<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation V118I
Rx RTI-naive
IncludeMixtures No
References 26
Patients 95
Isolates 95
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Tee (2005)04MYKL176804_1768AY904688NoneNone  V35T, T39K, K43E, V60I, V106I, V118I, K122E, D123N, S162C, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
Gatanaga (2007)C04-51110160-1C04-51110160-1AB640260NoneNone  E36D, T39K, K43E, V118I, K122E, D123S, I135R, T165I, K173T, Q174K, D177E, I202V, Q207A, R211SCRF01_AE
Chang (2008)TW10065TW10065EU164867NoneNoneK65KN E6ED, K11T, V35T, T39K, M41MV, K43E, V106I, V118I, K122E, D123N, S162C, Q174E, D177DE, V179I, T200A, E204K, Q207A, R211S, K238R, V245ECRF01_AE
 TW1253TW1253EU164881NoneNone  E6D, K11T, V35IT, T39K, K43E, V106I, G112A, V118I, K122E, D123S, S162C, Q174K, D177E, V179I, T200I, Q207A, R211N, K238R, V245QCRF01_AE
Nguyen (2008)041VN041 NoneNone  V35L, E36N, I37X, T39EK, K43KQ, V106I, V118I, D123N, S162C, K173IT, Q174K, D177E, I178M, Q207S, R211S, V245ECRF01_AE
Auwanit (2009)161AE-RT161FJ463594NoneNone  E6D, V35T, T39K, K43E, V106I, V118I, K122E, D123S, S162C, K173I, Q174K, D177E, V179I, T200A, Q207A, R211S, K238R, I244V, V245ECRF01_AE
Ayouba (2009)FD0440FD0440RTGQ352008NoneNone  V35T, T39K, K43E, T107TS, V118I, K122E, D123S, S162C, K173A, Q174K, D177E, T200I, Q207A, R211S, K238KR, V245ECRF01_AE
Ishizaki (2009)A2_395A2_395FJ007084NoneNone  E6D, K11T, V35T, T39Q, V106I, T107S, V118I, K122E, D123S, S162C, K173I, Q174K, D177E, V179I, T200A, Q207S, R211S, K238R, V245ECRF01_AE
Liao (2009)VNAG20697VNAG206FJ185248NoneNone  E6D, K11T, V35T, T39K, K43E, K102R, V118I, D121H, K122E, D123S, I142V, K173I, Q174K, D177E, V179I, T200I, Q207A, R211N, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, D471E, H483Q, L491S, K512R, L517V, Q524E, K530R, A534S, A554SCRF01_AE
Vercauteren (2009)pt9907326852698GQ400034NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, S162N, K173I, Q174K, D177E, I178M, T200E, Q207A, R211S, V245E, A272P, T286A, E291D, V292I, K311R, E312T, I326V, I329VCRF01_AE
 pt97uzTZcDw0JoGQ400927NoneNone  E6D, V35T, T39K, K43E, V60I, S68G, V118I, K122E, D123S, I135T, K166R, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293VCRF01_AE
 pt48XKy3Xx0wv4GQ400976NoneNone  I5IN, E6D, V35T, T39K, K43E, V106I, V118I, K122E, D123S, I135R, S162C, K173I, Q174K, I178M, T200E, I202V, Q207A, R211SCRF01_AE
Han (2010)LN109LN109FJ531411NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245ECRF01_AE
 LN128LN128FJ531424NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, I135T, T165I, K173RT, Q174K, D177E, T200I, Q207A, F214L, K238R, V245E, V276ICRF01_AE
 LN157LN157FJ531455NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174N, D177E, T200R, Q207A, R211S, F214L, K238R, V245D, S251H, V276ICRF01_AE
 LN151LN151FJ531462NoneNone  E6D, K11T, V35T, T39K, K43E, K102R, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, V179I, T200I, Q207A, R211S, F214L, K238RCRF01_AE
 LN171LN171FJ531467NoneNone  E6D, K11T, V35T, T39K, K43E, K82R, V118I, D123N, I135T, K173I, Q174K, D177E, G196R, T200I, I202V, Q207A, R211S, F214L, K238R, V245K, V276ICRF01_AE
Hattori (2010)C08-504601C08-504601AB864607NoneNone  E6D, K11T, K22R, V35T, T39K, K43E, S68G, V118I, D123N, K173IV, Q174K, D177E, Q207A, R211SCRF01_AE
