<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation T69N
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 5
Patients 14
Isolates 14
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Cuevas (2002)CU81CU81AF425462AZT, DDINoneD67N, K70R V35T, T39E, K64R, T69N, A98S, D121H, K122E, D123S, K173A, D177E, I178L, I195M, Q197P, T200A, Q207EC
Non-B Workgroup (2005)SA63_10701070A_12MAY589806AZT, D4T, DDINone  V35T, T39E, T69N, K122E, D123G, K173T, Q174K, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293VC
 SA65_1158SA65_1158AY589817D4T, DDINone  K20R, V35T, E36A, T39E, S48T, T69N, K122E, D123N, K166R, K173T, D177E, I178M, T200A, E204K, Q207E, V245L, A272P, K277R, E291D, V292I, I293V, P294TC
 SA67_1216SA67_1216AY589823D4T, DDINone  V35T, E36A, T39E, S48T, T69N, K122E, D123G, K173T, T200A, Q207E, V245H, K277R, T286A, E291D, V292I, I293VC
 SA70_1529SA70_1529AY589835DDI, D4TNone  V35T, T39E, S48T, T69N, K122E, K173A, T200A, Q207A, R211K, V245Q, T286A, E291D, V292I, I293VC
 IL293IL293AY901766AZT, 3TC, DDINoneK70R, M184V T39E, K64R, T69N, A98S, K122E, D123S, A158S, K173A, D177E, T200A, Q207EG, H208HY, R211K, H235HY, V245QC
Rodrigues (2005)BLF_Pat10BR03SP09AY643230AZTNone  V35T, T39D, T69N, K122E, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, K277R, E291D, V292I, I293V, P294TC
Deshpande (2009)Pat24814artFJ530693AZT, 3TCNoneD67N, K70R, M184V, T215F, K219EA98AGV35T, T39E, S48T, V60I, T69N, V118I, D121H, K122E, I135T, K173AT, D177E, I178M, T200A, E204K, Q207E, F214L, E224D, V245QC
 Pat21316RTFJ530728AZT, 3TCNoneM41L, D67N, K70R, M184V, T215F, K219QA98G, K101EQ, G190AK20R, E28EK, V35T, T39D, E44D, S48T, V60I, T69N, D121H, K122E, F124FV, I135T, K173A, Q174R, I178M, T200A, Q207E, R211RK, V245Q, L246WC
Van Zyl (2013)89684KC424309D4T, 3TCNoneM184V K22KN, V35T, E36A, T39E, S48T, T69N, K122E, T128S, I135V, S162C, K173A, Q174K, D177E, I178M, T200A, E204D, Q207D, R211K, V245Q, D250E, A272P, T286V, E291D, V292I, I293VC
 14862923KC423895ABC, 3TCNone  E28R, K32E, V35T, E36A, T39E, S48T, V60I, T69N, K122A, G155V, K173T, D177E, T200A, Q207E, V245QC
 1098515KC424108D4T, 3TCNoneM184VY181CP4PS, K22KR, V35T, T39EK, S48T, T69N, K122KE, A158S, K173A, D177E, T200A, Q207E, V245QC
 1255898KC424344D4T, 3TCNoneA62AV, M184V V35T, E36A, T39E, E40D, S48T, T69N, K122E, D123N, I135V, I159IV, K173T, Q174K, D177E, G196E, Q207D, R211K, K219KT, P243T, V245QC
 13131335KC423069D4T, 3TCNone Y181CV35T, T39E, S48T, T69N, K122E, D123N, K173T, Q174K, T200A, Q207A, R211K, V245QC