<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation L74V
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 5
Patients 5
Isolates 5
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Gibb (2002)DMG9595_w75 ABC, 3TCNoneL74V, Y115F, M184VV179VDV35T, T39E, S48T, V118I, K122E, D123N, E138A, I142V, K173I, Q174K, P176PS, T200E, Q207K, R211K, F214L, V245Q, E248D, K249Q, A272P, K275R, K277R, Q278H, E291D, V292I, I293V, P294E, D324E, I329L, Q334H, G335D, R356K, M357T, G359T, T369A, A376T, T377R, K390R, E396D, T397IC
Non-B Workgroup (2005)TK3009TK3009 AZT, 3TC, D4T, DDINoneL74V, M184V V35T, E36A, T39E, S48T, K122E, D123N, A158S, K173A, D177E, T200A, Q207E, Q222XC
Sen (2007)T076NPT76-PLEF186980AZT, D4T, 3TC, DDINoneD67G, K70R, L74V, K219Q V35T, E36A, T39D, S48T, K64N, D121Y, K122E, I135T, T165I, R172K, K173A, Q174R, D177E, I178L, T200A, E203K, Q207E, R211K, F214L, D218E, Q242QK, V245Q, A272P, K277R, L283I, I293V, G335D, R356K, G359AT, A360AT, V365VI, K390KR, A400T, E404DC
Pillay (2008)DR33DR33AY589890D4T, DDINoneL74V V35T, T39E, S48T, V60I, K122E, K173A, Q174K, D177E, I178L, T200A, K201KR, I202V, Q207E, R211K, V241I, V245Q, A272S, E291D, V292I, I293VC
Sylla (2008)B7173B7173_C2EF5256623TC, DDINoneD67N, L74V, M184I V35T, T39E, S48T, V60I, A98S, D121H, K122E, I135V, K173A, Q174K, P176T, I178L, T200A, Q207E, R211K, V245M, D250E, A272P, K277R, T286A, E291D, V292I, I293V, D324E, Q334H, G335D, R356K, G359T, T377M, K390R, A400T, E404D, V435VIC

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