 F08-5112167F08-5112167AB866798NoneNone  E6D, K11T, V35IMT, T39E, V111I, V118I, D121H, K122E, D123S, T139A, K166KR, K173I, Q174K, D177E, T200E, Q207A, R211S, F214L, K238R, V245ECRF01_AE
 C08-51110753C08-51110753AB865160NoneNone  I5V, E6D, V35T, T39K, K43E, V106I, V118I, K122E, D123S, S162C, K173I, Q174K, D177E, I178M, T200A, Q207D, R211S, E224D, K238RCRF01_AE
Phan (2010)ND20ND20AB519627NoneNone  E6D, V35I, T39K, K43E, V118I, K122E, D123S, S162C, K173S, Q174K, D177E, I178M, Q207A, R211SCRF01_AE
Hamers (2011)CP076300882CP076300882HQ995135NoneNone  K11T, K20R, K32T, V35T, T39K, V60I, K64M, V118I, D123N, I135R, K173S, V179I, T200S, I202V, Q207A, R211S, F214L, V245Q, E248DN, A272P, T286A, E291D, V292I, I293V, P294TCRF01_AE
An (2012)09LNA02009LNA020JX960613NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200R, E203D, Q207A, R211S, F214L, K238R, V245D, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, K431R, E432D, N447S, R448K, D460N, D471E, Q480H, L491P, K512R, L517I, S519N, Q524E, I526V, A534S, A554S, K558RCRF01_AE
 09LNA00709LNA007JX960627NoneNone  E6D, V35T, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200V, Q207A, R211S, F214L, V245E, V276I, E291D, V292I, I293V, E312T, P321S, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, E404D, E432D, N447S, D460N, D471E, Q480H, H483Y, L491S, K512R, E514D, L517I, S519N, Q524E, I526V, A534S, A554SCRF01_AE
 10LNA01610LNA016JX960629NoneNone  P4H, E6D, K11T, V35T, T39K, K43E, K64R, V118I, K122E, D123S, I135T, K173G, Q174K, D177E, G196R, T200I, I202V, Q207A, R211S, F214L, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, E432D, N447S, D460N, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524E, I526V, A534S, A554SCRF01_AE
 10LNA05710LNA057JX960633NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, R356K, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, E432D, D460N, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, I526V, K530R, A534S, A554SCRF01_AE
Ssemwanga (2012)3445HR3445HRJF800199NoneNone  K11T, V35T, I50V, V118I, D123S, K173A, V179T, T200A, Q207A, R211S, F214LCRF01_AE
Yang (2012)37553755JQ617231NoneNone  E6D, V35T, T39K, K43E, S68G, V118I, K122E, D123S, I135AT, I142IV, S162SC, K173I, Q174KN, D177E, I178IM, T200IL, Q207A, R211S, K238R, V245ECRF01_AE
Yang (2012)GZ110GZ110JN848867NoneNone  P4N, T7AP, K11T, V35T, T39K, K43E, V118I, D123N, T165I, K173AT, D177E, I178IMV, T200TI, Q207A, R211S, F214L, K238R, V245E, E291D, V292I, I293VCRF01_AE
 GZ113GZ113JN848870NoneNone  E6D, V35I, T39K, K43E, V118I, K122E, D123S, S162C, K173I, Q174K, D177E, Q207S, R211S, V245E, V276I, T286A, E291D, V292I, I293VCRF01_AE
 GZ158GZ158JN848878NoneNone  E6D, K11T, V35KT, T39EK, K43KE, V106I, V118I, K122E, D123S, I135T, S162C, K173I, Q174K, T200I, E203ED, Q207A, R211S, K238KR, V245E, T286A, E291D, V292I, I293V, T296TS, E297DCRF01_AE
 GZ204GZ204JN848886NoneNone  E6D, K11A, V35T, T39K, K43E, V60I, V118I, K122E, D123N, I135T, K166R, K173I, Q174K, D177E, I178M, T200I, I202IV, Q207A, R211S, F214L, K238R, V245E, A272AS, V276VI, T286A, E291D, V292I, I293VCRF01_AE
 GZ243GZ243JN848911NoneNone  E6D, K11A, V35T, T39K, K43E, V60I, V106VI, V118I, D123N, I142V, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, F214L, K238R, V245E, K281R, T286A, E291D, V292I, I293VCRF01_AE
