<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation L210M
Rx RTI-naive
IncludeMixtures No
References 29
Patients 69
Isolates 70
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Lan (2003)NTHvr131NTHvr131AY238042NoneNone  E6D, K11T, K20R, V35I, T39K, K43E, V111X, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, L210M, R211S, F214L, K238R, V245ECRF01_AE
Hsu (2005)LYH_AY870223BAA161413AY870223NoneNone  E6D, V35T, T39K, K43E, S68G, K122E, D123S, I135T, K173M, Q174K, D177E, I178L, T200A, Q207A, L210M, R211S, V245E, V276I, T286A, V292I, I293V, E312T, I326V, I329V, G335D, K350R, M357K, G359S, K366R, A371V, A376V, K390R, K395RCRF01_AE
Ly (2005)NL_KHM_CD18KHM_CD18DQ013443NoneNone  K20R, V35T, E36D, T39K, K43E, K122E, D123N, T139S, S162C, K173T, Q174K, D177E, I178M, E194D, Q207N, L210M, R211K, K238R, V245ECRF01_AE
Tee (2005)03MYKL155503_1555AY904655NoneNone  V35T, T39K, K43E, K122E, D123N, K173I, Q174K, D177E, I178M, I202V, Q207A, L210M, R211N, V245ECRF01_AE
 04MYKL173404_1734AY904684NoneNone  T27P, V35T, T39K, K43E, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, T200A, I202V, Q207A, L210M, R211S, K238R, V245ECRF01_AE
Chang (2008)TW5407aTW5407a NoneNone  E6D, K20R, V21I, V35T, T39K, K43E, V60I, K122E, D123S, I135T, K173I, Q174K, D177E, V179I, I202V, Q207A, L210M, R211S, K238R, V245ECRF01_AE
Sirivichayakul (2008)BED-49BED-49RTJQ364383NoneNone  V35T, T39K, K43E, K102E, K122E, D123N, K173I, Q174K, D177E, V179T, I202V, Q207A, L210M, R211S, F214L, D237E, I244D, V245ECRF01_AE
Auwanit (2009)135AE-RT135FJ463587NoneNone  E6D, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, T200A, Q207A, L210M, R211S, K238KR, V245HKNQCRF01_AE
 153AE-RT153FJ463590NoneNone  E6D, V35T, T39K, K43E, V60I, K122E, D123S, I135T, I142IV, K173I, Q174K, D177E, I178M, Q207A, L210M, R211S, V245ECRF01_AE
 162AE-RT162FJ463595NoneNone  E6D, K11T, V35T, T39K, K43E, V106I, K122E, D123S, S162C, K173T, Q174K, T200A, Q207ADNT, L210M, R211RKNS, K238R, V245E, K249RCRF01_AE
Ishizaki (2009)A2_441A2_441FJ007099NoneNone  E6D, V35T, T39N, K122E, D123S, I135T, I142V, S162C, K173I, Q174K, D177E, Q207N, L210M, R211S, K238R, V245ECRF01_AE
Nouhin (2009)KC21KC21RTFJ531893NoneNone  E40D, V111I, K122E, D123N, K166R, K173IT, Q174K, N175H, I178L, V179I, Q207A, L210M, R211N, K238RCRF01_AE
Tu (2009)49plasma49EU518339NoneNone  E6D, K11T, V35T, T39K, K43E, E89EK, S105SP, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I178M, Q207A, L210M, R211S, Q222QH, K238RCRF01_AE
Vercauteren (2009)pt19701448749787GQ399054NoneNone  E6D, K11A, V35T, T39K, K43Q, V60I, K122E, D123S, I142IV, A158AS, K166R, K173I, Q174K, D177E, Q207A, L210M, R211S, K238R, V245E, A272P, V292VI, I293V, P294AITV, K311KR, E312ADNT, I326V, I329VCRF01_AE
Han (2010)LN206LN206FJ531471NoneNone  E6D, K11T, V35T, T39K, K43E, K122E, D123S, S162C, K173S, Q174K, D177E, I178M, Q207A, L210M, R211S, K238R, V245ECRF01_AE
Phan (2010)ND08ND08AB519453NoneNone  E6D, K11T, K32E, V35T, T39K, K122E, D123S, I135K, S162C, K173I, Q174K, D177E, Q207S, L210M, R211SCRF01_AE
Bontell (2011)Pat03508.VL786UsHQ852881NoneNone  E6D, K11T, V35T, T39K, K43Q, H96E, A98T, K122E, D123S, I135IT, S162C, K173T, Q174K, D177E, I178M, T200TA, Q207N, L210M, R211SCRF01_AE
Lazaro (2011)DN-M12DN-M12HQ542755NoneNone  I5IN, E6NY, V35I, K122E, D123S, S162C, E169ED, K173IMRT, Q174K, D177E, G196E, E203ED, Q207A, L210M, R211S, K238R, V245ECRF01_AE
