V292I, I293V, E312T, P321S, I326V, I329V, G335D, M357R, G359S, K366R, A371V, T386I, K390R, K395R, E399DCRF01_AE
Non-B Workgroup (2005)TH_124TH_124AY605547D4T, DDINoneM41L, T215F G18P, P19D, K20Q, V35T, T39K, K43E, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, V254A, N255RCRF01_AE
 TH_127TH_127AY605549AZT, 3TCNoneM41L, D67N, K70R, L74I, T215F, K219Q V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245K, D256ECRF01_AE
 TH_130TH_130AY605553AZT, 3TCNoneD67N, T69D, K70R, L74I, T215F, K219Q V35T, T39K, K43E, V60I, K122E, D123S, K173T, Q174K, D177E, I178M, Q207A, R211S, K238R, V245KCRF01_AE
 TH_148TH_148AY605561AZT, DDINoneD67N, K70R, T215F, K219Q V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V245ECRF01_AE
 TH_150TH_150AY605564AZT, D4T, DDINoneD67N, K70R, L74I, T215F, K219Q P25A, V35T, T39K, K43E, K64H, T69N, V90I, D123N, R172K, K173I, Q174K, D177E, I178M, Q207A, R211S, D218E, V245KCRF01_AE
 TH_156TH_156AY605569AZT, D4T, DDINoneT215FY188DD17G, G18R, P19T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, E203K, Q207G, R211S, K238R, V245E, D256I, I257TCRF01_AE
 TH_157TH_157AY605570AZT, DDINoneM41L, D67N, K70R, L210W, T215F, K219Q D17G, G18R, K20R, V35T, T39K, K43E, E53D, V60I, L92M, V118I, K122E, D123S, S162Y, K173I, Q174K, D177E, I178M, Q207A, R211S, D218E, L228H, K238R, V245E, V254ACRF01_AE
 TH_169TH_169AY605583AZT, DDINoneD67N, K70R, T215F, K219Q V35T, T39K, K43E, D76H, G93R, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245QCRF01_AE
 TH_170TH_170AY6055843TC, D4TNoneM41L, D67N, K70R, M184I, T215F, K219Q G18W, P19T, L34I, V35T, T39K, K43E, V60I, T69N, K122E, D123N, S162A, K173I, Q174K, D177E, E203K, Q207A, R211S, K223E, K238R, V245ECRF01_AE
 TH_173TH_173AY605586AZT, DDINoneM41L, D67N, K70R, V75M, L210W, T215F, K219Q K20R, V35T, T39K, K43E, V60I, K122E, D123S, I135L, S162D, R172K, K173I, Q174K, D177E, I178M, Q207A, R211K, D218E, L228H, V245ECRF01_AE
 TH_178TH_178AY605588AZT, DDINoneM41L, T215F P19X, V35T, T39K, K43E, D123N, K173R, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V245ECRF01_AE
 TH_192TH_192AY605597AZT, 3TCNoneD67N, K70R, M184V, T215F, K219Q V35T, T39K, K43E, K49R, K122E, D123S, S162D, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 TH_195TH_195AY605600AZT, DDINoneM41L, D67N, K70R, T215F, K219Q E28D, E29D, V35T, T39K, K43E, E44D, T69A, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, E224D, M230ICRF01_AE
 TH_206TH_206AY605610AZT, DDINoneM41L, D67N, K70R, L210W, T215F, K219Q V35T, T39K, K43E, V60I, K122E, D123S, S162A, K173I, Q174K, D177E, I178M, Q207A, R211N, D218E, L228H, K238R, V245E, S251TCRF01_AE
 TH_207TH_207AY605611AZT, DDINoneM41L, D67N, K70R, L210W, T215F, K219Q D17G, G18W, P19T, V35T, T39K, K43E, V60I, V118I, K122E, D123S, R172K, K173I, Q174K, D177E, I178M, G196E, Q207K, R211S, D218E, V245KCRF01_AE