Zeng (2012)CN0982CN0982JQ028219NoneNone  E6D, V8I, K11S, V35T, T39K, K43E, S68G, E79D, V118I, K122E, D123N, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, A272P, I274V, T290A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, V365A, K366R, A371V, K390R, A400T, T403M, E404D, T419I, E432D, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 CN1003CN1003JQ028223NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, D123N, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K220M, K238R, V245E, V276I, T286A, E291D, V292I, I293V, K311R, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376S, K390R, K395R, A400T, T403M, E432D, N447S, S468P, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 CN1217CN1217JQ028228NoneNone  E6D, V8I, V35T, T39K, K43E, V118I, K122E, D123S, I135T, S162C, K173I, Q174K, I178M, T200A, I202V, Q207N, R211S, K238R, V245E, T286A, V292I, I293V, P294Q, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554S, K558RCRF01_AE
 CN1291CN1291JQ028249NoneNone  E6D, K11T, V35T, T39E, V118I, K122E, D123S, S162C, K173I, Q174K, D177E, I202V, Q207G, R211S, K238R, V245E, A272P, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, E514D, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 CN1303CN1303JQ028256NoneNone V179DE6D, K11T, V35T, T39K, K43E, V118I, D123N, E138G, I142V, K173I, Q174K, D177E, Q207A, R211S, F214L, V245E, A272G, T286A, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 CN1326CN1326JQ028282NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123N, I135T, K173I, Q174K, D177E, I178V, T200I, Q207A, R211S, F214L, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
 CN0271CN0271JQ028328NoneNone  E6D, K11T, V35T, T39K, V60I, V111I, V118I, K122E, D123S, T165I, K173T, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, T286A, E291D, I293V, K311Q, E312T, I326V, I329V, G335D, M357R, G359S, K366R, A371V, V381I, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554S, I556VCRF01_AE
Frentz (2013)EHR-635887EHR-635887JX300606NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123N, I135T, K166R, K173I, Q174K, D177E, I178V, T200TA, Q207A, F214L, K238KR, V245ECRF01_AE
Kiertiburanakul (2013)X12TS041X12TS041KC994437NoneNone  E6D, V35T, T39K, K43Q, V60I, V106VI, V118I, K122E, D123S, I135T, K173I, Q174K, D177G, T200I, Q207A, R211S, F214FL, K238R, V245E, A272P, T286A, E291D, V292I, I293V, T296TA, A304E, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K395R, A400TCRF01_AE
 X12047X12047KC994379NoneNone  E6D, V35T, T39K, K43Q, V60I, K103R, V118I, K122E, D123S, I135T, S163C, T165TI, K173I, Q174K, D177E, T200I, Q207A, R211RS, F214L, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, I375V, K390R, K395R, A400TCRF01_AE
 X12TS033X12TS033KC994429NoneNone  V35VI, V60I, V118I, D121DH, K122E, D123S, I135IATV, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312TCRF01_AE
 X12TS029X12TS029KC994425NoneNone  E6D, V35T, T39K, K43Q, V60I, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245EK, A272P, T286A, E291D, V292I, I293V, A304E, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, T369A, A371V, K395RCRF01_AE
 R73248R73248KC810772NoneNone  E6D, K11T, V35T, T39K, K43E, I50IV, V106I, V118I, K122E, D123NS, S162C, K173I, Q174K, D177E, V179I, T200A, Q207A, R211S, V245ECRF01_AE