 DT-M1DT-M1HQ542784NoneNone  K30KE, V35T, T39K, K43E, K102Q, K122E, D123NS, S162C, F171Y, K173AGRT, Q174K, D177E, I178M, T200TI, Q207A, L210M, R211S, K238RCRF01_AE
Zeng (2011)K13K13JF505554NoneNone  E6D, K11T, V35T, T39K, K43E, K64R, D121H, K122E, D123S, S162C, K173S, Q174K, D177E, I178M, Q207A, L210M, R211S, K238RCRF01_AE
 K64K64JF505555NoneNone  E6D, K11T, V35T, T39K, K43E, K64R, K122E, D123S, S162C, K173S, Q174K, D177E, I178M, Q207A, L210M, R211S, K238RCRF01_AE
Chen (2012)YN10DH0080YN10DH0080JQ658701NoneNone  E6D, K11T, V35T, T39K, K43E, S68G, K122E, D123S, S162C, K173I, Q174K, D177E, Q207A, L210M, R211S, K238R, V245E, K249KR, A272P, E291D, V292I, I293VCRF01_AE
Chow (2012)10MYKJ06710MYKJ067JX390612NoneNone  E6D, P9S, V35T, K122E, D123S, S162C, K173R, Q174K, D177E, Q207A, L210M, R211N, V245E, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, R448K, L452LS, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, E529D, A534S, I556V, K558KRCRF01_AE
Rolland (2012)AA036a05LAA036a05LJX447114NoneNone  E6D, K11T, V35T, T39K, K43E, K64R, K122E, D123S, T165I, K173I, Q174K, D177E, I178M, T200A, Q207A, L210M, R211S, K238R, V245E, T286A, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, T377S, S379G, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, A502T, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
Telan (2012)1105274811052748AB747453NoneNone  E6D, V35I, E36A, T39K, K43E, V111I, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, L210M, R211S, K238R, V245ECRF01_AE
Yang (2012)GZ107GZ107JN848847NoneNone  I2V, E6D, K11T, K20R, V35T, T39K, K43E, V60I, S68G, V106I, K122E, D123N, T139A, I167IV, K173IT, Q174K, D177E, I178L, T200R, Q207A, L210M, R211S, K238R, V245E, T286A, E291D, V292I, I293VCRF01_AE
 GZ106GZ106JN848892NoneNone  I2V, E6D, K11T, K20R, V35T, T39K, K43E, V60I, S68G, V106I, K122E, D123N, T139A, K173I, Q174K, D177E, I178L, T200R, Q207A, L210M, R211S, K238R, V245E, T286A, E291D, V292I, I293VCRF01_AE
Zeng (2012)CN1295CN1295JQ028251NoneNone  E6D, K11T, V35T, T39N, K122E, D123K, S162C, K173I, Q174K, D177E, I178M, Q207S, L210M, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, N447S, D471E, Q480H, H483Y, L491S, A502V, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
Chow (2013)10MYKJ06710MYKJ067KC477992NoneNone  E6D, P9S, V35T, K122E, D123S, S162C, K173R, Q174K, D177E, Q207A, L210M, R211N, V245E, T286A, E291D, V292I, I293VCRF01_AE
 10MYKJ04110MYKJ041KC477969NoneNone  E6D, K122E, D123S, S162C, K173R, Q174K, D177E, Q207A, L210M, R211N, E233EG, K238R, V245E, A272P, K275Q, T286A, V292I, I293VCRF01_AE
Kiertiburanakul (2013)R74071R74071KC791290NoneNone  E6D, V35T, T39K, K43E, K122E, D123S, S162C, K173I, Q174K, D177E, I178IM, V179I, Q207A, L210M, R211S, K238R, V245NCRF01_AE
 X12001X12001KC994342NoneNone  E6D, V21I, L34LF, V35T, T39K, K43E, P52PA, V60I, T69TN, K102Q, S162C, K173I, Q174K, D177E, I178M, E194EK, T200A, Q207A, L210M, R211S, M230MR, K238R, V245E, E248EK, T286A, E291D, V292I, I293V, L310LF, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, T377TIM, S379SAGT, V381VI, K390R, E399D, A400T, T403TMCRF01_AE
 R75041R75041KC962532NoneNone  E6D, V8I, K11A, V35T, T39K, K43E, K122E, D123S, I135T, K173I, Q174K, I178M, G196E, I202IV, Q207A, L210M, R211S, V245E, K275R, V276I, T286A, E291D, V292I, I293V, P294PT, E297EK, E312T, I326V, I329F, Q330R, K331N, Q334PCRF01_AE
