<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation S68G
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 5
Patients 32
Isolates 35
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)SA71_2504SA71_2504AY589838AZT, D4T, DDINoneV75I, F77L, F116Y, Q151M G15A, V35T, E36A, T39E, S48T, S68G, V111I, K122E, D123G, I135V, K173A, T200E, Q207A, R211K, V245Q, A272P, K275Q, Q278K, T286A, E291D, V292I, I293VC
 SA81_DR26SA81_DR26AY901714D4T, DDINoneA62V, K65R, V75T I2V, V35T, T39E, S48T, E53D, S68G, V118I, K122E, D123S, I135T, E138A, E169ED, K173AT, Q174K, I178M, T200A, Q207E, R211RK, F214L, K219G, V245VE, D250E, K263KN, A272P, K277R, L283I, T286A, E291D, V292I, I293V, V317AC
 TK1021TK1021 AZT, 3TC, D4T, ABC, DDINoneK65R, M184V V35T, E36A, T39E, S48T, V60I, S68G, V90I, K122E, D123S, I135V, E138A, K166R, K173T, E194X, T200A, Q207D, R211K, V245Q, E248D, A272P, K275KR, K277R, T286A, E291D, V292I, I293VC
Pillay (2008)DR59DR59AY589911D4T, DDINoneA62V, K65R, V75I, F77L, F116Y, Q151M T39E, S68G, A98S, K122A, S162X, S163ST, K173A, Q174K, D177E, I178L, T200A, Q207D, R211K, V245Q, A272P, Q278H, I293V, S322A, Q334XC
 DR68DR68AY589917AZT, 3TCNoneA62V, K65KR, V75I, F77L, F116Y, Q151M, M184V V35T, T39EK, E40EK, S48T, S68G, T69TI, K122E, D123S, S162C, K166KR, K173T, Q174K, I178IL, E194AT, G196E, T200A, I202IV, Q207E, F214L, V245Q, E248D, A272P, E291D, V292VI, I293V, E297KC
 DR2602ZA.DR26AY589883D4T, DDINoneA62V, K65R, V75T I2V, V35T, T39E, S48T, E53D, S68G, V118I, K122E, D123S, I135T, E138A, E169ED, K173AT, Q174K, I178M, T200A, Q207E, R211RK, F214L, K219G, V245VE, D250E, K263KN, A272P, K277R, L283I, T286A, E291D, V292I, I293V, V317AC
Van Zyl (2013)352210.ZA.GT1284KC423114D4T, 3TCNoneM184VE138KV35T, E36A, T39E, S48T, V60I, S68G, K122E, D123S, K173T, Q174K, D177E, T200A, E204D, V245QC
 86009.ZA.WC039KC424317AZT, DDINoneT69~K103N, Y181CL34I, V35T, E36A, T39E, S48T, S68G, K122E, S162C, K173A, Q174K, D177E, T200A, E203EK, Q207E, R211K, V245QC
 406911.ZA.GT2008KC423750AZT, 3TCNoneK65R, M184V, K219EL100I, K103NV35T, E36A, T39E, V60I, S68G, K122E, D123S, T139V, K173A, D177E, V179VI, T200A, E203K, Q207A, R211K, D218E, V245QC
 175012.ZA.GT2261KC423915TDF, 3TCNoneD67DG, K70R, T215TFIS, K219KEK103KN, V106MV35T, T39E, E53D, S68G, S105A, L109I, K122E, D123N, K173T, T200A, I202IV, Q207E, R211K, V245QC
Neogi (2016)712213.ZA.EC567KT592764AZT, 3TCNoneT215YK103N, P225HE28K, V35T, T39E, S48T, S68G, K101Q, K122E, D123N, I135T, S162C, R172K, K173A, D177E, I178L, T200A, E203D, Q207E, R211K, V245QC
 28013.ZA.NL075KT593448AZT, 3TCNoneF116FY, Q151M, M184VK103N, V108I, K238TK20R, E29EK, V35T, T39E, S48T, V60I, S68G, K122E, D123G, T139I, K173A, Q174K, D177E, I178IM, T200A, Q207A, R211K, F214L, L228HN, V245QC
 14513.ZA.NL081KT593453TDF, 3TCNoneM184VY181CP4S, V35T, T39E, S48T, V60I, S68G, T69N, D121Y, K122E, I135R, T139R, S162C, K173A, V179I, T200A, Q207D, R211K, F214L, H221Y, D237DN, V245QC
 226813.ZA.GT2690KT593058AZT, 3TCNoneK65R, K70TK101E, Y181C, G190AV35T, T39E, S48T, V60I, S68G, D121Y, K122E, K173T, Q174K, D177E, I178L, T200A, Q207D, R211K, L228R, V245QC
Posada Cespedes (2017)129615.ZA.EC1676 TDF, 3TCNoneM41L, D67N, T69DN, K70R, M184V, T215Y, K219EA98GV35T, T39N, V60VI, S68G, K122E, D123N, K173A, Q174R, D177E, E194K, G196E, T200A, E203D, Q207E, R211K, V245QC
 158815.ZA.GT4457 AZT, 3TCNoneK65R, D67N, K219EK101E, V106M, Y181C, G190AE6K, V8I, K20R, V35T, E36A, T39E, S48T, V60I, S68G, K122E, D123S, A158S, T165I, K173A, Q174K, D177E, T200A, I202IV, Q207E, R211K, V245QC