 R12081R12081KC994227NoneNone  E6D, K20KR, V35T, T39K, K43Q, V60I, K103R, V118I, K122E, D123S, I135IT, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, K263KE, L264LI, A272PCRF01_AE
 R71116R71116KC921945NoneNone  V35T, T39K, K43E, V106I, V118I, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, T200A, Q207A, R211S, K238RCRF01_AE
 R12112R12112KC994252NoneNone  E6D, K32KQ, V35T, T39K, K43Q, V60I, W88WC, K103KR, V118I, K122E, D123S, I135KRT, K173L, Q174K, D177E, T200I, Q207A, R211S, F214FL, K238R, V245E, A272P, K275KR, T286A, E291D, V292I, I293V, E312TCRF01_AE
 X12TS034X12TS034KC994430NoneNone  E6D, K20R, V35I, T39K, K43Q, V60I, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, T286A, E291D, V292I, I293V, T296TA, E312T, I326V, I329V, G335D, F346Y, M357K, G359S, K366R, A371V, K390R, K395R, A400TCRF01_AE
 R12152R12152KC994286NoneNone  E6D, K20R, E28EG, V35I, T39K, K43Q, V60I, K103KR, V106I, V118I, K122E, D123S, I135T, K173IT, Q174K, D177E, T200I, Q207A, L210LM, R211S, F214L, K238R, V245E, A272P, T286TA, E291D, V292I, I293V, P294T, L310LI, E312AT, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, T369A, A371L, K395R, A400TCRF01_AE
 X12061X12061KC994392NoneNone  E6D, V35T, T39K, K43Q, V60I, K103KR, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, T369A, A371VCRF01_AE
 R12028R12028KC994182NoneNone  E6D, V35T, T39K, K43Q, V60I, V106I, V118I, K122E, D123S, I135R, E138EG, R172RK, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, V254I, A272P, T286ACRF01_AE
 R73232R73232KC810757NoneNone  E6D, K11KT, V35T, T39EQ, I50IS, V118I, K122E, D123S, I142V, T165TA, K166R, K173I, Q174K, D177E, T200I, I202IV, Q207A, R211K, K238R, V245QCRF01_AE
 X12045X12045KC994377NoneNone  E6D, V35T, T39K, K43Q, V60I, V106I, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, E194EK, T200I, R206K, Q207A, L210LM, F214L, K238R, V245E, A272P, V276VI, T286A, E291D, V292I, I293V, E297K, A304E, K311A, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400TCRF01_AE
 R41035R41035KC970924NoneNone  E6D, V35T, T39K, K43E, V118I, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 R71173R71173KC921971NoneNone  V35T, T39K, K43E, V118I, K122E, D123S, K173I, D177E, V179I, D192I, T200I, I202V, Q207A, R211K, K238RCRF01_AE
 R72041R72041KC867586NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39K, K43E, V60I, S68G, V106I, V118I, K122E, D123S, I135T, K173T, Q174K, D177E, T200A, Q207A, R211S, K238R, V245ECRF01_AE
 X12062X12062KC994393NoneNone  P4PH, E6D, V35T, T39K, K43Q, V60I, V106I, V118I, K122E, D123S, I135T, S163ST, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, R356RK, M357K, G359S, K366R, T369A, A371V, K390R, K395RCRF01_AE
 X12TS026X12TS026KC994422NoneNone  E6D, V35I, T39K, K43Q, V60I, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329VCRF01_AE
 R71068R71068KC921402NoneNone  V35T, T39K, K43E, V118I, K122E, D123S, I135T, S162C, Q174E, D177E, I178M, G196A, T200A, E204K, Q207A, R211S, L228VCRF01_AE
 X12TS020X12TS020KC994416NoneNone  E6D, V35T, V60I, V118I, K122KE, D123S, I135T, S162A, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, V276I, T286A, E291D, V292I, I293V, E312T, D324DE, I326V, I329V, G335GD, P345Q, M357K, G359FS, K366R, A371V, I382T, K390R, A400T, W402XCRF01_AE