 R74146R74146KC791365NoneNone  E6D, K11S, V35T, T39K, K43E, V60I, K64R, K122E, D123S, I135T, K173I, Q174K, I178IM, Q197R, T200E, Q207A, L210M, R211S, V245E, E248DCRF01_AE
 R74185R74185KC791404NoneNoneT215TS E6D, D17DN, V35T, T39K, K43E, I50IV, S68G, K122E, D123N, S162C, K173I, Q174K, D177E, I178L, T200A, Q207A, L210M, R211RK, W239WR, V245ECRF01_AE
 R73091R73091KC810630NoneNone  E6D, K22R, V35T, T39K, K43E, S68G, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, L210M, R211S, K238R, V245ECRF01_AE
 R73227R73227KC810752NoneNone  E6D, K11T, V35T, T39K, K43E, D123S, K173I, Q174K, D177E, I178M, V179I, G196E, Q207A, L210M, R211S, K238R, V245ECRF01_AE
 R73028R73028KC810799NoneNone  V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, L210M, R211S, V245E, E248DCRF01_AE
 R74009R74009KC791229NoneNone  E6D, K11T, V35T, T39N, V60I, K122E, D123NS, I135T, I142V, S162ST, K166KR, K173I, Q174K, D177E, I178M, G196GE, T200TA, Q207A, L210M, R211S, K238R, V245ECRF01_AE
 R74152R74152KC791371NoneNone V179DE6D, K11T, K20R, V35T, T39EK, D86E, D123NS, K173I, Q174K, D177E, Q197P, T200A, Q207A, L210M, R211N, I244IV, V245ECRF01_AE
 R41044R41044KC970978NoneNone  E6D, V35T, T39K, K43E, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, T200I, Q207A, L210M, R211S, K238R, V245ECRF01_AE
 R73049R73049KC810591NoneNone  E6D, K11T, V35T, T39K, K43E, V111I, D121H, K122E, D123GS, K173IM, Q174K, D177E, I178M, V179I, I202V, Q207A, L210M, R211S, I244V, V245ECRF01_AE
 R73111R73111KC810649NoneNone  E6D, V35T, T39K, K43E, K122E, D123S, I135L, E138EG, R172K, K173I, Q174K, D177E, I178M, Q207A, L210M, R211S, K238R, V245ECRF01_AE
 X12052X12052KC994384NoneNone  E6D, K11A, V35T, T39K, K43E, K102KR, K122E, D123N, I135T, S162ST, K166KR, K173IM, Q174K, D177E, G196E, I202V, Q207A, L210M, R211S, V245E, I274IV, I293V, L303LF, E312T, I326V, I329V, G335D, R356K, M357K, R358RG, G359S, K366R, A371V, I375IV, T386I, K390R, K395R, E399GV, A400TCRF01_AE
 R73005R73005KC810812NoneNoneV75L V35T, T39K, K43A, K122E, D123S, F171Y, K173I, Q174K, D177E, I178M, T200I, Q207A, L210M, R211S, V245ECRF01_AE
 R74163R74163KC791382NoneNone  E6D, K11T, V35T, T39N, V60I, I63IM, D121Y, K122E, I142V, K173I, Q174K, D177E, I178M, T200I, Q207A, L210M, R211S, V245KCRF01_AE
 R71036R71036KC921903NoneNone  V35T, T39K, K43E, K122E, D123S, I142T, A158S, T165I, K173M, Q174K, I202V, Q207A, L210M, R211S, V245ECRF01_AE
 R72091R72091KC867630NoneNone V179DV35L, E36K, I37F, T39K, K43E, V60I, K64R, R83K, D86E, V90I, K122E, D123S, I135V, K173I, Q174K, D177E, I178M, I202V, Q207A, L210M, R211S, I244V, V245ECRF01_AE
 R41155R41155KC970893NoneNone  E6D, K11A, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, L210M, R211SCRF01_AE
 R73084R73084KC810624NoneNone  E6D, K11T, V35T, T39K, K43E, V60VI, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, Q207A, L210M, R211S, K238R, V245E, E248DCRF01_AE
 R12184R12184KC994310NoneNone  E6D, V35T, T39K, K43Q, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, Q207N, L210M, R211S, K238KR, V245E, T286A, E291D, V292I, I293V, E312TCRF01_AE
 R51061R51061KF059741NoneNone  E6D, D17G, G18CW, V35T, T39K, K43E, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, G196KR, T200A, Q207A, L210M, R211SCRF01_AE