 TH_213TH_213AY605616AZT, DDINoneD67N, K70R, T215F, K219Q V35T, T39K, K43E, T69N, K122E, D123S, I159L, K173I, Q174K, D177E, V179I, G196E, T200A, Q207A, R211S, K238RCRF01_AE
 TH_215TH_215AY605618AZT, DDINoneD67N, K70R, T215F, K219Q V35T, T39K, K43E, K104N, D121H, K122E, D123S, I135V, S162A, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 TH_217TH_217AY605620AZT, DDINoneM41L, D67E, T215F V35T, T39K, K43E, V60I, S68G, W88C, K122E, D123S, K173A, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 TH_430TH_430AY901839AZT, DDINoneD67N, K70R, T215F, K219Q K20R, V35T, T39K, K43E, V60I, T69N, K122E, D123S, Y127D, K173I, Q174K, D177G, Q207A, R211S, K238R, V245ECRF01_AE
 TH_463TH_463 AZT, DDINoneT215F, K219Q V35T, T39Q, K43E, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, P243H, V245ECRF01_AE
 TH_487TH_487AY901858AZT, DDINoneT215F, K219Q K22R, V35T, T39K, K43E, V60I, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, E194D, Q207A, R211S, F214L, K238R, V245ECRF01_AE
 TH_515TH_515AY901865D4T, DDINoneD67N, K70R, L74I, T215F, K219Q V35T, T39E, V60I, K122E, D123N, I135T, S162A, K173I, Q174K, D177E, I178M, G196E, Q207A, R211S, K238R, V245ECRF01_AE
 TH_526TH_526AY901868AZT, DDINoneD67N, K70R, T215F V35T, T39K, K43E, N81T, V111M, K122E, D123N, Y146V, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, V245ECRF01_AE
 TH_529TH_529AY901871AZT, DDINoneM41L, D67N, L210W, T215FF227LV35T, T39K, K43E, N57Y, V60I, V118I, K122E, D123S, I135T, K173I, Q174K, I178M, T200I, Q207A, R211S, L228P, V245ECRF01_AE
 TH_543TH_543 AZT, DDINoneD67N, T215F, K219Q V35T, T39K, K43E, K64N, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, E203G, Q207A, R211S, D218E, K238R, V245E, E248DCRF01_AE
 TH_547TH_547AY901873AZT, DDINoneT215FV179EV35T, T39K, K43E, K122E, D123N, I135T, K173I, Q174K, D177E, Q207A, R211S, V245ECRF01_AE
 TH_551TH_551AY901875AZT, 3TC, DDINoneM41L, D67N, K70R, M184V, T215F, K219EA98GK20R, K22R, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, T200A, E203K, Q207A, R211S, L228H, V245K, K249Q, D250YCRF01_AE
 TH_552TH_552AY901876AZT, DDINoneD67N, T69D, K70R, T215F, K219Q V35T, T39K, K43E, G45R, D121H, K122E, D123S, I135L, S162C, R172K, K173I, Q174K, D177E, I178L, Q207A, R211S, K238RCRF01_AE
 TH_583TH_583AY901883AZT, 3TC, DDINoneM41L, D67N, K70R, M184V, T215F, K219E V35T, T39K, K43E, V60I, K102M, K122E, D123S, I135T, K173T, Q174K, I178M, G196E, T200I, E203K, Q207A, R211N, K238R, V245KCRF01_AE
 TH_614TH_614AY901894AZT, DDINoneD67N, K70R, T215F, K219Q V35T, T39K, K43E, K122E, D123S, Y146S, K173I, Q174K, D177E, I178M, G196E, Q197R, T200A, K238RCRF01_AE
 TH_619TH_619AY901896AZT, DDINoneM41L, T215F V35T, T39E, S68G, R78K, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, S191Y, Q207A, R211S, V245ECRF01_AE
 TH_627TH_627 AZT, DDINoneD67N, T215F V35T, T39K, K43E, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, G196A, Q207A, R211S, V245ECRF01_AE
