<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation D67G
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 6
Patients 12
Isolates 15
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Kantor (2002)TCDD-23TCDD-23_1AY090850DDC, AZTNoneD67G, K70R, K219Q V35T, T39E, S48T, K64N, V90I, K122E, D123S, E138A, K173T, Q174K, T200A, E203K, Q207E, R211K, F214L, L228R, V245E, E248DC
Sen (2007)T076NPT76-PLEF186980AZT, D4T, 3TC, DDINoneD67G, K70R, L74V, K219Q V35T, E36A, T39D, S48T, K64N, D121Y, K122E, I135T, T165I, R172K, K173A, Q174R, D177E, I178L, T200A, E203K, Q207E, R211K, F214L, D218E, Q242QK, V245Q, A272P, K277R, L283I, I293V, G335D, R356K, G359AT, A360AT, V365VI, K390KR, A400T, E404DC
Kassaye (2009)TCDD-23TC23_2003FJ445712DDC, AZTNoneD67G, T69T_T, K70R, K219Q V35T, T39E, S48T, V60I, K64N, K103KR, V118I, K122E, D123S, E138A, T139A, K173T, Q174K, T200A, I202V, E203K, Q207E, R211K, F214L, D218E, L228HR, V245E, E248DC
Van Zyl (2013)328409.ZA.GT829KC424332AZT, DDINoneD67G E6D, V35T, T39E, W88C, K122E, D123N, E138G, A158S, K173T, Q174K, V179T, T200AE, I202IV, R211K, F214LC
  10.ZA.GT1166KC423006AZT, DDINoneD67G E6D, V35T, T39E, W88C, K122E, D123N, E138G, A158S, K173T, Q174K, V179T, T200E, I202V, R211K, F214L, Q242~C
Neogi (2016)711413.ZA.EC517KT592727TDF, 3TCNoneD67G, T69D, K70R, M184V, K219QL100I, K103NK20R, V35T, T39E, V60I, V106VL, K122E, D123G, I135V, T139Q, I142T, K173A, D177G, V179N, T200A, E203K, Q207E, L228H, V245QC
 558113.ZA.EC755KT592886AZT, 3TCNoneM41L, D67G, V75M, M184V, L210W, T215YK101N, V108I, Y181C, G190A, F227LE28A, K32E, V35T, T39R, K43E, E44D, S48T, W88C, K122E, D123S, S162C, K173A, D177E, T200A, E203K, Q207E, R211RK, H221Y, K223E, L228R, V245QC
Posada Cespedes (2017)75912.ZA.WC233KX542502AZT, 3TCNoneD67G, K70EY181YC, G190AV35T, E36A, T39E, S48T, S68R, K122E, D123NS, K173A, Q174K, D177E, G196V, T200A, Q207E, H221HY, V245LC
 45312.ZA.WC254KX542519AZT, 3TCNoneD67G, T69D, K70R, M184V, K219QK101P, K103N, P225HP4S, K20R, E28K, K32R, V35T, T39E, S48T, V60I, A98S, K122E, D123S, S162H, K166R, K173S, D177G, T200A, I202V, E203K, Q207E, R211K, V245QC
 508615.ZA.GT4197 TDF, 3TCNoneD67G, K70R, M184V, K219E K32Q, V35K, E36A, T39E, S48T, S68G, K122E, D123S, I135T, S162F, K173A, D177E, G196K, T200A, Q207K, R211K, F214L, V245QC
 495315.ZA.GT4064 D4T, 3TCNoneD67G, K70E, M184VK101E, V106M, G190A, F227FLK20R, V35T, E36A, T39E, S48T, V60I, K122E, I142T, K173T, Q174R, T200AE, Q207E, R211K, L228H, V245QC
 416015.ZA.GT4343 TDF, 3TCNoneD67G, T69D, K70R, V75M, M184V, T215I, K219QV106M, Y181C, F227LI31L, L34I, V35T, T39E, S48T, V60I, K82R, K122E, D123S, I135R, T165I, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245QC
 91611.ZA.WC127KX541552AZT, 3TC, DDINoneD67G, K70R, M184V, K219QV106M, V179DV35K, E36A, T39D, E40D, S48T, S68G, V90I, K103R, K122E, D123S, I135M, S162A, K173A, T200A, E203A, Q207E, R211K, F214L, V245QC
 151514.ZA.GT3236KX544142TDF, 3TCNoneD67G, T69D, K70R, V75M, M184V, T215I, K219KQV106M, Y181C, F227LI31L, L34I, V35T, T39E, S48T, V60I, K82R, K122E, D123S, I135R, T165I, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245QC
 328413.ZA.GT2987KX543282AZT, DDI, D4T, 3TC, TDFNoneD67G, K70R, M184V, K219E E6D, V35T, T39E, T69N, W88C, V118I, K122E, D123N, I135T, E138G, A158S, K173T, Q174K, V179IT, T200E, I202V, E203K, R211K, F214LC