 R74197R74197KC791415NoneNone  E6D, K11T, V35T, T39K, K43KE, S68G, K122E, D123S, I142IV, K173I, Q174K, D177E, I178M, T200A, Q207A, L210M, R211S, V245ECRF01_AE
 R74183R74183KC791402NoneNone  E6D, K11T, K30KQ, V35T, T39K, K43E, K122E, D123S, E138A, S162C, K173I, Q174K, I202V, Q207T, L210M, R211S, V245ECRF01_AE
 R74091R74091KC791310NoneNone  E6D, K11T, V35T, T39K, K43E, K101R, D121HY, K122E, D123DN, S162A, K173I, Q174K, D177E, Q207A, L210M, R211S, V245ECRF01_AE
 R73027R73027KC810806NoneNone  V35T, T39K, K43E, V106I, K122E, D123S, K173I, Q174K, D177E, I202V, Q207A, L210M, R211S, K238R, V245ECRF01_AE
 R73230R73230KC810755NoneNone  E6D, K11T, T27S, E28EA, V35T, T39K, K43E, K122E, D123S, I135T, I142IV, S162C, K173I, Q174K, D177E, I202V, Q207A, L210M, R211S, K238R, V245ECRF01_AE
 R74075R74075KC791294NoneNone K103NE6D, V35T, T39K, K43E, K122E, D123S, I135T, K166KR, K173I, Q174K, D177E, I178M, T200I, Q207A, L210M, R211S, K238R, V245E, E248DCRF01_AE
 R73223R73223KC810748NoneNone  E6D, K30KE, I31P, V35T, T39K, K43E, K122E, D123S, I142IV, K173I, Q174K, D177E, V179I, Q207A, L210M, R211S, K238R, V245ECRF01_AE
 R72194R72194KC857177NoneNone  T39K, K43E, V60I, W88C, V111I, V118I, D121H, K122E, D123S, K173IL, Q174N, Q207A, L210M, R211S, F214L, K238R, V245VECRF01_AE
 R72151R72151KC857140NoneNone  T39K, K43E, K122E, D123S, K173I, Q174K, Q207A, L210M, R211S, K238R, V245QCRF01_AE
 R72208R72208KC857190NoneNone  T39K, K43E, K64KR, K122E, D123S, I142IV, K166R, K173I, Q174K, D177E, I178M, T200TA, Q207A, L210M, R211S, V245KCRF01_AE
 R72247R72247KC857229NoneNoneM184VG190AT39K, K43E, K64KR, K122E, D123S, I135V, S162C, K173I, Q174K, D177E, I202V, Q207A, L210M, R211S, K238RCRF01_AE
Kijak (2013)05TH74145205TH741452JN248355NoneNoneN348IY181CK11T, V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, I178M, T200E, Q207A, L210M, R211K, D218E, K238R, V245Q, A272P, T286A, E291D, I293V, E312T, I326V, I329V, G335D, P345Q, M357R, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, L452Q, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, K530R, A534S, A554SCRF01_AE
Li (2013)28692869JQ901075NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200R, Q207A, L210M, R211S, F214L, K238R, V245D, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, F346Y, M357K, G359S, K366R, A371V, K390R, K395R, A400T, E432D, N447S, R448K, D460N, D471E, Q480H, H483Y, L491P, K512R, L517I, S519N, Q524E, I526V, A534S, A554SCRF01_AE
Li (2013)21812181JQ302660NoneNone  E6D, K11T, V35T, T39K, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200A, Q207S, L210M, R211S, V245E, E291D, V292I, I293V, E297EK, A304AE, E312T, I326V, I329V, G335D, R356RK, M357K, G359S, K366R, A371V, I375V, A400T, T403M, E432D, N447S, D460N, D471E, Q480H, H483L, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
Wu (2013)HFP112HFP112KC203313NoneNone  E6D, V35T, T39K, K43E, S105A, K122E, D123N, S162C, Q174K, D177E, I195IV, Q207A, L210M, R211S, K238R, V245ECRF01_AE
Zeng (2013)cdbc65cdbc65KC352137NoneNone  E6N, K11T, V35T, T39K, K43E, K122E, D123S, S162C, K173R, Q174N, D177E, Q207A, L210M, R211S, K238RCRF01_AE
 cdbc63cdbc63KC352135NoneNone  E6D, V35T, T39G, V118I, K122E, D123S, K173T, Q174K, D177E, V179T, G196E, T200A, Q207A, L210M, R211S, F214LCRF01_AE
 cdbc61cdbc61KC352133NoneNone  E6D, K11T, V35T, T39K, K43E, S105A, K122E, D123S, K173R, Q174K, D177E, I178M, V179I, I202V, Q207A, L210M, R211SCRF01_AE