 R12033R12033KC994186NoneNoneV75L E6D, K22R, V35T, T39K, K43Q, V60I, V106I, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312N, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390RCRF01_AE
 X12TS018X12TS018KC994414NoneNone  E6D, V35T, T39K, K43Q, V60I, K103R, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329VCRF01_AE
 X12TS007X12TS007KC994403NoneNone  E6D, V35T, T39K, K43Q, V60I, K103R, V118I, K122E, D123S, I135K, K173L, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329VCRF01_AE
 R72037R72037KC867582NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39K, K43E, V60I, S68G, V118I, K122E, D123S, K173R, Q174K, D177E, Q207A, L210S, R211S, V245ECRF01_AE
 R12001R12001KC994162NoneNone  P4PR, E6D, K22K*, V35T, T39K, K43Q, V60I, V118I, K122E, D123S, I135IT, K173T, Q174K, D177E, T200V, Q207A, R211NS, F214L, K223KR, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, A371V, A376V, V381I, T386A, K390R, A400TCRF01_AE
 R12130R12130KC994268NoneNone  E6D, V35IT, T39K, K43Q, V60I, V118I, K122E, D123S, I135T, K166KR, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312TCRF01_AE
 R72017R72017KC867568NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39K, K43E, S68G, V118I, D121H, K122E, D123S, I135T, K173I, Q174K, D177E, V179I, Q207A, R211S, K238R, V245EQCRF01_AE
 R12060R12060KC994208NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, D123N, I142V, E169EK, K173I, Q174K, D177E, Q207A, R211N, K238R, V245Q, T286TA, E291D, V292I, I293IV, E297A, A299P, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, I375IV, A376AT, K390R, K395R, A400TCRF01_AE
 R41021R41021KC970917NoneNone  E6D, V35T, T39K, K43E, V118I, K122E, D123N, K173I, Q174K, D177E, T200I, Q207A, R211S, F214L, K238R, V245ECRF01_AE
 R12059R12059KC994207NoneNone  E6D, K11T, V35I, T39K, K43E, V118I, D123N, I142V, K173IL, Q174K, D177E, I178MV, T200I, Q207A, R211S, F214L, K238R, V245E, V276VI, T286A, E291ED, V292I, I293V, E312T, I326V, I329VCRF01_AE
 R72040R72040KC867585NoneNone  K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39K, K43E, V118I, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 R41014R41014KC970991NoneNone  V21I, V35I, T39A, W88C, V118I, K122E, D123S, S162C, K173R, Q174K, D177E, I178M, V179I, G196E, Q207A, R211N, K238R, V245E, E248D, K249RCRF01_AE
 R71TS230R71TS230KC921701NoneNone  V35T, T39K, K43E, V118I, K122E, D123N, I135T, S162C, K173I, Q174K, D177E, Q207A, R211S, K238R, V245ECRF01_AE
 R72050R72050KC867592NoneNone  V35L, E36N, I37F, T39EK, V118I, K122E, D123NS, I135T, K173I, Q174K, N175Y, Q207A, R211S, K238R, V245ECRF01_AE
 R12016R12016KC994174NoneNone V179DE6D, E28K, K32E, V35I, T39K, K43Q, V60I, W88C, K103R, V118I, K122E, D123S, I135T, K173IT, Q174K, D177E, T200I, E203ED, Q207AD, R211K, F214L, K238KR, V245E, A272P, T286A, E291D, V292I, I293VCRF01_AE
 R72194R72194KC857177NoneNone  T39K, K43E, V60I, W88C, V111I, V118I, D121H, K122E, D123S, K173IL, Q174N, Q207A, L210M, R211S, F214L, K238R, V245VECRF01_AE
 R72185R72185KC857169NoneNone  T39K, K43E, V106I, V118I, K122E, D123S, K173A, Q174K, D177E, Q207A, R211K, K238R, V245KCRF01_AE
Li (2013)28582858JQ901067NoneNone  E6D, V35T, T39K, K43E, V118I, K122E, D123S, I135T, T165I, K173R, Q174K, D177E, T200I, Q207A, R211S, F214L, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, E370EA, A371V, I375IV, K390R, K395R, A400T, E432D, N447S, R448K, D460N, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524E, I526V, A534S, A554S, I556VCRF01_AE