 317607.ZA.GT216 AZT, DDINone V179EV35T, T39A, S48T, V60I, S68G, K122E, I135R, S162A, S163T, K173A, Q174R, P176K, D177E, G196E, T200A, Q207E, R211K, V245N, E248ED, D250XC
 539812.ZA.NL037KX542424TDF, 3TCNoneM184VV179D, Y188LV35T, T39E, S48T, V60I, S68G, K103R, K122E, D123S, I135T, K166R, K173A, D177E, T200A, Q207E, R211K, F214FL, V245QC
 122914.ZA.EC1096KX543730AZT, 3TCNoneM184V, T215L, K219QV106M, V108I, E138K, F227L, M230LP4S, V35T, T39E, S48T, S68G, K104R, K122E, D123G, K173A, D177E, T200A, Q207E, L210LS, R211K, F214L, L228R, V245QC
 533912.ZA.EC160KX541633TDF, 3TCNone  P4S, V35T, T39E, V60I, S68G, K122E, D123N, I135R, T165I, K173S, Q174K, D177E, I178L, T200A, Q207T, R211K, V245QC
 508615.ZA.GT4197 TDF, 3TCNoneD67G, K70R, M184V, K219E K32Q, V35K, E36A, T39E, S48T, S68G, K122E, D123S, I135T, S162F, K173A, D177E, G196K, T200A, Q207K, R211K, F214L, V245QC
 575515.ZA.EC1670 AZT, 3TCNoneK65RK101E, G190SP4S, V35T, T39E, S48T, S68G, K122E, D123N, E138A, I142V, S162C, K173A, D177E, T200A, E204Q, Q207D, R211K, V245QC
 130815.ZA.EC1615 TDF, 3TCNoneM184VK103N, P225HK11R, K32R, V35R, T39D, E40D, S48T, E53D, V60I, S68G, D121Y, K122E, I135L, T139S, K173A, Q174K, T200A, Q207E, R211K, V245QC
 717014.ZA.EC992KX544105ABC, 3TCNone  P4S, K11Q, V35T, E36A, T39E, S48T, V60I, S68G, K122E, D123G, S162C, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, L228H, V241A, V245QC
 252114.ZA.GT3306 AZT, D4T, DDINoneA62V, K65KR, V75I, F77FL, F116FY, Q151QKLM V8VI, K20KR, V35T, T39E, S48T, V60I, S68G, V118VI, D121C, K122E, I135V, E138A, S162C, K173T, Q174K, D177DG, T200A, Q207D, R211K, W212W*, V245Q, E248DC
 313606.ZA.GT015KX539561AZT, 3TCNoneK65R, K70R, V75I, F77L, F116Y, Q151MK103N, V106MV21I, K32I, V35T, T39K, S48T, K64KQ, S68G, V118I, K122E, D123S, T139A, I142T, T165I, Q182H, G196E, T200A, Q207E, F214L, L228Q, A272P, Q278H, T286A, E291D, V292I, I293VC
 138514.ZA.EC1410 AZT, 3TCNoneM184VV106M, Y188F, F227LP4S, K20R, V35T, T39E, S48T, S68G, K104R, K122E, D123S, I135T, K173A, Q174R, D177E, V179I, T200A, I202V, Q207A, R211K, H221Y, V245KC
 574915.ZA.EC1647 AZT, DDINoneT69D K11Q, T27S, V35T, E36A, T39E, S48T, V60VI, S68G, D121Y, K122E, D123GS, I135T, E138A, S162C, K173E, T200A, Q207E, R211K, V245QC
 91611.ZA.WC127KX541552AZT, 3TC, DDINoneD67G, K70R, M184V, K219QV106M, V179DV35K, E36A, T39D, E40D, S48T, S68G, V90I, K103R, K122E, D123S, I135M, S162A, K173A, T200A, E203A, Q207E, R211K, F214L, V245QC
 226813.ZA.GT3052KX543326AZT, 3TCNoneM41L, K65R, K70N, K219KQK101E, Y181C, G190AV35T, E36EK, T39E, S48T, V60I, S68G, T69I, D121Y, K122E, K126KR, K173T, Q174K, D177E, I178L, T200A, Q207D, R211K, L228R, V245QC
 429514.ZA.GT3268KX544165TDF, 3TCNoneK65R, K70T, Y115F, M184VA98G, K103N, V106MK20R, K32E, V35T, T39K, V60I, S68G, T69I, W88CS, D121H, K122E, I135K, K173T, Q174KR, D177E, I178L, T200A, Q207E, R211K, F214FL, L228Q, V245Q, E248DC
 229514.ZA.GT3536KX544379AZT, 3TCNoneK65RV108I, Y181CE6EK, V35T, T39A, K46Q, S48T, S68G, K122E, D123DG, S162SC, K173A, D177E, T200A, Q207H, R211K, H221Y, V245QC
  14.ZA.GT3888 AZT, 3TCNoneK65RV108I, Y181CE6EK, V35T, T39A, K46Q, S48T, S68G, K122E, S162C, K173A, D177E, T200A, Q207H, R211K, H221Y, V245QC
 242215.ZA.GT4126 AZT, 3TCNoneM184VY188LV35T, T39E, S48T, S68G, K102R, V106I, K122E, D123E, I135T, K173A, Q174K, D177E, T200A, Q207D, R211K, D250EC
 175014.ZA.GT3689 TDF, 3TCNoneD67DG, K70R, T215TFIS, K219KEV106MV35T, T39E, E53D, S68G, K101KR, S105A, L109I, K122E, D123N, K173T, I195X, G196X, T200A, I202IV, Q207E, R211K, V245QC