<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype CRF01_AE
Gene RT
Mutation V118I
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 3
Patients 37
Isolates 37
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Ariyoshi (2003)JPN25JPN25AY901426AZT, DDI, 3TC, D4TNoneM41L, D67N, L210W, T215YA98GE6D, K11T, V35T, T39K, K43E, E44D, V118I, D123N, I135T, K173I, Q174K, D177E, T200K, K201I, E204EV, Q207A, H208Y, R211N, K238R, V245ECRF01_AE
Hsu (2005)BAA154764BAA154764AY870165AZT, 3TC, D4T, DDINoneM41L, D67N, L210W, T215Y E6D, V35IT, T39K, K43E, E44A, V111I, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, V179I, T200TI, Q207A, H208Y, R211RK, K238R, V245E, A272P, E291D, I293V, E312A, I329V, G335D, M357K, R358RG, G359S, K366R, A371V, A376V, K390R, K395RCRF01_AE
 BAA157684BAA157684AY870188AZT, 3TCNoneM184V P4X, E6ED, K11T, I31L, V35T, T39K, K43E, K66KR, W88S, V111I, V118I, K122E, D123N, K173I, Q174K, D177E, I178L, T200A, Q207A, R211GS, F214L, K238R, V245E, K275Q, K277R, T286A, E291D, I293V, E297A, E312AT, I326V, I329V, G335D, F346FY, R356RK, M357K, G359S, K366R, A371V, K390RCRF01_AE
Non-B Workgroup (2005)TH_128TH_128AY605550AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, E44D, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, G196E, R206K, Q207A, R211D, K238R, V245ECRF01_AE
 TH_143TH_143AY605556AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, V60I, T69A, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I202V, Q207A, R211S, I244V, V245E, K249ECRF01_AE
 TH_153TH_153AY605565AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, V60I, V118I, K122E, D123S, K173L, Q174K, D177E, I178M, Q207A, R211D, K238R, V245ECRF01_AE
 TH_157TH_157AY605570AZT, DDINoneM41L, D67N, K70R, L210W, T215F, K219Q D17G, G18R, K20R, V35T, T39K, K43E, E53D, V60I, L92M, V118I, K122E, D123S, S162Y, K173I, Q174K, D177E, I178M, Q207A, R211S, D218E, L228H, K238R, V245E, V254ACRF01_AE
 TH_165TH_165AY605579AZT, DDINoneM41L, D67N, T69D, L210W, T215Y G18R, P19T, V35T, T39K, K43E, E44D, V60I, V118I, K122E, D123S, I135V, S162C, K173I, Q174K, D177E, T200I, Q207A, R211N, K238R, I244V, V245E, I257R, Q258PCRF01_AE
 TH_185TH_185AY605593AZT, DDINoneM41L, D67N, M184I, L210W, T215Y K20R, V35T, T39K, K43E, E44A, V60I, V118I, K122E, D123S, K173I, Q174K, D177E, G196E, Q207A, R211N, V245ECRF01_AE
 TH_197TH_197AY605602AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, E44D, V60I, V118I, K122E, D123S, S162N, K173I, Q174K, D177K, I178M, Q207A, R211N, K238RCRF01_AE
 TH_207TH_207AY605611AZT, DDINoneM41L, D67N, K70R, L210W, T215F, K219Q D17G, G18W, P19T, V35T, T39K, K43E, V60I, V118I, K122E, D123S, R172K, K173I, Q174K, D177E, I178M, G196E, Q207K, R211S, D218E, V245KCRF01_AE
 TH_212TH_212AY605615AZT, DDINoneM41L, D67N, L210W, T215Y Q23T, W24V, P25A, V35T, T39K, K43E, V60I, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, Q207A, R211G, K238R, V245ECRF01_AE
 TH_230TH_230AY605636AZT, DDINoneM41L, D67N, L210W, T215Y M16W, D17L, V35T, T39K, K43E, E44A, V60I, V118I, K122E, D123S, K173T, Q174K, D177E, T200A, Q207A, H208F, R211K, K238R, V245ECRF01_AE
 TH_242TH_242AY605648AZT, DDINoneM41L, L210W, T215Y V35T, T39K, K43E, S68G, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, E203D, Q207A, R211N, K220Q, V245E, E248DCRF01_AE
 TH_429TH_429AY901838AZT, DDINoneM41L, D67E, L210W, T215Y V35T, T39K, K43E, E44I, S68G, V118I, K122E, D123S, I135T, S162A, T165I, K173I, Q174K, D177E, Q207A, R211N, L234HCRF01_AE
 TH_439TH_439AY901842D4T, DDINoneM41L, L74I, V75T, L210W, T215Y V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245ECRF01_AE
 TH_448TH_448AY901846D4T, DDINoneM41L, D67G, L74V, T215Y, K219NY181CV35T, T39K, K43E, E44A, S68G, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, Q207A, K238R, V245ECRF01_AE
