<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation V75I
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 7
Patients 16
Isolates 16
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)SA71_2504SA71_2504AY589838AZT, D4T, DDINoneV75I, F77L, F116Y, Q151M G15A, V35T, E36A, T39E, S48T, S68G, V111I, K122E, D123G, I135V, K173A, T200E, Q207A, R211K, V245Q, A272P, K275Q, Q278K, T286A, E291D, V292I, I293VC
Pillay (2008)DR59DR59AY589911D4T, DDINoneA62V, K65R, V75I, F77L, F116Y, Q151M T39E, S68G, A98S, K122A, S162SCNY, S163ST, K173A, Q174K, D177E, I178L, T200A, Q207D, R211K, V245Q, A272P, Q278H, I293V, S322A, Q334XC
 DR68DR68AY589917AZT, 3TCNoneA62V, K65KR, V75I, F77L, F116Y, Q151M, M184V V35T, T39EK, E40EK, S48T, S68G, T69TI, K122E, D123S, S162C, K166KR, K173T, Q174K, I178IL, E194AT, G196E, T200A, I202IV, Q207E, F214L, V245Q, E248D, A272P, E291D, V292VI, I293V, E297KC
 DR10203ZA.DR102AY589937D4T, DDINoneA62AV, V75I, F77FL, F116Y, Q151M A33AV, V35T, T39E, S68SG, T69S, K122E, D123S, K173A, D177E, T200A, Q207E, R211K, V245Q, S251N, A272P, K275Q, K277R, T286A, E291D, V292I, I293VC
Van Zyl (2013)42712.ZA.MP001KC423906AZT, DDINoneV75I, M184VK103N, V108II31L, V35T, V60I, K122E, D123N, K173A, Q174R, D177E, T200A, I202V, Q207E, R211K, V245EC
 327211.ZA.GT1915KC423704AZT, 3TC, DDINoneD67N, T69D, K70R, V75I, T215F, K219Q V35T, T39E, V60I, W88C, K122E, I132L, K173A, D177E, I178L, G196E, T200A, K201R, E203ED, E204K, Q207E, F214L, L228R, V245Q, E248DC
Acharya (2014)DGP072DGP072KJ185242TDF, 3TCNoneA62V, V75I, F77L, Q151M V35T, E36A, T39D, S48T, V60I, L109I, D121H, K122E, K173I, D177E, I178M, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293VC
 DGP025DGP025KJ185195TDF, 3TCNoneA62V, K70N, V75I, F77L, Y115F, F116Y, Q151M, M184VG190A, F227LV35T, E36A, T39D, S48T, K49R, V60I, D121Y, K122E, K173T, D177E, T200A, Q207E, R211K, V245Q, A272P, K275Q, K277R, T286A, E291D, V292I, I293VC
Steegen (2014)09ZAKS02209ZAKS022KJ176304D4T, 3TCNoneV75I, M184VV106M, V179DE6K, K20R, I31L, V35T, E36A, T39E, S48T, E53D, K122E, I132L, S162F, Q174L, T200A, Q207E, R211K, F214L, V245M, A272P, K277R, E291D, V292I, I293VC
Neogi (2016)67013.ZA.EC722KT592865D4T, 3TCNoneM41L, A62V, V75I, M184V, T215FV106M, G190A, F227LP4S, I31L, V35I, E36A, T39E, L109I, S162A, F171Y, K173A, Q174K, T200A, I202V, Q207A, R211K, V245QC
 86913.ZA.WC351KT593537TDF, AZT, 3TCNoneM41L, A62V, V75I, M184V, T215YA98G, V106M, Y188F, F227LI31L, V35I, T39E, K43R, E44D, S48T, L109I, V118I, D121HY, K122E, I135L, I142IV, S162A, K173T, D177E, V189I, T200A, I202V, Q207E, L210T, R211K, D218E, H221Y, V245QC
 43313.ZA.WC301KT593501TDF, 3TCNoneV75I, M184VV106M, V179DP4H, I31L, V35T, T39E, I47L, S48T, V118I, K122E, D123N, K126Q, I132L, S162C, I180L, T200A, Q207E, R211G, F214L, V245TC
Posada Cespedes (2017)252114.ZA.GT3306 AZT, D4T, DDINoneA62V, K65KR, V75I, F77FL, F116FY, Q151QKLM V8VI, K20KR, V35T, T39E, S48T, V60I, S68G, V118VI, D121C, K122E, I135V, E138A, S162C, K173T, Q174K, D177DG, T200A, Q207D, R211K, W212W*, V245Q, E248DC
 313606.ZA.GT015KX539561AZT, 3TCNoneK65R, K70R, V75I, F77L, F116Y, Q151MK103N, V106MV21I, K32I, V35T, T39K, S48T, K64KQ, S68G, V118I, K122E, D123S, T139A, I142T, T165I, Q182H, G196E, T200A, Q207E, F214L, L228Q, A272P, Q278H, T286A, E291D, V292I, I293VC
 204713.ZA.GT2656KX542999TDF, 3TCNoneV75I, M184VK103N, V108I, L234IV8I, K11Q, V35T, T39E, K122E, D123K, I132L, S162C, K173A, Q174A, D177E, I195L, G196E, T200A, Q207E, R211K, H221Y, L228H, V245QC
 258015.ZA.GT4543 TDF, 3TCNoneD67N, K70R, V75I, M184VK101KEK20R, V35T, T39D, S48T, V60I, D121H, K122E, I132L, I135V, K173A, Q174K, D177E, T200E, Q207E, V245Q, D250EC