 TH_630TH_630AY901901AZT, 3TCNoneD67N, K70R, T215F, K219Q K20R, V35T, T39K, K43E, K122E, D123S, K126R, N136T, K173S, Q174K, N175I, D177E, I178M, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 TH_632TH_632AY901902DDC, AZTNoneD67N, K70R, T215F, K219Q E28K, K32E, V35T, T39K, V60I, K122E, D123S, K173I, Q174K, D177E, V179T, Q207A, R211S, K238R, V245ECRF01_AE
 TH_637TH_637AY901905AZT, DDINoneD67N, K70R, T215F, K219Q V35T, T39K, K43E, V106I, K122E, D123N, K173V, Q174K, D177E, V179I, Q207A, R211S, K238R, V245KCRF01_AE
 TH_638TH_638AY901906AZT, DDINoneD67N, K70R, T215F, K219Q V35T, T39K, K43E, V90I, K122E, D123S, K173I, Q174K, D177E, I178M, G196E, T200I, E203D, Q207A, R211K, K238R, V245KCRF01_AE
 TH_645TH_645AY901909AZT, DDINoneD67N, L74I, T215F, K219QA98GV35T, T39K, K43E, T69N, K122E, D123S, K173I, Q174K, D177E, V179I, T200I, I202V, Q207A, R211S, K238RCRF01_AE
 TH_646TH_646AY901910AZT, DDINoneT215F V35T, T39K, K43E, S105A, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, I202V, Q207A, R211S, V245ECRF01_AE
 TH_656TH_656 D4T, DDINoneD67N, L210W, T215F V35T, T39K, K43E, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
 TH_699TH_699 AZT, DDINoneD67N, K70R, T215F, K219Q K20R, V35T, T39K, K43E, K122E, D123S, S162Y, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245ECRF01_AE
 TH_748TH_748 AZT, 3TCNoneD67N, T215F, K219Q V35T, T39K, K43E, V60I, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, Q207A, R211S, V245ECRF01_AE
 TH_750TH_750 AZT, 3TCNoneT215F V35T, T39K, K43E, K122E, D123S, S162N, K173I, Q174K, D177E, I178M, Q207A, R211S, V245ECRF01_AE
 TH_766TH_766AY901949AZT, DDINoneK70R, T215F, K219Q V35T, T39K, K43A, S68I, A98E, K122E, D123S, I142V, K173I, Q174K, D177E, I178M, T200I, I202V, Q207A, R211S, K238R, V245KCRF01_AE
 TH_779TH_779AY901955AZT, 3TCNoneM41L, D67N, K70R, M184V, T215F, K219Q V35T, T39K, K43Q, A98S, K122E, D123S, K173I, Q174K, D177E, T200A, I202V, Q207A, R211S, D218E, V245ECRF01_AE
 TH_414TH_414 AZT, DDINoneD67N, T69D, K70R, T215F, K219Q K20R, V35T, T39E, V60I, K122E, D123S, I135V, S162C, K173I, Q174K, D177E, I178M, T200I, E203D, Q207A, R211K, L228H, K238R, V245ECRF01_AE
 TH_415TH_415 AZT, DDINoneD67N, K70R, T215F, K219Q V35T, T39K, K43E, K122E, D123S, I135L, R172K, K173M, Q174K, D177E, I178M, G196E, T200I, Q207A, R211K, L228R, K238R, V245ECRF01_AE
 TH_416TH_415 DDC, AZTNoneM41L, D67N, T215F V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, R211S, K238RCRF01_AE
Tee (2006)MYKL148203MYKL1482AY960889NRTI, D4T, DDINoneM184V, T215FA98GK20R, V35T, T39K, K43E, S68G, K122E, D123S, I135V, K166R, K173I, Q174K, D177E, Q207T, L210M, R211S, F214L, K238R, V245ECRF01_AE
Rosen-Zvi (2008)8207p82-2 AZT, 3TC, ABCNoneM184V, T215F E6D, V8I, K11T, V35T, T39K, K122E, D123S, I178M, T200A, Q207A, R211S, V245E, E291A, E312T, I326V, I329VCRF01_AE