 TH_473TH_473AY901852D4T, DDINoneM41L, D67E, L210W, T215Y V35T, T39R, K43E, S68G, V118I, K122E, D123N, K173A, Q174K, D177E, I178M, V179I, T200K, Q207A, R211N, V245DCRF01_AE
 TH_474TH_474AY901853D4T, DDINoneM41L, D67N, T69D, K70R, V75L, L210W, T215Y V35T, T39K, K43E, E44D, V60I, V118I, K122E, D123S, K173I, Q174K, D177E, Q207A, H208Y, R211N, V245KCRF01_AE
 TH_477TH_477AY901855DDC, AZTNoneM41L, T69D, L210W, T215YK238TV35T, T39K, K43E, E44D, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, S191C, G196E, T200A, Q207A, R211S, V245ECRF01_AE
 TH_487TH_487AY901858AZT, DDINoneT215F, K219Q K22R, V35T, T39K, K43E, V60I, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, E194D, Q207A, R211S, F214L, K238R, V245ECRF01_AE
 TH_529TH_529AY901871AZT, DDINoneM41L, D67N, L210W, T215FF227LV35T, T39K, K43E, N57Y, V60I, V118I, K122E, D123S, I135T, K173I, Q174K, I178M, T200I, Q207A, R211S, L228P, V245ECRF01_AE
 TH_561TH_561AY901879AZT, DDINoneM41L, D67N, L210W, T215YE138KK32I, V35T, T39K, K43E, V118I, K122E, D123S, S162Y, R172K, Q174E, D177E, I178V, Q207A, R211N, K238R, V245ECRF01_AE
 TH_591TH_591AY901884DDC, AZTNoneM41L, D67E, V75M, L210W, T215YA98GK20R, V35T, T39K, K43E, V60I, S68G, V118I, K122E, D123N, K173A, Q174K, D177E, Q207A, R211N, K238R, V245ECRF01_AE
 TH_593TH_593AY901886AZT, DDINoneM41L, D67N, T69D, L210W, T215Y V35T, T39K, K43E, V60I, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, E203D, Q207A, R211S, K238R, V245ECRF01_AE
 TH_601TH_601AY901891AZT, 3TCNoneM41L, D67N, L210W, T215YV179DV35T, T39K, K43E, E44D, V111I, V118I, K122E, D123S, K166R, K173I, Q174K, I178L, T200A, E204D, Q207A, R211S, V245ECRF01_AE
 TH_618TH_618AY901895D4T, 3TCNoneM41L, D67N, K70R, M184I, L210W, T215Y, K219QA98GV35T, T39K, K43E, V60I, K102Q, V118I, D123N, K173I, Q174K, D177E, T200A, Q207A, H208Y, R211S, K238R, V245ECRF01_AE
 TH_628TH_628AY901900D4T, DDINoneD67N, K70R, K219Q V35T, T39K, K43E, V60I, K64N, V111I, V118I, K122E, D123N, N136T, K173T, Q174K, D177E, Q207A, R211S, F214L, D218E, V245ECRF01_AE
 TH_643TH_643AY901908AZT, DDINoneM41L, D67N, L210W, T215YA98GV35T, T39K, K43E, V60I, V118I, K122E, D123S, T139A, K173I, Q174K, D177E, I178M, Q207A, R211N, K238R, V245ECRF01_AE
 TH_655TH_655AY901918AZT, DDINoneM41L, D67N, T69D, L210W, T215Y V35T, E44D, V118I, K122E, D123N, I135T, I142V, K173T, Q174K, D177E, I178M, T200I, Q207A, R211S, V245ECRF01_AE
 TH_665TH_665AY901920AZT, 3TCNoneM41L, D67N, M184V, L210W, T215YA98GV35T, T39K, K43E, V118I, K122E, D123S, I135L, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, D237G, V245E, S251MCRF01_AE
 TH_696TH_696 AZT, DDINoneM41L, L210W, T215Y V35T, T39K, K43E, E44A, V60I, S68G, V118I, K122E, D123S, I142V, K166R, K173I, Q174K, D177E, I178M, T200A, Q207A, R211NCRF01_AE
 TH_711TH_711 D4T, DDINoneM41L, D67N, L74I, V75T, L210W, T215Y K32I, V35T, T39K, K43E, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, G196E, T200I, Q207A, R211N, K238R, V245ECRF01_AE
 TH_713TH_713 AZT, DDINoneM41L, D67N, L210W, T215Y V35T, T39K, K43E, V60I, V118I, K122E, D123S, I135V, K173I, Q174K, D177E, Q207A, R211S, V245ECRF01_AE
 TH_718TH_718AY901936AZT, DDINoneM41L, D67N, T69D, L210W, T215Y V35T, T39K, K43E, E44D, V60I, K102Q, V118I, K122E, D123S, S162Y, E169D, Q174E, D177E, I178L, G196E, T200E, K201R, E204K, Q207A, R211D, K238R, V245ECRF01_AE
 TH_754TH_754AY901947AZT, DDINoneM41L, L210W, T215Y V35T, T39K, K43E, V118I, K122E, D123S, K173V, Q174K, D177E, I178M, V179I, T200I, Q207A, R211N, L228H, K238R, V245KCRF01_AE
 TH_408TH_408 AZT, D4T, DDINoneM41L, D67E, V75M, L210W, T215Y V35T, T39K, K43E, E44D, V60I, S68G, V118I, K122E, D123N, K166R, K173L, Q174K, D177E, I178M, Q207A, R211N, V245ECRF01_AE