 28682868JQ901074NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200R, Q207A, R211S, F214L, K238R, V245D, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, K395R, A400T, E432D, R448K, D460N, D471E, Q480H, H483Y, L491P, K512R, L517I, S519N, Q524E, I526V, A534S, A554SCRF01_AE
 28692869JQ901075NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200R, Q207A, L210M, R211S, F214L, K238R, V245D, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, F346Y, M357K, G359S, K366R, A371V, K390R, K395R, A400T, E432D, N447S, R448K, D460N, D471E, Q480H, H483Y, L491P, K512R, L517I, S519N, Q524E, I526V, A534S, A554SCRF01_AE
 28732873JQ901079NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, T200R, Q207A, R211S, F214L, K238R, V245D, V276I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, A371V, K390R, K395R, A400T, E432D, N447S, R448K, D460N, D471E, Q480H, H483Y, L491P, K512R, L517I, S519N, Q524E, I526V, A534S, A554SCRF01_AE
Li (2013)23092309JQ302755NoneNone  E6D, K11T, K20R, V35T, T39K, K43E, V118I, K122E, D123N, I135T, T165I, K173I, Q174K, D177E, I178V, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, A371V, I382T, K390R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, E529D, A534S, A554TCRF01_AE
 20362036JQ302567NoneNone  E6D, K11KT, V35T, T39K, K43E, V118I, K122E, D123N, I135T, K173I, Q174K, D177E, I178V, G196GE, T200A, Q207A, R211N, F214FL, V245E, E291D, V292I, I293V, E312I, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, A534S, A554SCRF01_AE
Masimba (2013)TZ110TZ110KC537076NoneNone  T39G, V118I, E138A, K166R, K173S, D177E, I178V, V179I, T200A, I202V, Q207A, R211S, F214LCRF01_AE
Wu (2013)WHP55WHP55KC203280NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173M, Q174K, D177E, T200R, Q207A, R211S, F214L, V245DCRF01_AE
 WHP70WHP70KC203288NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173M, Q174K, D177E, T200R, Q207A, R211S, F214L, V245DCRF01_AE
 WHP54WHP54KC203279NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173M, Q174K, D177E, T200R, Q207A, R211S, F214L, V245DCRF01_AE
 AQP119AQP119KC203316NoneNone  E6D, V35T, T39KR, E40EQ, K43E, V118I, D121DH, K122KE, D123S, I135T, T139TA, S162N, K173IT, Q174K, D177E, T200I, Q207A, R211S, F214L, K238KR, V245ECRF01_AE
Zeng (2013)cdh31cdh31KC352201NoneNone  E6D, K11T, V35T, T39K, K43E, V118I, K122E, D123S, S162C, K173S, Q174K, D177E, I178M, I202V, E203D, Q207A, R211T, K238RCRF01_AE
 cdbc97cdbc97KC352169NoneNone  E6N, K11T, V35T, T39K, K43E, K49Q, V118I, K122E, D123S, I135T, F171Y, K173A, Q174K, D177E, I178M, T200I, Q207A, R211K, F214L, K238RCRF01_AE
 cdbc63cdbc63KC352135NoneNone  E6D, V35T, T39G, V118I, K122E, D123S, K173T, Q174K, D177E, V179T, G196E, T200A, Q207A, L210M, R211S, F214LCRF01_AE
Bartolo (2014)09AOHDP26309AOHDP263KF853691NoneNone  K11T, V35T, T39K, E40A, K43E, V118I, K122E, D123S, I142V, A158S, S163T, K173A, Q174K, D177E, G196E, T200TA, Q207A, H208HY, R211K, F214L, V245Q, A272P, T286A, A288AG, V292I, I293V, P294TCRF01_AE
 09AOHDP10009AOHDP100KF853612NoneNone  K11T, V35T, T39A, T107I, V118I, D123N, I135T, K173A, Q174K, D177E, T200A, I202V, Q207A, R211S, F214L, V245Q, E248D, D250T, A272P, T286A, E291D, V292I, I293V, P294T, L295M, E297DCRF01_AE